AS3D Human


We have recently updated our webserver and apologize for any inconvenience this might cause.

Quick Find
Search

Suggestions:

Gene Lists
· AS3D Targets
· Alternative Splcing
· A · B · C · D · E · F · G · H · I · J · K · L · M · N · O · P · Q · R · S · T · U · V · W · X · Y · Z All

Human Gene Lists R
regulation of transcription, DNA-dependent, IEA1135 genes
receptor activity, IEA515 genes
rhodopsin-like receptor activity, IEA251 genes
RRM_1, RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain). The RRM motif is probably diagnostic of an RNA binding protein. RRMs are found in a variety of RNA binding proteins, including various hnRNP proteins, proteins implicated in regul219 genes
Ras, Ras family. Includes sub-families Ras, Rab, Rac, Ral, Ran, Rap Ypt1 and more. Shares P-loop motif with GTP_EFTU, arf and myosin_head. See pfam00009 pfam00025, pfam00063. The high cutoff is so high to avoid overlaps with related families181 genes
RNA binding, IEA181 genes
regulation of transcription, DNA-dependent, NAS162 genes
regulation of transcription from Pol II promoter, TAS141 genes
RNA binding, TAS129 genes
ribosome, IEA111 genes
RNA polymerase II transcription factor activity, TAS105 genes
regulation of cell cycle, TAS96 genes
receptor activity, TAS92 genes
RhoGAP, RhoGAP domain. GTPase activator proteins towards Rho/Rac/Cdc42-like small GTPases70 genes
RhoGEF, RhoGEF domain. Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that pfam00169 domains invariably occur C-terminal to RhoGEF/DH domains69 genes
regulation of transcription, DNA-dependent, TAS65 genes
regulation of cell cycle, IEA50 genes
RNA splicing, TAS45 genes
regulation of apoptosis, IEA45 genes
receptor binding, TAS41 genes
Reprolysin, Reprolysin (M12B) family zinc metalloprotease. The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. Members of this family are also known as adamalysins. Most members of this fami40 genes
response to stress, TAS39 genes
RA, Ras association (RalGDS/AF-6) domain. RasGTP effectors (in cases of AF6, canoe and RalGDS); putative RasGTP effectors in other cases. Recent evidence (not yet in MEDLINE) shows that some RA domains do NOT bind RasGTP. Predicted structure s34 genes
RGS, Regulator of G protein signaling domain. RGS family members are GTPase-activating proteins for heterotrimeric G-protein alpha-subunits32 genes
regulation of cell growth, IEA32 genes
regulation of cyclin dependent protein kinase activity, TAS31 genes
RasGEF, RasGEF domain. Guanine nucleotide exchange factor for Ras-like small GTPases26 genes
response to virus, TAS26 genes
regulation of cell cycle, NR25 genes
RNA processing, IEA25 genes
ribonucleoprotein complex, IEA25 genes
Ribosomal_S2, Ribosomal protein S223 genes
Ribosomal_L7Ae, Ribosomal protein L7Ae/L30e/S12e/Gadd45 family. This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Rib23 genes
RNA_pol_delta, DNA-directed RNA polymerase delta subunit. The delta protein is a dispensable subunit of Bacillus subtilis RNA polymerase (RNAP) that has major effects on the biochemical properties of the purified enzyme. In the presence of del23 genes
RNA processing, TAS23 genes
regulation of heart rate, TAS23 genes
Rhodanese, Rhodanese-like domain. Rhodanese has an internal duplication. This Pfam represents a single copy of this duplicated domain. The domain is found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydr22 genes
regulation of cell growth, NAS21 genes
receptor mediated endocytosis, TAS21 genes
RNA binding, NAS19 genes
regulation of translational initiation, TAS19 genes
regulation of G-protein coupled receptor protein signaling pathway, TAS19 genes
Ribosomal_L23, Ribosomal protein L2318 genes
Ribosomal_L21e, Ribosomal protein L21e18 genes
Rho protein signal transduction, TAS18 genes
RasGAP, GTPase-activator protein for Ras-like GTPase. All alpha-helical domain that accelerates the GTPase activity of Ras, thereby "switching" it into an "off" position17 genes
receptor signaling protein activity, TAS17 genes
RAS protein signal transduction, TAS17 genes
RUN, RUN domain. This domain is present in several proteins that are linked to the functions of GTPases in the Rap and Rab families. They could hence play important roles in multiple Ras-like GTPase signaling pathways16 genes
response to oxidative stress, TAS16 genes
receptor activity, NR15 genes
Ribosomal_L10e, Ribosomal L1014 genes
Ribosomal_S26e, Ribosomal protein S26e13 genes
RNA polymerase II transcription factor activity, enhancer binding, TAS13 genes
rRNA processing, IEA13 genes
response to oxidative stress, IEA13 genes
regulation of blood pressure, TAS13 genes
response to pest, pathogen or parasite, TAS13 genes
response to drug, TAS13 genes
RnaseA, Pancreatic ribonuclease. Ribonucleases. Members include pancreatic RNAase A and angiogenins. Structure is an alpha+beta fold -- long curved beta sheet and three helices12 genes
Ribosomal_L31e, Ribosomal protein L31e12 genes
Reo_sigma1, Reovirus viral attachment protein sigma 1. This family consists of the reovirus sigma 1 hemagglutinin, cell attachment protein. This glycoprotein is a minor capsid protein and also determines the serotype-specific humoral immune re12 genes
RPH3A_effector, Rabphilin-3A effector domain. This is a family of proteins involved in protein transport in synaptic vesicles. Rabphilin-3A has been shown to contact Rab3A, a small G protein important in neurotransmitter release, in two distin12 genes
Ribosomal_S5_C, Ribosomal protein S5, C-terminal domain12 genes
RNA polymerase II transcription factor activity, NR12 genes
response to nutrients, TAS12 genes
respiratory gaseous exchange, TAS12 genes
Rap_GAP, Rap/ran-GAP11 genes
RNA binding, NR11 genes
RNA catabolism, TAS11 genes
regulation of translation, TAS11 genes
response to stress, IDA11 genes
response to wounding, TAS11 genes
response to pest, pathogen or parasite, IEA11 genes
response to pathogenic bacteria, TAS11 genes
receptor signaling complex scaffold activity, NAS11 genes
RVT, Reverse transcriptase (RNA-dependent DNA polymerase). A reverse transcriptase gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. Reverse transcriptases occur in a variety of mobile elements, including 10 genes
RHD, Rel homology domain (RHD). Proteins containing the Rel homology domain (RHD) are eukaryotic transcription factors. The RHD is composed of two structural domains. This is the N-terminal domain that is similar to that found in P53. The C-te10 genes
RasGEF_N, Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif. A subset of guanine nucleotide exchange factor for Ras-like small GTPases appear to possess this motif/domain N-terminal to the RasGef (Cdc25-like) domain10 genes
RAP1, Rhoptry-associated protein 1 (RAP-1). This family consists of several rhoptry-associated protein 1 (RAP-1) sequences which appear to be specific to Plasmodium falciparum10 genes
receptor activity, IDA10 genes
receptor activity, NAS10 genes
receptor signaling protein activity, NR10 genes
regulation of transcription, DNA-dependent, IDA10 genes
rRNA processing, TAS10 genes
RNA polymerase II transcription mediator activity, IDA10 genes
Ribosomal_L22, Ribosomal protein L22p/L17e. This family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes9 genes
Ribosomal_S5, Ribosomal protein S5, N-terminal domain9 genes
Ribosomal_L13, Ribosomal protein L139 genes
Ran_BP1, RanBP1 domain9 genes
Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TG9 genes
Radial_spoke, Radial spokehead-like protein. This family includes the radial spoke head proteins RSP4 and RSP6 from Chlamydomonas reinhardtii, and several eukaryotic homologues, including mammalian RSHL1, the protein product of a familial cili9 genes
Rho GTPase activator activity, TAS9 genes
regulation of transcription from Pol II promoter, NR9 genes
regulation of mitosis, TAS9 genes
regulation of transcription, NAS9 genes
RCC1, Regulator of chromosome condensation (RCC1)8 genes
Ribosomal_60s, 60s Acidic ribosomal protein. This family includes archaebacterial L12, eukaryotic P0, P1 and P28 genes
Ribosomal_S3Ae, Ribosomal S3Ae family8 genes
RIIa, Regulatory subunit of type II PKA R-subunit8 genes
RFX_DNA_binding, RFX DNA-binding domain. RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as eit8 genes
Radical_SAM, Radical SAM superfamily8 genes
RIB43A, RIB43A. This family consists of several RIB43A-like eukaryotic proteins. Ciliary and flagellar microtubules contain a specialised set of protofilaments, termed ribbons, that are composed of tubulin and several associated proteins. RIB48 genes
RR_TM4-6, Ryanodine Receptor TM 4-6. This region covers TM regions 4-6 of the ryanodine receptor 1 family8 genes
regulation of cell cycle, NAS8 genes
RNA binding, IDA8 genes
regulation of translation, IEA8 genes
response to stress, NAS8 genes
regulation of blood pressure, NAS8 genes
regulation of transcription, IEA8 genes
Ricin_B_lectin, QXW lectin repeat7 genes
Ribosomal_L44, Ribosomal protein L447 genes
Recep_L_domain, Receptor L domain. The L domains from these receptors make up the bilobal ligand binding site. Each L domain consists of a single-stranded right hand beta-helix. This Pfam entry is missing the first 50 amino acid residues of th7 genes
RNase_PH, 3' exoribonuclease family, domain 1. This family includes 3'-5' exoribonucleases. Ribonuclease PH contains a single copy of this domain, and removes nucleotide residues following the -CCA terminus of tRNA. Polyribonucleotide nucleoti7 genes
R3H, R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA7 genes
Ribosomal_L32e, Ribosomal protein L32. This family includes ribosomal protein L32 from eukaryotes and archaebacteria7 genes
Rad17, Rad17 cell cycle checkpoint protein7 genes
Reo_sigmaC, Reovirus sigma C capsid protein7 genes
RWD, RWD domain. This domain was identified in WD40 repeat proteins and Ring finger domain proteins. The function of this domain is unknown7 genes
RNA helicase activity, TAS7 genes
Rho guanyl-nucleotide exchange factor activity, TAS7 genes
receptor binding, NR7 genes
regulation of muscle contraction, TAS7 genes
retinol binding, IEA7 genes
ribonucleoprotein complex, TAS7 genes
Ribosomal_L30, Ribosomal protein L30p/L7e. This family includes prokaryotic L30 and eukaryotic L76 genes
Ribosomal_S17e, Ribosomal S176 genes
Ribosomal_L18p, Ribosomal L18p/L5e family. This family includes ribosomal proteins from the large subunit. This family includes L18 from bacteria and L5 from eukaryotes. It has been shown for one member that the amino terminal 93 amino acids a6 genes
RYDR_ITPR, RIH domain. The RIH (RyR and IP3R Homology) domain is an extracellular domain from two types of calcium channels. This region is found in the ryanodine receptor and the inositol-1,4,5- trisphosphate receptor. This domain may form a 6 genes
Ribosomal_L18ae, Ribosomal L18ae protein family6 genes
Ribosomal_L22e, Ribosomal L22e protein family6 genes
RBD, Raf-like Ras-binding domain6 genes
Ribosomal_L11_N, Ribosomal protein L11, N-terminal domain. The N-terminal domain of Ribosomal protein L11 adopts an alpha/beta fold and is followed by the RNA binding C-terminal domain6 genes
regulation of cell cycle, ISS6 genes
receptor signaling protein tyrosine kinase activity, TAS6 genes
receptor signaling protein activity, IEA6 genes
RNA elongation, IEA6 genes
ribosome biogenesis, IEA6 genes
RAS protein signal transduction, NAS6 genes
response to biotic stimulus, IEA6 genes
response to toxin, TAS6 genes
regulation of signal transduction, IEA6 genes
rRNA binding, IEA6 genes
regulation of apoptosis, NAS6 genes
Ribosomal_S19, Ribosomal protein S195 genes
Ribosomal_L14, Ribosomal protein L14p/L23e5 genes
Ribosomal_L11, Ribosomal protein L11, RNA binding domain5 genes
Ribosomal_S8, Ribosomal protein S85 genes
Ribosomal_S11, Ribosomal protein S115 genes
RF-1, Peptidyl-tRNA hydrolase domain. This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. The domain cont5 genes
Ribosomal_L1, Ribosomal protein L1p/L10e family. This family includes prokaryotic L1 and eukaryotic L105 genes
Ribosomal_S4e, Ribosomal family S4e5 genes
RNA_pol_L, RNA polymerase Rpb3/Rpb11 dimerisation domain. The two eukaryotic subunits Rpb3 and Rpb11 dimerise to from a platform onto which the other subunits of the RNA polymerase assemble (D/L in archaea). The prokaryotic equivalent to the R5 genes
Ribosomal_S8e, Ribosomal protein S8e5 genes
Reticulon, Reticulon. Reticulon, also know as neuroendocrine-specific protein (NSP), is a protein of unknown function which associates with the endoplasmic reticulum. This family represents the C-terminal domain of the three reticulon isoforms5 genes
RNase_PH_C, 3' exoribonuclease family, domain 2. This family includes 3'-5' exoribonucleases. Ribonuclease PH contains a single copy of this domain, and removes nucleotide residues following the -CCA terminus of tRNA. Polyribonucleotide nucleo5 genes
RNA cap binding, TAS5 genes
RNA polymerase III transcription factor activity, TAS5 genes
RNA binding, ISS5 genes
ribonuclease P activity, TAS5 genes
ribonuclease activity, TAS5 genes
receptor binding, IEA5 genes
ribosome, NAS5 genes
ribosome, TAS5 genes
regulation of transcription from Pol III promoter, TAS5 genes
RNA elongation from Pol II promoter, TAS5 genes
regulation of translation, NAS5 genes
regulation of pH, IEA5 genes
regulation of striated muscle contraction, TAS5 genes
response to stress, NR5 genes
rhythmic behavior, IEA5 genes
RNA splicing, NAS5 genes
RAN protein binding, TAS5 genes
response to virus, NAS5 genes
regulation of cell adhesion, IEA5 genes
regulation of cell migration, IEA5 genes
regulation of cell proliferation, ISS5 genes
regulation of transcription, ISS5 genes
regulation of embryonic development, IEA5 genes
RecA, recA bacterial DNA recombination protein4 genes
Ribosomal_L3, Ribosomal protein L34 genes
Ribosomal_S9, Ribosomal protein S9/S16. This family includes small ribosomal subunit S9 from prokaryotes and S16 from eukaryotes4 genes
RrnaAD, Ribosomal RNA adenine dimethylase4 genes
rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the cen4 genes
RNB, RNB-like protein. The function of this region of similarity is uncertain4 genes
RNA_helicase, RNA helicase. This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses4 genes
Ribosomal_S18, Ribosomal protein S184 genes
Ribosomal_L36e, Ribosomal protein L36e4 genes
Ribosomal_L6e, Ribosomal protein L6e4 genes
RIO1, RIO1 family. This family of proteins are related to eukaryotic type protein kinases4 genes
Ribosomal_L24e, Ribosomal protein L24e4 genes
Ribosomal_S21e, Ribosomal protein S21e4 genes
Ribosomal_S7e, Ribosomal protein S7e4 genes
Ribosomal_S27e, Ribosomal protein S274 genes
Ribosomal_L29e, Ribosomal L29e protein family4 genes
REJ, REJ domain. The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor for egg jelly. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains.4 genes
Ribosomal_S25, S25 ribosomal protein4 genes
Rota_VP2, Rotavirus VP2 protein. Rotavirus particles consist of three concentric proteinaceous capsid layers. The innermost capsid (core) is made of VP2. The genomic RNA and the two minor proteins VP1 and VP3 are encapsidated within this layer4 genes
RNA polymerase I transcription factor activity, TAS4 genes
retinol dehydrogenase activity, TAS4 genes
receptor signaling protein activity, NAS4 genes
Ras GTPase activator activity, TAS4 genes
Rho GTPase activator activity, NAS4 genes
receptor binding, NAS4 genes
regulation of transcription, DNA-dependent, ISS4 genes
regulation of transcription, DNA-dependent, NR4 genes
regulation of transcription from Pol I promoter, TAS4 genes
rRNA processing, NAS4 genes
regulation of translation, IDA4 genes
regulation of translational initiation, IEA4 genes
regulation of muscle contraction, NR4 genes
regulation of smooth muscle contraction, TAS4 genes
response to DNA damage stimulus, TAS4 genes
receptor guanylyl cyclase signaling pathway, TAS4 genes
regulation of blood pressure, IEA4 genes
regulation of blood pressure, NR4 genes
ribulose bisphosphate carboxylase complex, IEA4 genes
response to metal ion, TAS4 genes
ribulose-bisphosphate carboxylase activity, IEA4 genes
regulation of Wnt receptor signaling pathway, NAS4 genes
regulation of cell adhesion, NAS4 genes
regulation of actin filament polymerization, IEA4 genes
regulation of cell proliferation, TAS4 genes
regulation of GTPase activity, IEA4 genes
regulation of cell differentiation, ISS4 genes
regulation of cell differentiation, NAS4 genes
regulation of neuron differentiation, NAS4 genes
regulation of protein kinase activity, ISS4 genes
regulation of development, IEA4 genes
regulation of liquid surface tension, IEA4 genes
RnaseH, RNase H. RNase H digests the RNA strand of an RNA/DNA hybrid. Important enzyme in retroviral replication cycle, and often found as a domain associated with reverse transcriptases. Structure is a mixed alpha+beta fold with three a/b/a l3 genes
Ribosomal_S12, Ribosomal protein S123 genes
Ribonuc_red_sm, Ribonucleotide reductase, small chain3 genes
Ribosomal_S10, Ribosomal protein S10p/S20e. This family includes small ribosomal subunit S10 from prokaryotes and S20 from eukaryotes3 genes
Rieske, Rieske [2Fe-2S] domain. The rieske domain has a [2Fe-2S] centre. Two conserved cysteines that one Fe ion while the other Fe ion is coordinated by two conserved histidines3 genes
RNA_pol_Rpb2_6, RNA polymerase Rpb2, domain 6. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
Ribosomal_L4, Ribosomal protein L4/L1 family. This family includes Ribosomal L4/L1 from eukaryotes and archaebacteria and L4 from eubacteria. L4 from yeast has been shown to bind rRNA3 genes
RNA_pol_Rpb1_2, RNA polymerase Rpb1, domain 2. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
Ribosomal_L15e, Ribosomal L153 genes
Ribosomal_L18e, Eukaryotic ribosomal protein L183 genes
Ribosomal_L29, Ribosomal L29 protein3 genes
Ribosomal_L39, Ribosomal L39 protein3 genes
Runt, Runt domain3 genes
Ribonuc_L-PSP, Endoribonuclease L-PSP. Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regula3 genes
Ribosomal_S6e, Ribosomal protein S6e3 genes
Renal_dipeptase, Renal dipeptidase3 genes
Ribosomal_L19e, Ribosomal protein L19e3 genes
Ribosomal_S27, Ribosomal protein S27a. This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesised as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of th3 genes
RB_B, Retinoblastoma-associated protein B domain. The crystal structure of the Rb pocket bound to a nine-residue E7 peptide containing the LxCxE motif, shared by other Rb-binding viral and cellular proteins, shows that the LxCxE peptide binds 3 genes
RB_A, Retinoblastoma-associated protein A domain. This domain has the cyclin fold as predicted3 genes
Ribosomal_L37e, Ribosomal protein L37e. This family includes ribosomal protein L37 from eukaryotes and archaebacteria. The family contains many conserved cysteines and histidines suggesting that this protein may bind to zinc3 genes
Reeler, Reeler domain3 genes
RyR, RyR domain. This domain is called RyR for Ryanodine receptor. The domain is found in four copies in the ryanodine receptor. The function of this domain is unknown3 genes
Rho_GDI, RHO protein GDP dissociation inhibitor3 genes
RPE65, Retinal pigment epithelial membrane protein. This family represents a retinal pigment epithelial membrane receptor which is abundantly expressed in retinal pigment epithelium, and binds plasma retinal binding protein. The family also in3 genes
Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat 3 genes
Retrotrans_gag, Retrotransposon gag protein. Gag or Capsid-like proteins from LTR retrotransposons. There is a central motif QGXXEXXXXXFXXLXXH that is common to Retroviridae gag-proteins, but is poorly conserved3 genes
RasGAP_C, RasGAP C-terminus3 genes
Ribosomal_L6e_N, Ribosomal protein L6, N-terminal domain3 genes
RNA_pol_Rpb2_7, RNA polymerase Rpb2, domain 7. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
RNA_pol_Rpb2_2, RNA polymerase Rpb2, domain 2. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
RNA_pol_Rpb2_1, RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerase3 genes
RNA_pol_Rpb2_3, RNA polymerase Rpb2, domain 3. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
RNA_pol_Rpb2_5, RNA polymerase Rpb2, domain 5. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
RFX1_trans_act, RFX1 transcription activation region. The RFX family is a family of winged-helix DNA binding proteins. RFX1 is a regulatory factor essential for expression of MHC class II genes. This region is to found N terminal to the RFX DN3 genes
RAMP, Receptor activity modifying family. The calcitonin-receptor-like receptor can function as either a calcitonin-gene-related peptide or an adrenomedullin receptor. The receptors function is modified by receptor-activity-modifying protein o3 genes
RNA_pol_Rpb1_3, RNA polymerase Rpb1, domain 3. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
RNA_pol_Rpb1_1, RNA polymerase Rpb1, domain 1. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
RNA_pol_Rpb1_5, RNA polymerase Rpb1, domain 5. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
RNA_pol_Rpb1_4, RNA polymerase Rpb1, domain 4. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera3 genes
RRN3, RNA polymerase I specific transcription initiation factor RRN3. This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription 3 genes
Ribonuc_2-5A, Ribonuclease 2-5A. This domain is a endoribonuclease. Specifically it cleaves an intron from Hac1 mRNA in humans, which causes it to be much more efficiently translated3 genes
RGM_N, Repulsive guidance molecule (RGM) N-terminus. This family consists of the N-terminal region of several mammalian and one bird sequence from Gallus gallus (Chicken). All of the mammalian proteins are hypothetical and have no known functi3 genes
regulation of DNA recombination, TAS3 genes
regulation of cyclin dependent protein kinase activity, NR3 genes
rRNA modification, IEA3 genes
rRNA (adenine-N6,N6-)-dimethyltransferase activity, IEA3 genes
regulation of cell growth, ISS3 genes
response to hypoxia, IDA3 genes
RNA polymerase II transcription factor activity, IEA3 genes
retinoic acid receptor activity, TAS3 genes
ribonuclease H activity, IEA3 genes
ribonuclease activity, IEA3 genes
ribose-phosphate diphosphokinase activity, IEA3 genes
retinoid-X receptor activity, TAS3 genes
Ras guanyl-nucleotide exchange factor activity, TAS3 genes
Rho guanyl-nucleotide exchange factor activity, NAS3 genes
Rho GDP-dissociation inhibitor activity, TAS3 genes
receptor binding, IPI3 genes
retinoid binding, TAS3 genes
regulation of translational initiation, NAS3 genes
regulation of translational termination, TAS3 genes
retrograde transport, Golgi to ER, NAS3 genes
response to DNA damage stimulus, IEA3 genes
response to oxidative stress, NR3 genes
regulation of mitosis, ISS3 genes
regulation of exit from mitosis, NAS3 genes
respiratory gaseous exchange, IEA3 genes
regulation of G-protein coupled receptor protein signaling pathway, NAS3 genes
RNA splicing, ISS3 genes
reduced folate carrier activity, IEA3 genes
rRNA methyltransferase activity, IEA3 genes
response to radiation, TAS3 genes
response to cold, TAS3 genes
response to wounding, NAS3 genes
regulation of signal transduction, NAS3 genes
response to organic substance, ISS3 genes
rhodopsin mediated signaling, TAS3 genes
regulator of G-protein signaling activity, NAS3 genes
RNA polymerase II transcription mediator activity, NAS3 genes
Ras interactor activity, NAS3 genes
regulation of calcium ion-dependent exocytosis, ISS3 genes
regulation of vasoconstriction, IEA3 genes
regulation of proteolysis and peptidolysis, NAS3 genes
regulation of cell migration, NAS3 genes
regulation of growth, NAS3 genes
regulation of cell proliferation, NAS3 genes
ribosome assembly, ISS3 genes
regulation of transcriptional preinitiation complex formation, ISS3 genes
regulation of RNA-nucleus export, ISS3 genes
Ribosomal_S7, Ribosomal protein S7p/S5e. This family contains ribosomal protein S7 from prokaryotes and S5 from eukaryotes2 genes
Ribosomal_L2, Ribosomal Proteins L2, RNA binding domain2 genes
Ribosomal_L16, Ribosomal protein L162 genes
Ribosomal_S15, Ribosomal protein S152 genes
Ribosomal_L6, Ribosomal protein L62 genes
Ribosomal_S17, Ribosomal protein S172 genes
Ribosomal_S13, Ribosomal protein S13/S18. This family includes ribosomal protein S13 from prokaryotes and S18 from eukaryotes2 genes
Ribosomal_L10, Ribosomal protein L102 genes
Ribonuclease_3, RNase3 domain2 genes
Rotamase, PPIC-type PPIASE domain. Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline2 genes
Ribosomal_L5_C, ribosomal L5P family C-terminus. This region is found associated with pfam002812 genes
Ribul_P_3_epim, Ribulose-phosphate 3 epimerase family. This enzyme catalyses the conversion of D-ribulose 5-phosphate into D-xylulose 5-phosphate2 genes
RNA_pol_A_bac, RNA polymerase Rpb3/RpoA insert domain. Members of this family include: alpha subunit from eubacteria alpha subunits from chloroplasts Rpb3 subunits from eukaryotes RpoD subunits from archaeal2 genes
RTC, RNA 3'-terminal phosphate cyclase. RNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the e2 genes
Ribosomal_L34e, Ribosomal protein L34e2 genes
Ribosomal_L13e, Ribosomal protein L13e2 genes
RRF, Ribosome recycling factor. The ribosome recycling factor (RRF / ribosome release factor) dissociates the ribosome from the mRNA after termination of translation, and is essential bacterial growth. Thus ribosomes are "recycled" and ready f2 genes
Ribosomal_L27e, Ribosomal L27e protein family. The N-terminal region of the eukaryotic ribosomal L27 has the KOW motif. C-terminal region is represented by this family2 genes
Ribosomal_L28e, Ribosomal L28e protein family2 genes
RNase_P_Rpp14, Rpp14 family. tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule associated with at least eight protein subunits, hPop1, Rpp14, Rpp20, Rpp25, Rpp29, Rpp30, Rpp38, and Rpp402 genes
Ribosomal_L14e, Ribosomal protein L14. This family includes the eukaryotic ribosomal protein L142 genes
Rifin_STEVOR, Rifin/stevor family. Several multicopy gene families have been described in Plasmodium falciparum, including the stevor family of subtelomeric open reading frames and the rif interspersed repetitive elements. Both families contai2 genes
Rib_hydrolayse, ADP-ribosyl cyclase. ADP-ribosyl cyclase EC:3.2.2.5 (also know as cyclic ADP-ribose hydrolase or CD38) synthesises cyclic-ADP ribose, a second messenger for glucose-induced insulin secretion2 genes
RAG2, Recombination activating protein 2. V-D-J recombination is the combinatorial process by which the huge range of immunoglobulin and T cell binding specificity is generated from a limited amount of genetic material. This process is synergi2 genes
Rabaptin, Rabaptin2 genes
Rad4, DNA repair protein Rad42 genes
RNA_pol_Rpb7_N, RNA polymerase Rpb7, N-terminal domain. Rpb7 bind to Rpb4 to form a heterodimer. This complex is thought to interact with the nascent RNA strand during Pol II elongation2 genes
Ribosomal_L2_C, Ribosomal Proteins L2, C-terminal domain2 genes
RLI, Possible metal-binding domain in RNase L inhibitor, RLI. Possible metal-binding domain in endoribonuclease RNase L inhibitor. Found at the N-terminal end of RNase L inhibitor proteins, adjacent to the 4Fe-4S binding domain, fer4, pfam00032 genes
Rad9, Rad9. Rad9 is required for transient cell-cycle arrests and transcriptional induction of DNA repair in response to DNA damage2 genes
RNA_pol_Rpb2_4, RNA polymerase Rpb2, domain 4. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera2 genes
Rad21_Rec8, Conserved region of Rad21 / Rec8 like protein. This family represents a conserved region found in eukaryotic cohesins of the Rad21, Rec8 and Scc1 families. Members of this family mediate sister chromatid cohesion during mitosis and2 genes
Rad21_Rec8_N, N terminus of Rad21 / Rec8 like protein. This family represents a conserved N-terminal region found in eukaryotic cohesins of the Rad21, Rec8 and Scc1 families. Members of this family mediate sister chromatid cohesion during mito2 genes
RNA_pol_Rpa43, RNA polymerase Rpa43 subunit. Subunit specific to RNA Pol I which comprises of 14 different subunits. The Rpa43 is at least one of the subunits contacted by the transcription factor TIF-IA2 genes
RTC_insert, RNA 3'-terminal phosphate cyclase (RTC), insert domain. RNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cy2 genes
Rubella_Capsid, Rubella capsid protein. Rubella virus is an enveloped positive-strand RNA virus of the family Togaviridae. Virions are composed of three structural proteins: a capsid and two membrane-spanning glycoproteins, E2 and E1. During v2 genes
Radial_spoke_3, Radial spoke protein 3. This family consists of several radial spoke protein 3 (RSP3) sequences. Eukaryotic cilia and flagella present in diverse types of cells perform motile, sensory, and developmental functions in organisms 2 genes
RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus2 genes
RGM_C, Repulsive guidance molecule (RGM) C-terminus. This family consists of several mammalian and one bird sequence from Gallus gallus (Chicken). This family represents the C-terminal region of several sequences but in others it represents th2 genes
RAMP4, Ribosome associated membrane protein RAMP4. This family consists of several ribosome associated membrane protein RAMP4 (or SERP1) sequences. Stabilisation of membrane proteins in response to stress involves the concerted action of a res2 genes
Resistin, Resistin. This family consists of several mammalian resistin proteins. Resistin is a 12.5-kDa cysteine-rich secreted polypeptide first reported from rodent adipocytes. It belongs to a multigene family termed RELMs or FIZZ proteins. P2 genes
regulation of mitotic recombination, TAS2 genes
regulation of cell cycle, IDA2 genes
regulation of neurotransmitter levels, NR2 genes
regulation of action potential, IDA2 genes
response to hypoxia, NAS2 genes
regulation of chromatin assembly/disassembly, IDA2 genes
ruffles, ISS2 genes
regulation of cytokine production, NAS2 genes
RNA polymerase II transcription factor activity, enhancer binding, NAS2 genes
ribonuclease III activity, IEA2 genes
ribonuclease P activity, IEA2 genes
RAB-protein geranylgeranyltransferase activity, TAS2 genes
retinol dehydrogenase activity, IDA2 genes
retinol dehydrogenase activity, ISS2 genes
ribonucleoside-diphosphate reductase activity, NAS2 genes
receptor signaling protein serine/threonine kinase signaling protein activity, NR2 genes
Rab escort protein activity, IEA2 genes
Ras GTPase activator activity, IEA2 genes
receptor binding, ISS2 genes
ribosome, NR2 genes
regulation of glycolysis, TAS2 genes
regulation of DNA replication, ISS2 genes
regulation of DNA replication, NAS2 genes
regulation of DNA repair, TAS2 genes
regulation of transcription from Pol II promoter, ISS2 genes
RNA-nucleus export, IEA2 genes
regulation of protein biosynthesis, NAS2 genes
regulation of translation, ISS2 genes
regulation of cell volume, NAS2 genes
regulation of muscle contraction, NAS2 genes
regulation of striated muscle contraction, NR2 genes
response to stress, IC2 genes
response to stress, IEP2 genes
response to stress, ISS2 genes
response to oxidative stress, IDA2 genes
response to oxidative stress, NAS2 genes
response to unfolded protein, IEA2 genes
regulation of epidermal growth factor receptor activity, TAS2 genes
RAS protein signal transduction, NR2 genes
regulation of actin polymerization and/or depolymerization, TAS2 genes
RNA methyltransferase activity, IEA2 genes
regulation of G-protein coupled receptor protein signaling pathway, IEA2 genes
regulation of G-protein coupled receptor protein signaling pathway, ISS2 genes
regulation of cell shape, NAS2 genes
RAN protein binding, NAS2 genes
release of cytoplasmic sequestered NF-kappaB, IDA2 genes
ribonucleoside monophosphate biosynthesis, IEA2 genes
response to heat, TAS2 genes
response to cold, ISS2 genes
response to UV, IDA2 genes
response to UV, TAS2 genes
response to external stimulus, IEP2 genes
response to external stimulus, NAS2 genes
response to external stimulus, TAS2 genes
response to virus, IEP2 genes
response to virus, ISS2 genes
response to bacteria, TAS2 genes
response to hormone stimulus, IDA2 genes
response to hormone stimulus, TAS2 genes
regulation of signal transduction, ISS2 genes
response to organic substance, NAS2 genes
regulation of proton transport, NAS2 genes
racemase and epimerase activity, acting on amino acids and derivatives, IEA2 genes
Rap guanyl-nucleotide exchange factor activity, IDA2 genes
Rho GTPase binding, ISS2 genes
regulation of lipid metabolism, NAS2 genes
regulation of vasoconstriction, TAS2 genes
regulation of endocytosis, TAS2 genes
regulation of Wnt receptor signaling pathway, ISS2 genes
regulation of cell adhesion, IDA2 genes
regulation of cell adhesion, ISS2 genes
regulation of blood coagulation, TAS2 genes
regulation of bone mineralization, IEA2 genes
regulation of cell redox homeostasis, TAS2 genes
ribonucleoprotein complex, NAS2 genes
Rac guanyl-nucleotide exchange factor activity, IDA2 genes
regulation of growth, ISS2 genes
regulation of cytokine biosynthesis, ISS2 genes
retrograde transport, endosome to Golgi, NAS2 genes
regulation of vasodilation, NAS2 genes
retinol metabolism, ISS2 genes
response to starvation, ISS2 genes
regulation of apoptosis, TAS2 genes
ribosome binding, ISS2 genes
regulation of vascular permeability, TAS2 genes
regulation of viral genome replication, TAS2 genes
regulation of neuron differentiation, ISS2 genes
regulation of protein kinase activity, IDA2 genes
regulation of JNK cascade, ISS2 genes
Rap GTPase activator activity, IDA2 genes
regulation of synaptic plasticity, ISS2 genes
regulation of physiological process, IEA2 genes
regulation of cellular process, ISS2 genes
RVP, Retroviral aspartyl protease. Single domain aspartyl proteases from retroviruses, retrotransposons, and badnaviruses (plant dsDNA viruses). These proteases are generally part of a larger polyprotein; usually pol, more rarely gag. Retrovir1 genes
Ribosomal_S4, Ribosomal protein S4/S9 N-terminal domain. This family includes small ribosomal subunit S9 from prokaryotes and S16 from metazoans. This domain is predicted to bind to ribosomal RNA. This domain is composed of four helices in the1 genes
Ribosomal_S3_C, Ribosomal protein S3, C-terminal domain. This family contains a central domain pfam00013, hence the amino and carboxyl terminal domains are stored separately. This is a minimal carboxyl-terminal domain. Some are much longer1 genes
Ribosomal_S14, Ribosomal protein S14p/S29e. This family includes both ribosomal S14 from prokaryotes and S29 from eukaryotes1 genes
Ribosomal_L5, Ribosomal protein L51 genes
Ribonuc_red_lgN, Ribonucleotide reductase, all-alpha domain1 genes
Ribosomal_L36, Ribosomal protein L361 genes
Ribonuclease_T2, Ribonuclease T2 family1 genes
Ribosomal_L20, Ribosomal protein L201 genes
ROK, ROK family1 genes
Ribosomal_L12, Ribosomal protein L7/L12 C-terminal domain1 genes
Ribosomal_L21p, Ribosomal prokaryotic L21 protein1 genes
Ribosomal_S16, Ribosomal protein S161 genes
RNA_pol, DNA-dependent RNA polymerase. This is a family of single chain RNA polymerases1 genes
Ribosomal_L27, Ribosomal L27 protein1 genes
Ribosomal_L40e, Ribosomal L40e family. Bovine L40 has been identified as a secondary RNA binding protein. L40 is fused to a ubiquitin protein1 genes
Ribosomal_S19e, Ribosomal protein S19e1 genes
RNA_pol_Rpb5_C, RNA polymerase Rpb5, C-terminal domain. The assembly domain of Rpb5. The archaeal equivalent to this domain is subunit H. Subunit H lacks the N-terminal domain1 genes
RNA_pol_Rpb6, RNA polymerase Rpb6. Rpb6 is an essential subunit in the eukaryotic polymerases Pol I, II and III. The bacterial equivalent to Rpb6 is the omega subunit. Rpb6 and omega are structurally conserved and both function in polymerase a1 genes
RNA_pol_N, RNA polymerases N / 8 kDa subunit1 genes
Ribosomal_L17, Ribosomal protein L171 genes
Ribosomal_S28e, Ribosomal protein S28e1 genes
Ribosomal_L19, Ribosomal protein L191 genes
Ribosomal_L35Ae, Ribosomal protein L35Ae1 genes
Ribosomal_S6, Ribosomal protein S61 genes
Ribosomal_L9_N, Ribosomal protein L9, N-terminal domain1 genes
Ribosomal_S24e, Ribosomal protein S24e1 genes
Ribosomal_L15, Ribosomal protein L15 amino terminal region. This family is always associated with pfam00256. This family is diagnostic of ribosomal L15 proteins1 genes
RNase_HII, Ribonuclease HII1 genes
Ribosomal_L37ae, Ribosomal L37ae protein family. This ribosomal protein is found in archaebacteria and eukaryotes. It contains four conserved cysteine residues that may bind to zinc1 genes
Ribosomal_L38e, Ribosomal L38e protein family1 genes
RNase_P_p30, RNase P subunit p30. This protein is part of the RNase P complex that is involved in tRNA maturation1 genes
Rad1, Repair protein Rad1/Rec1/Rad171 genes
RNA_POL_M_15KD, RNA polymerases M/15 Kd subunit1 genes
Ribonuc_red_lgC, Ribonucleotide reductase, barrel domain1 genes
Rer1, Rer1 family. RER1 family protein are involved in involved in the retrieval of some endoplasmic reticulum membrane proteins from the early golgi compartment. The C terminus of yeast Rer1p interacts with a coatomer complex1 genes
Remorin_C, Remorin, C-terminal region. Remorin binds both simple and complex galaturonides. The N-terminal region of remorin is proline rich, while the C-terminal region has been predicted to form a coiled- coil, that is expected to interact w1 genes
Rad10, DNA repair protein rad101 genes
RNA_pol_Rpb8, RNA polymerase Rpb8. Rpb8 is a subunit common to the three yeast RNA polymerases, pol I, II and III. Rpb8 interacts with the largest subunit Rpb1, and with Rpb3 and Rpb11, two smaller subunits1 genes
RNA_pol_Rpb5_N, RNA polymerase Rpb5, N-terminal domain. Rpb5 has a bipartite structure which includes a eukaryote-specific N-terminal domain and a C-terminal domain resembling the archaeal RNAP subunit H. The N-terminal domain is involved in D1 genes
RNA_pol_Rpb4, RNA polymerase Rpb41 genes
Ribosomal_L23eN, Ribosomal protein L23, N-terminal domain. The N-terminal domain appears to be specific to the eukaryotic ribosomal proteins L25, L23, and L23a1 genes
Rpr2, RNAse P Rpr2/Rpp21 subunit domain. This family contains a ribonuclease P subunit of humans and yeast. Other members of the family include the probable archaeal homologues. This subunit possibly binds the precursor tRNA1 genes
Rep-A_N, Replication factor-A protein 1, N-terminal domain1 genes
Rcd1, Cell differentiation family, Rcd1-like. Two of the members in this family have been characterised as being involved in regulation of Ste11 regulated sex genes. Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic aci1 genes
Rad52_Rad22, Rad52/22 family double-strand break repair protein. The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This family i1 genes
RmlD_sub_bind, RmlD substrate binding domain. L-rhanmose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhanmose, is synthesised by four different enzymes the final one of which is RmlD. The RmlD substrate b1 genes
RINT1_TIP1, RINT-1 / TIP-1 family. This family includes RINT-1, a Rad50 interacting protein which participates in radiation induced checkpoint control, as well as the TIP-1 protein from yeast that seems to be involved in a complex with Sec20p 1 genes
Rft-1, Rft protein1 genes
Ribophorin_I, Ribophorin I. Ribophorin I is an essential subunit of oligosaccharyltransferase (OST), which is also known as Dolichyl-diphosphooligosaccharide--protein glycosyltransferase, (EC:2.4.1.119). OST catalyses the transfer of an oligos1 genes
Ribosomal_S30, Ribosomal protein S301 genes
RRS1, Ribosome biogenesis regulatory protein (RRS1). This family consists of several eukaryotic ribosome biogenesis regulatory (RRS1) proteins. RRS1 is a nuclear protein that is essential for the maturation of 25 S rRNA and the 60 S ribosomal 1 genes
RNA_pol_Rpb1_7, RNA polymerase Rpb1, domain 7. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera1 genes
RNA_pol_Rpb1_6, RNA polymerase Rpb1, domain 6. RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymera1 genes
RbsD_FucU, RbsD / FucU transport protein family. The Escherichia coli high-affinity ribose-transport system consists of six proteins encoded by the rbs operon (rbsD, rbsA, rbsC, rbsB, rbsK and rbsR). Of the six components, RbsD is the only one1 genes
Rib_recp_KP_reg, Ribosome receptor lysine/proline rich region. This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear1 genes
RNA_pol_Rpc4, RNA polymerase III RPC4. Specific subunit for Pol III, the tRNA specific polymerase1 genes
RNA_pol_Rpc34, RNA polymerase Rpc34 subunit. Subunit specific to RNA Pol III, the tRNA specific polymerase. The C34 subunit of yeast RNA Pol III is part of a subcomplex of three subunits which have no counterpart in the other two nuclear RNA p1 genes
RHS_repeat, RHS Repeat. RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats1 genes
RNA_pol_Rpc82, RNA polymerase III subunit RPC82. This family consists of several DNA-directed RNA polymerase III polypeptides which are related to the Saccharomyces cerevisiae RPC82 protein. RNA polymerase C (III) promotes the transcription of1 genes
Ribophorin_II, Ribophorin II (RPN2). This family consists of several eukaryotic Ribophorin II (RPN2) proteins. The mammalian oligosaccharyltransferase (OST) is a protein complex that effects the cotranslational N-glycosylation of newly synthes1 genes
RHD3, Root hair defective 3 GTP-binding protein (RHD3). This family consists of several eukaryotic root hair defective 3 like GTP-binding proteins. It has been speculated that the RHD3 protein is a member of a novel class of GTP-binding protei1 genes
Rib_5-P_isom_A, Ribose 5-phosphate isomerase A (phosphoriboisomerase A). This family consists of several ribose 5-phosphate isomerase A or phosphoriboisomerase A (EC:5.3.1.6) from bacteria, eukaryotes and archaea1 genes
REX1, REX1 DNA Repair. REX1 is required for DNA repair in yeast, and has homologues in other Eukaryotes1 genes
RNA_pol_I_A49, A49-like RNA polymerase I associated factor. Saccharomyces cerevisiae A49 is a specific subunit associated with RNA polymerase I (Pol I) in eukaryotes. Pol I maintains transcription activities in A49 deletion mutants. However, s1 genes
RNA_pol_Rpa2_4, RNA polymerase I, Rpa2 specific domain. This domain is found between domain 3 (pfam04565) and domain 5 (pfam04565), but shows no homology to domain 4 of Rpb2. The external domains in multisubunit RNA polymerase (those most dist1 genes
RecQ5, RecQ helicase protein-like 5 (RecQ5). This family represents a conserved region approximately 200 residues long within eukaryotic RecQ helicase protein-like 5 (RecQ5). The RecQ helicases have been implicated in DNA repair and recombinat1 genes
Rab5ip, Rab5-interacting protein (Rab5ip). This family consists of several Rab5-interacting protein (RIP5 or Rab5ip ) sequences. The ras-related GTPase rab5 is rate-limiting for homotypic early endosome fusion. Rab5ip represents a novel rab5 i1 genes
reproduction, IEP1 genes
regulation of DNA recombination, IEP1 genes
regulation of DNA recombination, ISS1 genes
regulation of cell cycle, IEP1 genes
regulation of cyclin dependent protein kinase activity, ISS1 genes
recombinase activity, NAS1 genes
ribonuclease MRP activity, IDA1 genes
ribonuclease MRP complex, IDA1 genes
ribonuclease MRP complex, TAS1 genes
ribosomal DNA (rDNA) binding, NAS1 genes
response to reactive oxygen species, ISS1 genes
response to reactive oxygen species, NAS1 genes
response to superoxide, ISS1 genes
response to superoxide, TAS1 genes
response to oxygen radicals, TAS1 genes
RNA cap binding, NAS1 genes
response to acid, TAS1 genes
regulation of action potential, TAS1 genes
RNA methylation, NAS1 genes
retinoid metabolism, IDA1 genes
regulation of cell growth, IDA1 genes
regulation of cell growth, IEP1 genes
regulation of cell growth, TAS1 genes
ruffles, NAS1 genes
retinal dehydrogenase activity, IDA1 genes
RNA polymerase II transcription factor activity, IDA1 genes
RNA polymerase II transcription factor activity, ISS1 genes
RNA polymerase II transcription factor activity, NAS1 genes
RNA polymerase II transcription factor activity, enhancer binding, NR1 genes
retinoic acid receptor activity, IDA1 genes
RNA polymerase III transcription factor activity, NR1 genes
RNA binding, IPI1 genes
RNA helicase activity, NAS1 genes
RNA-3'-phosphate cyclase activity, NAS1 genes
RNA-3'-phosphate cyclase activity, TAS1 genes
RNA-directed DNA polymerase activity, IEA1 genes
RNA-directed DNA polymerase activity, NAS1 genes
renin activity, TAS1 genes
ribonuclease H activity, TAS1 genes
ribonuclease III activity, IDA1 genes
ribonuclease P activity, IDA1 genes
ribonuclease activity, IDA1 genes
ribonuclease activity, ISS1 genes
RAB-protein geranylgeranyltransferase activity, IEA1 genes
receptor signaling protein serine/threonine kinase activity, NAS1 genes
receptor signaling protein serine/threonine kinase activity, NR1 genes
receptor signaling protein serine/threonine kinase activity, TAS1 genes
ribosomal protein S6 kinase activity, NAS1 genes
ribokinase activity, IEA1 genes
ribonucleoside-diphosphate reductase activity, IEA1 genes
ribose-phosphate diphosphokinase activity, NAS1 genes
ribose-phosphate diphosphokinase activity, TAS1 genes
ribulose-phosphate 3-epimerase activity, IEA1 genes
ribose-5-phosphate isomerase activity, NAS1 genes
receptor activity, IC1 genes
receptor activity, IPI1 genes
receptor activity, ISS1 genes
receptor signaling protein activity, ISS1 genes
Ran guanyl-nucleotide exchange factor activity, IDA1 genes
Ran guanyl-nucleotide exchange factor activity, ISS1 genes
Ran guanyl-nucleotide exchange factor activity, NAS1 genes
Ran guanyl-nucleotide exchange factor activity, TAS1 genes
Ras guanyl-nucleotide exchange factor activity, IDA1 genes
Ras guanyl-nucleotide exchange factor activity, IEP1 genes
Ras guanyl-nucleotide exchange factor activity, NAS1 genes
Ras guanyl-nucleotide exchange factor activity, NR1 genes
Rho guanyl-nucleotide exchange factor activity, IDA1 genes
Rho guanyl-nucleotide exchange factor activity, ISS1 genes
Rho guanyl-nucleotide exchange factor activity, NR1 genes
RAB GDP-dissociation inhibitor activity, IEA1 genes
RAB GDP-dissociation inhibitor activity, TAS1 genes
Ran GTPase activator activity, TAS1 genes
Ras GTPase activator activity, NR1 genes
Rho GTPase activator activity, IMP1 genes
receptor binding, IDA1 genes
retinoid binding, ISS1 genes
respiratory chain complex III (sensu Eukarya), TAS1 genes
respiratory chain complex IV (sensu Eukarya), IC1 genes
rough endoplasmic reticulum, IDA1 genes
rough endoplasmic reticulum, TAS1 genes
Rab-protein geranylgeranyltransferase complex, IEA1 genes
Rab-protein geranylgeranyltransferase complex, TAS1 genes
ribonucleoside-diphosphate reductase complex, NAS1 genes
regulation of DNA replication, IEA1 genes
regulation of DNA replication, TAS1 genes
RNA-dependent DNA replication, IEA1 genes
RNA-dependent DNA replication, NAS1 genes
regulation of DNA repair, NAS1 genes
RNA elongation, IDA1 genes
RNA elongation, NAS1 genes
regulation of transcription, DNA-dependent, IC1 genes
regulation of transcription from Pol II promoter, IDA1 genes
regulation of transcription from Pol II promoter, IMP1 genes
regulation of transcription from Pol II promoter, NAS1 genes
regulation of global transcription from Pol II promoter, NAS1 genes
rRNA processing, IDA1 genes
rRNA processing, ISS1 genes
RNA elongation from Pol II promoter, IDA1 genes
RNA transcription termination from mitochondrial promoter, TAS1 genes
RNA processing, ISS1 genes
RNA processing, NAS1 genes
RNA processing, NR1 genes
RNA catabolism, NAS1 genes
RNA catabolism, NR1 genes
RNA-nucleus export, NAS1 genes
regulation of protein biosynthesis, ISS1 genes
regulation of translation, NR1 genes
regulation of translational initiation, IDA1 genes
regulation of translational termination, NAS1 genes
ribosomal protein-nucleus import, NAS1 genes
regulation of cell volume, IEA1 genes
regulation of cell volume, ISS1 genes
regulation of pH, IDA1 genes
regulation of pH, ISS1 genes
regulation of pH, NAS1 genes
regulation of pH, TAS1 genes
retrograde transport, Golgi to ER, IDA1 genes
retrograde transport, Golgi to ER, ISS1 genes
retrograde transport, Golgi to ER, TAS1 genes
receptor mediated endocytosis, IDA1 genes
receptor mediated endocytosis, IEA1 genes
regulation of smooth muscle contraction, ISS1 genes
regulation of smooth muscle contraction, NAS1 genes
regulation of smooth muscle contraction, NR1 genes
regulation of striated muscle contraction, NAS1 genes
response to DNA damage stimulus, ISS1 genes
response to DNA damage stimulus, NAS1 genes
response to oxidative stress, ISS1 genes
redox signal response, TAS1 genes
response to lipid hydroperoxide, NR1 genes
response to unfolded protein, IDA1 genes
response to unfolded protein, IEP1 genes
ribosome biogenesis, ISS1 genes
ribosome biogenesis, NAS1 genes
regulation of mitosis, IDA1 genes
regulation of mitosis, NAS1 genes
regulation of S phase of mitotic cell cycle, IMP1 genes
regulation of exit from mitosis, IMP1 genes
regulation of exit from mitosis, TAS1 genes
receptor guanylyl cyclase signaling pathway, NAS1 genes
RAS protein signal transduction, IDA1 genes
RAS protein signal transduction, ISS1 genes
Rho protein signal transduction, IDA1 genes
Rho protein signal transduction, NAS1 genes
regulation of rhodopsin gene activity, TAS1 genes
response to nutrients, NR1 genes
respiratory gaseous exchange, NAS1 genes
respiratory gaseous exchange, NR1 genes
regulation of actin polymerization and/or depolymerization, ISS1 genes
regulation of actin polymerization and/or depolymerization, NAS1 genes
RNA-dependent ATPase activity, TAS1 genes
regulation of blood pressure, IDA1 genes
regulation of blood pressure, ISS1 genes
regulation of G-protein coupled receptor protein signaling pathway, IDA1 genes
Ral guanyl-nucleotide exchange factor activity, NAS1 genes
regulation of cell shape, IDA1 genes
RNA splicing, IDA1 genes
RNA splicing, NR1 genes
retinoic acid 4-hydroxylase activity, TAS1 genes
ribonuclease inhibitor activity, TAS1 genes
riboflavin kinase activity, NAS1 genes
release of cytoplasmic sequestered NF-kappaB, NAS1 genes
regulation of smoothened receptor signaling pathway, ISS1 genes
regulation of smoothened receptor signaling pathway, TAS1 genes
regulation of Notch signaling pathway, IGI1 genes
ribonuclease E activity, TAS1 genes
ribonucleoside monophosphate biosynthesis, NAS1 genes
ribonucleoside monophosphate biosynthesis, TAS1 genes
response to temperature, ISS1 genes
response to temperature, NAS1 genes
response to temperature, TAS1 genes
response to pH, IDA1 genes
rRNA transcription, ISS1 genes
rRNA transcription, TAS1 genes
response to radiation, IDA1 genes
response to radiation, IEP1 genes
response to radiation, ISS1 genes
response to radiation, NAS1 genes
response to xenobiotic stimulus, IDA1 genes
response to xenobiotic stimulus, ISS1 genes
response to UV, ISS1 genes
response to light, TAS1 genes
RNA modification, TAS1 genes
rhodopsin mediated phototransduction, TAS1 genes
response to external stimulus, IDA1 genes
response to biotic stimulus, TAS1 genes
response to virus, IDA1 genes
response to virus, NR1 genes
response to bacteria, NAS1 genes
response to pathogenic bacteria, NAS1 genes
response to fungi, TAS1 genes
response to pathogenic fungi, TAS1 genes
response to abiotic stimulus, TAS1 genes
response to toxin, IEA1 genes
response to toxin, ISS1 genes
response to toxin, NAS1 genes
response to light intensity, NAS1 genes
response to photoperiod, TAS1 genes
response to hormone stimulus, NAS1 genes
response to glucose stimulus, IDA1 genes
response to glucose stimulus, NAS1 genes
response to extracellular stimulus, IDA1 genes
response to organic substance, IDA1 genes
response to organic substance, TAS1 genes
response to metal ion, IDA1 genes
response to zinc ion, IDA1 genes
RNA metabolism, ISS1 genes
RNA metabolism, NAS1 genes
RNA metabolism, TAS1 genes
rRNA metabolism, ISS1 genes
rRNA catabolism, NAS1 genes
regulation of myogenesis, NAS1 genes
RNA interference, ISS1 genes
RNA interference, NAS1 genes
regulator of G-protein signaling activity, TAS1 genes
RNA polymerase II transcription mediator activity, IEA1 genes
RNA polymerase II transcription mediator activity, TAS1 genes
RAC protein signal transduction, IGI1 genes
RAC protein signal transduction, NAS1 genes
racemase and epimerase activity, NAS1 genes
racemase and epimerase activity, acting on amino acids and derivatives, NAS1 genes
racemase and epimerase activity, acting on carbohydrates and derivatives, ISS1 genes
regulation of transforming growth factor beta receptor signaling pathway, ISS1 genes
regulation of transforming growth factor beta receptor signaling pathway, NAS1 genes
Ras interactor activity, IDA1 genes
Ras interactor activity, ISS1 genes
Ras interactor activity, TAS1 genes
Rho interactor activity, NAS1 genes
Rho interactor activity, TAS1 genes
Rho GTPase binding, IDA1 genes
Rho GTPase binding, NAS1 genes
Rab guanyl-nucleotide exchange factor activity, IDA1 genes
Rab guanyl-nucleotide exchange factor activity, NAS1 genes
Rab interactor activity, NAS1 genes
Rab interactor activity, TAS1 genes
regulation of exocytosis, TAS1 genes
regulation of vasoconstriction, NAS1 genes
removal of superoxide radicals, IDA1 genes
regulation of mitotic metaphase/anaphase transition, IDA1 genes
regulation of endocytosis, NAS1 genes
regulation of cell adhesion, TAS1 genes
regulation of proteolysis and peptidolysis, ISS1 genes
regulation of ossification, TAS1 genes
respiratory tube development, NAS1 genes
regulation of cell migration, TAS1 genes
ribosome receptor activity, NAS1 genes
RNA interference, targeting of mRNA for destruction, IEP1 genes
regulation of bone mineralization, ISS1 genes
regulation of bone mineralization, TAS1 genes
regulation of cell redox homeostasis, IDA1 genes
regulation of axon extension, NAS1 genes
regulation of axon extension, TAS1 genes
ribonucleoprotein complex, ISS1 genes
receptor activator activity, IDA1 genes
rRNA N-glycosylase activity, IEA1 genes
Rac guanyl-nucleotide exchange factor activity, ISS1 genes
regulation of cAMP biosynthesis, IDA1 genes
regulation of actin filament length, NAS1 genes
regulation of actin filament length, TAS1 genes
regulation of Rho protein signal transduction, ISS1 genes
regulation of Rho protein signal transduction, NAS1 genes
regulation of body size, ISS1 genes
regulation of gene expression, epigenetic, ISS1 genes
regulation of cytokine biosynthesis, TAS1 genes
regulation of cell proliferation, IEP1 genes
regulation of T-cell proliferation, ISS1 genes
retrograde transport, endosome to Golgi, ISS1 genes
regulation of protein catabolism, IDA1 genes
regulation of protein catabolism, IEA1 genes
regulation of protein catabolism, NAS1 genes
response to chemical substance, IEP1 genes
ribosome assembly, NAS1 genes
regulation of eye photoreceptor cell development, ISS1 genes
response to drug, IDA1 genes
response to drug, NAS1 genes
response to hydrogen peroxide, IDA1 genes
retinol metabolism, IDA1 genes
retinol metabolism, NAS1 genes
retinoic acid metabolism, IDA1 genes
retinoic acid metabolism, NAS1 genes
retinal metabolism, IDA1 genes
retinal metabolism, NAS1 genes
regulation of circadian rhythm, NAS1 genes
retinoic acid receptor binding, IPI1 genes
regulation of apoptosis, IDA1 genes
regulation of apoptosis, IMP1 genes
regulation of amyloid precursor protein biosynthesis, IDA1 genes
regulation of fusion of sperm to egg plasma membrane, NAS1 genes
regulation of GTPase activity, NAS1 genes
regulation of vascular permeability, NAS1 genes
regulated secretory pathway, IDA1 genes
regulated secretory pathway, NAS1 genes
regulation of innate immune response, NAS1 genes
retroviral genome replication, NAS1 genes
regulation of retroviral genome replication, IDA1 genes
regulation of bone resorption, NAS1 genes
regulation of circadian sleep/wake cycle, sleep, ISS1 genes
regulation of isotype switching, NAS1 genes
regulation of isotype switching, TAS1 genes
regulation of MHC class I biosynthesis, NAS1 genes
regulation of interleukin-18 biosynthesis, NAS1 genes
regulation of transcription, IDA1 genes
regulation of transcription, TAS1 genes
response to ethanol, ISS1 genes
regulation of cholesterol biosynthesis, NAS1 genes
regulation of B-cell differentiation, ISS1 genes
regulation of T-cell differentiation, NAS1 genes
regulation of cell differentiation, IEP1 genes
regulation of hemocyte differentiation, ISS1 genes
regulation of T-helper cell differentiation, ISS1 genes
regulation of T-helper cell differentiation, NAS1 genes
regulation of T-helper 1 cell differentiation, IDA1 genes
regulation of myeloid blood cell differentiation, TAS1 genes
regulation of osteoclast differentiation, NAS1 genes
regulation of protein kinase activity, TAS1 genes
regulation of transcriptional preinitiation complex formation, IDA1 genes
regulation of JNK cascade, IDA1 genes
regulation of RAS protein signal transduction, IDA1 genes
Rap GTPase activator activity, NAS1 genes
regulation of virion penetration, IDA1 genes
response to arsenate, IEA1 genes
response to arsenate, NAS1 genes
reduction of virulence, NAS1 genes
regulation of hormone biosynthesis, NAS1 genes
regulation of mitochondrial membrane permeability, TAS1 genes
regulation of neurotransmitter secretion, TAS1 genes
retinoid X receptor binding, IPI1 genes
retinoid X receptor binding, TAS1 genes
receptor antagonist activity, NAS1 genes
receptor antagonist activity, TAS1 genes
regulation of synaptic plasticity, NAS1 genes
regulation of neuronal synaptic plasticity, NAS1 genes
regulation of neuronal synaptic plasticity, TAS1 genes
regulation of long-term neuronal synaptic plasticity, ISS1 genes
Rac GTPase binding, IDA1 genes
Rac GTPase binding, ISS1 genes
rhodopsin kinase activity, IEA1 genes
RNA transport, IDA1 genes
RNA transport, IEA1 genes
RNA transport, ISS1 genes
regulation of homocysteine metabolism, ISS1 genes
regulation of mRNA processing, IDA1 genes
regulation of protein secretion, IDA1 genes
regulation of protein secretion, NAS1 genes
regulation of inflammatory response, IMP1 genes
regulation of inflammatory response, NAS1 genes
regulation of inflammatory response, TAS1 genes
regulation of peptidyl-tyrosine phosphorylation, IDA1 genes
RS domain binding, NAS1 genes
regulation of dendrite morphogenesis, NAS1 genes
regulation of immune response, NAS1 genes
response to freezing, IEA1 genes
regulation of T-cell activation, IDA1 genes
AS3D: Alternative Splicing Structural Genomics Projects
CARB/UMBI