| zinc ion binding, IEA | 990 genes |
| zf-C3HC4, Zinc finger, C3HC4 type (RING finger). The C3HC4 type zinc-finger (RING finger) is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X( | 127 genes |
| zf-C2H2, Zinc finger, C2H2 type. The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6) | 74 genes |
| zinc ion binding, NAS | 70 genes |
| zinc ion binding, TAS | 57 genes |
| zf-C4, Zinc finger, C4 type (two domains). In nearly all cases, this is the DNA binding domain of a nuclear hormone receptor. The alignment contains two Zinc finger domains that are too dissimilar to be aligned with each other | 46 genes |
| zf-B_box, B-box zinc finger | 41 genes |
| Zn_carbOpept, Zinc carboxypeptidase | 23 genes |
| zf-DHHC, DHHC zinc finger domain. This domain is also known as NEW1. This domain is predicted to be a zinc binding domain. The function of this domain is unknown, but it has been predicted to be involved in protein-protein or protein-DNA inter | 23 genes |
| Zona_pellucida, Zona pellucida-like domain | 19 genes |
| ZZ, Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300. ZZ in dystrophin binds calmodulin Putative zinc finger; binding not yet shown | 15 genes |
| zf-MYND, MYND finger | 15 genes |
| Zip, ZIP Zinc transporter. The ZIP family consists of zinc transport proteins and many putative metal transporters. The main contribution to this family is from the Arabidopsis thaliana ZIP protein family these proteins are responsible for zin | 15 genes |
| zf-CCCH, Zinc finger C-x8-C-x5-C-x3-H type (and similar) | 13 genes |
| zf-UBP, Zn-finger in ubiquitin-hydrolases and other protein | 13 genes |
| zf-RanBP, Zn-finger in Ran binding protein and others | 10 genes |
| ZU5, ZU5 domain. Domain present in ZO-1 and Unc5-like netrin receptors Domain of unknown function | 10 genes |
| zf-CXXC, CXXC zinc finger. This domain contains eight conserved cysteine residues that bind to zinc. The CXXC domain is found in proteins that methylate cytosine, proteins that bind to methyl cytosine and HRX related proteins | 9 genes |
| zf-C2HC, Zinc finger, C2HC type. This is a DNA binding zinc finger domain | 6 genes |
| zf-TRAF, TRAF-type zinc finger | 6 genes |
| zf-MIZ, MIZ zinc finger | 6 genes |
| zf-Tim10_DDP, Tim10/DDP family zinc finger. Putative zinc binding domain with four conserved cysteine residues. This domain is found in the human disease protein. Members of this family such as Tim9 and Tim10 are involved in mitochondrial prot | 6 genes |
| zf-Sec23_Sec24, Sec23/Sec24 zinc finger. COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the | 6 genes |
| zinc ion binding, ISS | 6 genes |
| zf-A20, A20-like zinc finger. A20- (an inhibitor of cell death)-like zinc fingers. The zinc finger mediates self-association in A20. These fingers also mediate IL-1-induced NF-kappa B activation | 5 genes |
| zf-UBR1, Putative zinc finger in N-recognin | 5 genes |
| zf-C5HC2, C5HC2 zinc finger. Predicted zinc finger with eight potential zinc ligand binding residues. This domain is found in Jumonji. This domain may have a DNA binding function | 5 genes |
| zf-HIT, HIT zinc finger. This presumed zinc finger contains up to 6 cysteine residues that could coordinate zinc. The domain is named after the HIT protein. This domain is also found in the Thyroid receptor interacting protein 3 (TRIP-3) that | 5 genes |
| zf-GRF, GRF zinc finger. This presumed zinc binding domain is found in a variety of DNA-binding proteins. It seems likely that this domain is involved in nucleic acid binding. It is named GRF after three conserved residues in the centre of the | 5 genes |
| zf-BED, BED zinc finger | 4 genes |
| zf-MYM, MYM-type Zinc finger. MYM-type zinc fingers were identified in MYM family proteins. Human zinc finger protein 261 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Human zinc finger p | 4 genes |
| zinc ion transport, IEA | 4 genes |
| zf-AN1, AN1-like Zinc finger. Zinc finger at the C-terminus of An1, a ubiquitin-like protein in Xenopus laevis. The following pattern describes the zinc finger. C-X2-C-X(9-12)-C-X(1-2)-C-X4-C-X2-H-X5-H-X-C Where X can be any amino acid, and nu | 3 genes |
| Zein, Zein seed storage protein. Zeins are seed storage proteins. They are unusually rich in glutamine, proline, alanine, and leucine residues and their sequences show a series of tandem repeats | 3 genes |
| Zfx_Zfy_act, Zfx / Zfy transcription activation region. Zfx and Zfy are transcription factors implicated in mammalian sex determination. This region is found N terminal to multiple copies of a C2H2 Zinc finger (pfam00096). This region has been | 3 genes |
| zf-nanos, Nanos RNA binding domain. This family consists of several conserved novel zinc finger domains found in the eukaryotic proteins Nanos and Xcat-2. In Drosophila melanogaster, Nanos functions as a localised determinant of posterior patt | 3 genes |
| zinc ion binding, IDA | 3 genes |
| zf-CCHC, Zinc knuckle. The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also co | 2 genes |
| zf-PARP, Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region. Poly(ADP-ribose) polymerase is an important regulatory component of the cellular response to DNA damage. The amino-terminal region of Poly(ADP-ribose) polymerase consists of | 2 genes |
| zf-TAZ, TAZ zinc finger. The TAZ2 domain of CBP binds to other transcription factors such as the p53 tumour suppressor protein, E1A oncoprotein, MyoD, and GATA-1 | 2 genes |
| zf-CSL, CSL zinc finger. This probable zinc binding motif contains four cysteines that probably chelate zinc. This domain is often found associated with a pfam00226 domain. The molecular function of these proteins is uncertain. This domain is | 2 genes |
| Zot, Zonular occludens toxin (Zot). This family consists of bacterial and viral proteins which are very similar to the Zonular occludens toxin (Zot). Zot is elaborated by bacteriophages present in toxigenic strains of Vibrio cholerae. Zot is a | 2 genes |
| zf-U1, U1 zinc finger. This family consists of several U1 small nuclear ribonucleoprotein C (U1-C) proteins. The U1 small nuclear ribonucleoprotein (U1 snRNP) binds to the pre-mRNA 5' splice site (ss) at early stages of spliceosome assembly. R | 2 genes |
| Zw10, Centromere/kinetochore Zw10. Zw10 and rough deal proteins are both required for correct metaphase check-pointing during mitosis. These proteins bind to the centromere/kinetochore | 2 genes |
| zinc ion transporter activity, TAS | 2 genes |
| zf-C4_Topoisom, Topoisomerase DNA binding C4 zinc finger | 1 genes |
| z-alpha, Adenosine deaminase z-alpha domain. This family consists of the N-terminus and thus the z-alpha domain of double-stranded RNA-specific adenosine deaminase (ADAR), an RNA- editing enzyme. The z-alpha domain is a Z-DNA binding domain, a | 1 genes |
| zf-ZPR1, ZPR1 zinc-finger domain. The zinc-finger protein ZPR1 is ubiquitous among eukaryotes. It is indeed known to be an essential protein in yeast. In quiescent cells, ZPR1 is localised to the cytoplasm. But in proliferating cells treated w | 1 genes |
| zf-NPL4, NPL4 family, putative zinc binding region. The HRD4 gene was identical to NPL4, a gene previously implicated in nuclear transport. Using a diverse set of substrates and direct ubiquitination assays, analysis revealed that HRD4/NPL4 is | 1 genes |
| zf-DNL, DNL zinc finger. This short presumed domain probably binds to zinc. It is found in a number of eukaryotic proteins of unknown function. The domain is named after a short C-terminal motif of D(N/H)L | 1 genes |
| zf-CHY, CHY zinc finger. This family of domains are likely to bind to zinc ions. They contain many conserved cysteine and histidine residues. We have named this domain after the N-terminal motif CXHY. This domain can be found in isolation in s | 1 genes |
| zf-piccolo, Piccolo Zn-finger. This (predicted) Zinc finger is found in the bassoon and piccolo proteins. There are eight conserved cysteines, suggesting that it coordinates two zinc ligands | 1 genes |
| Zf-C2HC5, Putative zinc finger motif, C2HC5-type. This zinc finger appears to be common in activating signal cointegrator 1/thyroid receptor interacting protein 4 | 1 genes |
| zf-FPG_IleRS, Zinc finger found in FPG and IleRS. This zinc binding domain is found at the C-terminus of isoleucyl tRNA synthetase and the enzyme Formamidopyrimidine-DNA glycosylase EC:3.2.2.23 | 1 genes |
| zeta DNA polymerase activity, TAS | 1 genes |
| zinc ion transporter activity, IDA | 1 genes |
| zonula adherens, TAS | 1 genes |
| zinc ion transport, IDA | 1 genes |
| zinc ion transport, TAS | 1 genes |
| zinc ion homeostasis, IDA | 1 genes |
| zinc ion binding, NR | 1 genes |
| zinc porter activity, TAS | 1 genes |
| zeta DNA polymerase complex, NR | 1 genes |
| Z disc, NAS | 1 genes |
| Z disc, TAS | 1 genes |
AS3D Human
