AS3D Human


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Human Gene Lists U
ubiquitin-protein ligase activity, IEA281 genes
ubiquitin ligase complex, IEA254 genes
UCH, Ubiquitin carboxyl-terminal hydrolase71 genes
ubiquitin cycle, IEA67 genes
ubiquitin-dependent protein catabolism, IEA60 genes
ubiquitin, Ubiquitin family. This family contains a number of ubiquitin-like proteins: SUMO (smt3 homologue), Nedd8, Elongin B, Rub155 genes
UQ_con, Ubiquitin-conjugating enzyme. Proteins destined for proteasome-mediated degradation may be ubiquitinated. Ubiquitination follows conjugation of ubiquitin to a conserved cysteine residue of UBC homologues. TSG101 is one of several UBC h43 genes
ubiquitin thiolesterase activity, IEA40 genes
ubiquitin conjugating enzyme activity, IEA35 genes
UPF0242, Uncharacterised protein family (UPF0242)29 genes
ubiquitin-dependent protein catabolism, TAS25 genes
UDPGT, UDP-glucoronosyl and UDP-glucosyl transferase24 genes
ubiquitin conjugating enzyme activity, TAS21 genes
UBA, UBA/TS-N domain. This small domain is composed of three alpha helices. This family includes the previously defined UBA and TS-N domains. The UBA-domain (ubiquitin associated domain) is a novel sequence motif found in several proteins havi19 genes
ubiquitin-protein ligase activity, TAS17 genes
ubiquitin-protein ligase activity, NAS15 genes
Ubie_methyltran, ubiE/COQ5 methyltransferase family13 genes
Utp14, Utp14 protein. This protein is found to be part of a large ribonucleoprotein complex containing the U3 snoRNA. Depletion of the Utp proteins impedes production of the 18S rRNA, indicating that they are part of the active pre-rRNA proces13 genes
ubiquitin ligase complex, NAS13 genes
UBX, UBX domain. Domain present in ubiquitin-regulatory proteins. Present in FAF1 and Shp1p12 genes
UPF0073, Uncharacterised protein family (Hly-III / UPF0073). Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It is not clear if all the members of this family 12 genes
uDENN, uDENN domain. This region is always found associated with pfam02141. It is predicted to form an all beta domain12 genes
UTP biosynthesis, IEA10 genes
UPAR_LY6, u-PAR/Ly-6 domain. This extracellular disulphide bond rich domain is related to pfam000879 genes
UPF0005, Uncharacterised protein family UPF00058 genes
ubiquitin-dependent protein catabolism, NAS8 genes
UvrD-helicase, UvrD/REP helicase. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. Some members h7 genes
Uteroglobin, Uteroglobin family. Uteroglobin is a homodimer of two identical 70 amino acid polypeptides linked by two disulphide bridges. The precise role of uteroglobin has still to be elucidated7 genes
ubiquitin ligase complex, TAS7 genes
U-box, U-box domain. This domain is related to the Ring finger pfam00097 but lacks the zinc binding residues6 genes
uridine kinase activity, IEA6 genes
UPF0020, Putative RNA methylase family UPF0020. This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains5 genes
UBACT, Repeat in ubiquitin-activating (UBA) protein5 genes
UPF0227, Uncharacterised protein family (UPF0227). Despite being classed as uncharacterised proteins, the members of this family are almost certainly enzymes that are distantly related to the pfam005615 genes
ubiquitin thiolesterase activity, TAS5 genes
ubiquitin-protein ligase activity, IDA4 genes
uracil DNA N-glycosylase activity, TAS4 genes
UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, TAS4 genes
UbiA, UbiA prenyltransferase family3 genes
UPP_synthetase, Putative undecaprenyl diphosphate synthase. Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase3 genes
UDPGP, UTP--glucose-1-phosphate uridylyltransferase. This family consists of UTP--glucose-1-phosphate uridylyltransferases, EC:2.7.7.9. Also known as UDP-glucose pyrophosphorylase (UDPGP) and Glucose-1-phosphate uridylyltransferase. UTP--gluco3 genes
UDG, Uracil DNA glycosylase superfamily3 genes
UPF0136, Uncharacterized protein family (UPF0136). This family of short membrane proteins are as yet uncharacterized3 genes
UPF0041, Uncharacterised protein family (UPF0041)3 genes
UMPH-1, Pyrimidine 5'-nucleotidase (UMPH-1). This family consists of several eukaryotic pyrimidine 5'-nucleotidase proteins. P5'N-1, also known as uridine monophosphate hydrolase-1 (UMPH-1), is a member of a large functional group of enzymes, 3 genes
UPF0240, Uncharacterised protein family (UPF0240)3 genes
ubiquitin activating enzyme activity, IEA3 genes
ubiquinone biosynthesis, IEA3 genes
ubiquinol-cytochrome-c reductase activity, IEA3 genes
ubiquinol-cytochrome-c reductase activity, NAS3 genes
UV protection, TAS3 genes
ubiquinol-cytochrome-c reductase complex (sensu Eukarya), IEA3 genes
uncoupling protein activity, TAS3 genes
U6 snRNA binding, NAS3 genes
UPF0004, Uncharacterized protein family UPF0004. This family is the N terminal half of proteins with a C-terminal half, which has been shown to be related to MiaB proteins. This domain is a nearly always found in conjunction with pfam04055 and2 genes
UPF0103, Protein of unknown function DUF52. This family contains members from all branches of life. The function of this protein is unknown2 genes
UCR_hinge, Ubiquinol-cytochrome C reductase hinge protein. The ubiquinol-cytochrome C reductase complex (cytochrome bc1 complex) is a respiratory multienzyme complex. This Pfam family represents the 'hinge' protein of the complex which is thou2 genes
UCR_TM, Ubiquinol cytochrome reductase transmembrane region. Each subunit of the cytochrome bc1 complex provides a single helix (this family) to make up the transmembrane region of the complex2 genes
UT, Urea transporter. Members of this family transport urea across membranes. The family includes a bacterial homologue2 genes
UPF0172, Uncharacterised protein family (UPF0172)2 genes
UPF0197, Uncharacterized protein family (UPF0197). This family of proteins is functionally uncharacterized2 genes
UPF0224, Uncharacterized protein family (UPF0224). This family of proteins is functionally uncharacterized2 genes
UPF0203, Uncharacterised protein family (UPF0203). This family of proteins is functionally uncharacterised2 genes
UPF0220, Uncharacterized protein family (UPF0220). This family of proteins is functionally uncharacterized2 genes
UDP-g_GGTase, UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase2 genes
UPF0258, Uncharacterised protein family (UPF0258)2 genes
urea cycle, IEA2 genes
urea cycle, NR2 genes
urea cycle, TAS2 genes
ubiquitin activating enzyme activity, TAS2 genes
ubiquitin conjugating enzyme activity, NR2 genes
UDP-galactose transporter activity, TAS2 genes
UDP-glucose metabolism, TAS2 genes
ubiquitin cycle, IDA2 genes
ubiquitin cycle, NAS2 genes
ubiquinone biosynthesis, TAS2 genes
ubiquinol-cytochrome-c reductase activity, TAS2 genes
UDP-glycosyltransferase activity, TAS2 genes
UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, NAS2 genes
urea transporter activity, TAS2 genes
urea transport, TAS2 genes
unconventional myosin, TAS2 genes
Usher, Fimbrial Usher protein. This protein is involved in biogenesis of gram negative bacterial pili1 genes
UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase family, central domain. The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to a1 genes
UPF0027, Uncharacterized protein family UPF00271 genes
UPF0016, Uncharacterized protein family UPF0016. This family contains integral membrane proteins of unknown function. Most members of the family contain two copies of a region that contains an EXGD motif. Each of these regions contains three p1 genes
UPF0023, Uncharacterized protein family UPF0023. This family is highly conserved in species ranging from archaea to vertebrates and plants. The family contains several Shwachman-Bodian-Diamond syndrome (SBDS) proteins from both mouse and human1 genes
Urocanase, Urocanase1 genes
UPF0029, Uncharacterized protein family UPF00291 genes
URO-D, Uroporphyrinogen decarboxylase (URO-D)1 genes
UPF0118, Domain of unknown function DUF20. This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function. It is not clear what source suggested that these proteins may be permeases and t1 genes
UPF0086, Domain of unknown function UPF0086. This family consists of several archaeal and eukaryotic proteins. The archaeal proteins are found to be expressed within ribosomal operons and several of the sequences are described as ribonuclease 1 genes
UPF0066, Uncharacterized protein family UPF00661 genes
UPF0099, Domain of unknown function UPF0099. This domain has no known function1 genes
UPF0054, Uncharacterized protein family UPF00541 genes
UCR_14kD, Ubiquinol-cytochrome C reductase complex 14kD subunit. The ubiquinol-cytochrome C reductase complex (cytochrome bc1 complex) is a respiratory multienzyme complex. This Pfam family represents the 14kD (or VI) subunit of the complex wh1 genes
UPF0061, Uncharacterized ACR, YdiU/UPF0061 family1 genes
UcrQ, UcrQ family. The ubiquinol-cytochrome C reductase complex (cytochrome bc1 complex) is a respiratory multienzyme complex. This family represents the 9.5 kDa subunit of the complex1 genes
U79_P34, HSV U79 / HCMV P34. This family represents herpes virus protein U79 and cytomegalovirus early phosphoprotein P34 (UL112)1 genes
UFD1, Ubiquitin fusion degradation protein UFD1. Post-translational ubiquitin-protein conjugates are recognised for degradation by the ubiquitin fusion degradation (UFD) pathway. Several proteins involved in this pathway have been identified. 1 genes
UPF0108, Uncharacterized protein family (UPF0108)1 genes
UPF0113, Uncharacterised protein family (UPF0113)1 genes
UPF0121, Uncharacterized protein family (UPF0121). Uncharacterized integral membrane protein family1 genes
UPF0171, Uncharacterized protein family (UPF0171)1 genes
UPF0139, Uncharacterised protein family (UPF0139)1 genes
UPF0184, Uncharacterized protein family (UPF0184)1 genes
UPF0185, Uncharacterized protein family (UPF0185). This family contains a number of small uncharacterized proteins including BM-0021 genes
UPF0131, Uncharacterised protein family (UPF0131). This family of proteins are uncharacterised, however BtrG is part of a butirosin-biosynthetic gene cluster from Bacillus circulans1 genes
UPF0183, Uncharacterised protein family (UPF0183). This family of proteins includes Lin-10 from C. elegans1 genes
UPF0160, Uncharacterized protein family (UPF0160). This family of proteins contains a large number of metal binding residues. The patterns are suggestive of a phosphoesterase function. The conserved DHH motif may mean this family is related to1 genes
UPF0120, Uncharacterised protein family (UPF0120). At least one member, Nco2p from yeast, is required for a late step in 60S subunit export from the nucleus. It has also been shown to co-precipitate with Nug1p, a nuclear GTPase also required f1 genes
UDPG_MGDP_dh_C, UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain. The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcoho1 genes
UDPG_MGDP_dh_N, UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain. The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcoho1 genes
Ubiq_cyt_C_chap, Ubiquinol-cytochrome C chaperone1 genes
Utp11, Utp11 protein. This protein is found to be part of a large ribonucleoprotein complex containing the U3 snoRNA. Depletion of the Utp proteins impedes production of the 18S rRNA, indicating that they are part of the active pre-rRNA proces1 genes
Utp12, Dip2/Utp12 Family. This domain is found at the C-terminus of proteins containing WD40 repeats. These proteins are part of the U3 ribonucleoprotein the yeast protein is called Utp12 or DIP21 genes
Upf2, Up-frameshift suppressor 2. Transcripts harbouring premature signals for translation termination are recognised and rapidly degraded by eukaryotic cells through a pathway known as nonsense-mediated mRNA decay. In Saccharomyces cerevisiae1 genes
Utp21, Utp21 specific WD40 associated putative domain. Utp21 is a subunit of U3 snoRNP, which is essential for synthesis of 18S rRNA1 genes
Uso1_p115_head, Uso1 / p115 like vesicle tethering protein, head region. Also known as General vesicular transport factor, Transcytosis associated protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-terminal1 genes
Uso1_p115_C, Uso1 / p115 like vesicle tethering protein, C terminal region. Also known as General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-termin1 genes
UNC-50, UNC-50 family. This family contains several eukaryotic transmembrane proteins which are related to the C. elegans protein UNC-501 genes
UPF0193, Uncharacterized protein family (UPF0193). This family of proteins is functionally uncharacterized1 genes
UMP1, Proteasome maturation factor UMP1. UMP1 is a short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex. UMP1 is required for the correct assembly and enzymatic activation of the proteasome1 genes
UCR_UQCRX_QCR9, Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like. The UQCRX/QCR9 protein is the 9/10 subunit of complex III, encoding a protein of about 7-kDa. Deletion of QCR9 results in the inability of cells to grow on grow on-fermentable 1 genes
UPF0239, Uncharacterised protein family (UPF0239)1 genes
Uroplakin_II, Uroplakin II. This family contains uroplakin II, which is approximately 180 residues long and seems to be restricted to mammals. Uroplakin II is an integral membrane protein, and is one of the components of the apical plaques of 1 genes
urea cycle, NAS1 genes
urotensin II receptor activity, IEA1 genes
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity, IEA1 genes
UDP-N-acetylglucosamine diphosphorylase activity, TAS1 genes
UDP-glucose 4-epimerase activity, NR1 genes
UDP-glucose 6-dehydrogenase activity, TAS1 genes
UDP-glucose:glycoprotein glucosyltransferase activity, TAS1 genes
UTP-hexose-1-phosphate uridylyltransferase activity, IEA1 genes
UTP-hexose-1-phosphate uridylyltransferase activity, TAS1 genes
UTP-glucose-1-phosphate uridylyltransferase activity, TAS1 genes
ubiquitin activating enzyme activity, NR1 genes
ubiquitin conjugating enzyme activity, NAS1 genes
ubiquitin-protein ligase activity, NR1 genes
ubiquitin-specific protease activity, TAS1 genes
uridine kinase activity, TAS1 genes
uridine phosphorylase activity, IEA1 genes
uridine phosphorylase activity, TAS1 genes
uroporphyrinogen-III synthase activity, IEA1 genes
uroporphyrinogen decarboxylase activity, IEA1 genes
uroporphyrinogen decarboxylase activity, TAS1 genes
UDP-N-acetylglucosamine transporter activity, TAS1 genes
UDP-N-acetylgalactosamine transporter activity, NAS1 genes
UDP-N-acetylglucosamine metabolism, IEA1 genes
UDP-N-acetylglucosamine metabolism, TAS1 genes
UDP-N-acetylglucosamine biosynthesis, TAS1 genes
UDP-glucuronate biosynthesis, TAS1 genes
uracil catabolism, NAS1 genes
UMP biosynthesis, TAS1 genes
UDP catabolism, IDA1 genes
ubiquitin-dependent protein catabolism, NR1 genes
ubiquitin cycle, TAS1 genes
uroporphyrinogen III biosynthesis, TAS1 genes
unfolded protein response, positive regulation of target gene transcription, TAS1 genes
ultradian rhythm, IDA1 genes
UDP-glucose-hexose-1-phosphate uridylyltransferase activity, IEA1 genes
UDP-galactose-glucosylceramide beta-1,4-galactosyltransferase activity, TAS1 genes
ubiquitin-specific protease 5 activity, TAS1 genes
ubiquitin-like activating enzyme activity, TAS1 genes
UDP-N-acetylglucosamine 2-epimerase activity, TAS1 genes
UDP-sugar diphosphatase activity, IEA1 genes
unidimensional cell growth, IMP1 genes
ubiquinol-cytochrome-c reductase complex (sensu Eukarya), NAS1 genes
ubiquinol-cytochrome-c reductase complex (sensu Eukarya), TAS1 genes
uridine nucleotide receptor activity, TAS1 genes
urea transporter activity, IEA1 genes
uncoupling protein activity, NR1 genes
UDP-galactose transport, TAS1 genes
UDP-N-acetylglucosamine transport, TAS1 genes
UDP-N-acetylgalactosamine transport, NAS1 genes
urea transport, IEA1 genes
urocanate hydratase activity, IEA1 genes
unconventional myosin, NAS1 genes
ubiquitin-like-protein ligase activity, IDA1 genes
ubiquitin-like-protein ligase activity, TAS1 genes
U-plasminogen activator receptor activity, IEA1 genes
ubiquitin binding, IDA1 genes
ubiquitin binding, NAS1 genes
UDP-activated nucleotide receptor activity, NAS1 genes
uridine diphosphatase activity, IDA1 genes
unmethylated CpG binding, IDA1 genes
urothelial cell proliferation, IDA1 genes
AS3D: Alternative Splicing Structural Genomics Projects
CARB/UMBI