| protein binding, IEA | 563 genes |
| Pkinase, Protein kinase domain | 494 genes |
| protein amino acid phosphorylation, IEA | 325 genes |
| proteolysis and peptidolysis, IEA | 291 genes |
| protein ubiquitination, IEA | 257 genes |
| protein serine/threonine kinase activity, IEA | 225 genes |
| PH, PH domain. PH stands for pleckstrin homology | 215 genes |
| protein binding, IPI | 209 genes |
| Podocalyxin, Podocalyxin. This family consists of several eukaryotic podocalyxin proteins. Podocalyxin is a major membrane protein of the glomerular epithelium and is thought to be involved in maintenance of the architecture of the foot proces | 168 genes |
| plasma membrane, TAS | 168 genes |
| protein binding, TAS | 165 genes |
| protein transport, IEA | 156 genes |
| protein biosynthesis, IEA | 143 genes |
| PDZ, PDZ domain (Also known as DHR or GLGF). PDZ domains are found in diverse signaling proteins | 134 genes |
| protein amino acid phosphorylation, TAS | 118 genes |
| protein-tyrosine kinase activity, IEA | 107 genes |
| positive regulation of cell proliferation, TAS | 91 genes |
| potassium ion transport, IEA | 88 genes |
| phosphate transport, IEA | 78 genes |
| proteolysis and peptidolysis, TAS | 77 genes |
| Prox1, Homeobox prospero-like protein (PROX1). The homeobox gene Prox1 is expressed in a subpopulation of endothelial cells that, after budding from veins, gives rise to the mammalian lymphatic system. Prox1 has been found to be an early speci | 76 genes |
| PHD, PHD-finger. PHD folds into an interleaved type of Zn-finger chelating 2 Zn ions in a similar manner to that of the RING and FYVE domains | 71 genes |
| protein folding, IEA | 67 genes |
| protein amino acid dephosphorylation, IEA | 66 genes |
| protein biosynthesis, TAS | 65 genes |
| protein complex assembly, TAS | 64 genes |
| peptidase activity, IEA | 64 genes |
| p450, Cytochrome P450. Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Structure is mostly alpha, and binds a heme | 61 genes |
| protein binding, NAS | 61 genes |
| protein transporter activity, IEA | 60 genes |
| protein serine/threonine kinase activity, TAS | 58 genes |
| protein binding, ISS | 53 genes |
| perception of smell, IEA | 53 genes |
| Pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase | 52 genes |
| potassium ion transport, TAS | 51 genes |
| perception of sound, IEA | 51 genes |
| PX, PX domain. PX domains bind to phosphoinositides | 48 genes |
| protein amino acid dephosphorylation, TAS | 46 genes |
| positive regulation of I-kappaB kinase/NF-kappaB cascade, IMP | 46 genes |
| protein kinase activity, IEA | 45 genes |
| postsynaptic membrane, IEA | 42 genes |
| PMP22_Claudin, PMP-22/EMP/MP20/Claudin family | 41 genes |
| protein modification, TAS | 41 genes |
| Poxvirus_B22R, Poxvirus B22R protein | 40 genes |
| Pep_M12B_propep, Reprolysin family propeptide. This region is the propeptide for members of peptidase family M12B. The propeptide contains a sequence motif similar to the "cysteine switch" of the matrixins. This motif is found at the C terminu | 38 genes |
| PspA_IM30, PspA/IM30 family. This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exp | 38 genes |
| protein folding, TAS | 37 genes |
| protein amino acid phosphorylation, NAS | 37 genes |
| pre-mRNA splicing factor activity, TAS | 37 genes |
| Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding do | 36 genes |
| potassium channel activity, IEA | 36 genes |
| protein amino acid glycosylation, IEA | 33 genes |
| Pkinase_C, Protein kinase C terminal domain | 32 genes |
| proton transport, IEA | 32 genes |
| protein tyrosine phosphatase activity, IEA | 31 genes |
| plasma membrane, NR | 31 genes |
| pregnancy, TAS | 31 genes |
| PID, Phosphotyrosine interaction domain (PTB/PID) | 30 genes |
| Pneumo_att_G, Pneumovirinae attachment membrane glycoprotein G | 30 genes |
| proton-transporting two-sector ATPase complex, IEA | 30 genes |
| peptidyl-prolyl cis-trans isomerase activity, IEA | 29 genes |
| peroxisome, TAS | 29 genes |
| proteolysis and peptidolysis, NAS | 29 genes |
| perception of sound, TAS | 29 genes |
| positive regulation of I-kappaB kinase/NF-kappaB cascade, IEP | 29 genes |
| Paf1, Paf1. Members of this family are components of the RNA polymerase II associated Paf1 complex. The Paf1 complex functions during the elongation phase of transcription in conjunction with Spt4-Spt5 and Spt16-Pob3i | 28 genes |
| Peptidase_M10, Matrixin. The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis | 25 genes |
| protein-tyrosine kinase activity, TAS | 25 genes |
| purinergic nucleotide receptor activity, G-protein coupled, IEA | 25 genes |
| protein amino acid phosphorylation, IDA | 24 genes |
| PLAT, PLAT/LH2 domain. This domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic | 23 genes |
| peroxidase activity, IEA | 22 genes |
| protein serine/threonine kinase activity, IDA | 22 genes |
| protein biosynthesis, NAS | 22 genes |
| protein amino acid glycosylation, TAS | 22 genes |
| PDEase_I, 3'5'-cyclic nucleotide phosphodiesterase | 21 genes |
| Peptidase_M10_N, Matrix metalloprotease, N-terminal domain. This family is found N-terminal to the catalytic domain of matrixin | 21 genes |
| protein kinase cascade, IDA | 21 genes |
| PI3_PI4_kinase, Phosphatidylinositol 3- and 4-kinase | 20 genes |
| PWWP, PWWP domain. The PWWP domain is named after a conserved Pro-Trp-Trp-Pro motif. The function of the domain is currently unknown | 20 genes |
| protein tyrosine phosphatase activity, TAS | 20 genes |
| protein tyrosine/serine/threonine phosphatase activity, IEA | 20 genes |
| phospholipid biosynthesis, IEA | 20 genes |
| Proteasome, Proteasome A-type and B-type | 19 genes |
| PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences | 19 genes |
| phosphoprotein phosphatase activity, IEA | 19 genes |
| phosphate metabolism, TAS | 19 genes |
| PI-PLC-X, Phosphatidylinositol-specific phospholipase C, X domain. This associates with pfam00387 to form a single structural unit | 18 genes |
| PP2C, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase | 18 genes |
| PAS, PAS domain. CAUTION. This family does not currently match all known examples of PAS domains. PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channel | 18 genes |
| PSI, Plexin repeat. A cysteine rich repeat found in several different extracellular receptors. The function of the repeat is unknown. Three copies of the repeat are found Plexin. Two copies of the repeat are found in mahogany protein. A relate | 18 genes |
| PAP2, PAP2 superfamily. This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2 | 18 genes |
| PA, PA domain. The PA (Protease associated) domain is found as an insert domain in diverse proteases. The PA domain is also found in a plant vacuolar sorting receptor and members of the RZF family | 18 genes |
| protein serine/threonine kinase activity, NAS | 18 genes |
| protein modification, IEA | 18 genes |
| perception of smell, NAS | 18 genes |
| perception of taste, IEA | 18 genes |
| PAAD_DAPIN, PAAD/DAPIN/Pyrin domain. This domain is predicted to contain 6 alpha helices and to have the same fold as the pfam00531 domain. This similarity may mean that this is a protein-protein interaction domain | 17 genes |
| PCI, PCI domain. This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15) | 16 genes |
| Peptidase_M1, Peptidase family M1. Members of this family are aminopeptidases. The members differ widely in specificity, hydrolysing acidic, basic or neutral N-terminal residues. This family includes leukotriene-A4 hydrolase, this enzyme also | 16 genes |
| proteasome core complex (sensu Eukarya), IEA | 16 genes |
| protein heterodimerization activity, IPI | 16 genes |
| Pou, Pou domain - N-terminal to homeobox domain | 15 genes |
| PI-PLC-Y, Phosphatidylinositol-specific phospholipase C, Y domain. This associates with pfam00388 to form a single structural unit | 15 genes |
| PB1, PB1 domain | 15 genes |
| Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These | 15 genes |
| PV-1, PV-1 protein (PLVAP). This family consists of several PV-1 (PLVAP) proteins which seem to be specific to mammals. PV-1 is a novel protein component of the endothelial fenestral and stomatal diaphragms. The function of this family is unkn | 15 genes |
| protein C-terminus binding, TAS | 15 genes |
| Peptidase_C1, Papain family cysteine protease | 14 genes |
| PGAM, Phosphoglycerate mutase family | 14 genes |
| Peptidase_C14, Caspase domain | 14 genes |
| PAC, PAC motif. PAC motif occurs C-terminal to a subset of all known PAS motifs. It is proposed to contribute to the PAS domain fold | 14 genes |
| Peptidase_M28, Peptidase family M28 | 14 genes |
| peroxisome, IEA | 14 genes |
| plasma membrane, IDA | 14 genes |
| protein biosynthesis, NR | 14 genes |
| protein kinase cascade, TAS | 14 genes |
| protein translocase activity, IEA | 14 genes |
| Peptidase_C2, Calpain family cysteine protease | 13 genes |
| phosphoinositide phospholipase C activity, TAS | 13 genes |
| plasma membrane, NAS | 13 genes |
| proteolysis and peptidolysis, NR | 13 genes |
| protein kinase C activation, IEA | 13 genes |
| proton transport, TAS | 13 genes |
| protein metabolism, IEA | 13 genes |
| Phospholip_A2_1, Phospholipase A2. Phospholipase A2 releases fatty acids from the second carbon group of glycerol. Perhaps the best known members are secreted snake venoms, but also found in secreted pancreatic and membrane-associated forms. S | 12 genes |
| Patched, Patched family. The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals | 12 genes |
| protein-nucleus import, docking, IEA | 12 genes |
| phospholipase C activation, TAS | 12 genes |
| physiological process, IEA | 12 genes |
| protein-mitochondrial targeting, TAS | 11 genes |
| protein ubiquitination, NAS | 11 genes |
| Peptidase_S8, Subtilase family. Subtilases are a family of serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like that found in the trypsin serine proteases (see pfam00089). Structure | 10 genes |
| Pribosyltran, Phosphoribosyl transferase domain. This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyltransferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyltransf | 10 genes |
| Pyridoxal_deC, Pyridoxal-dependent decarboxylase conserved domain | 10 genes |
| Pentaxin, Pentaxin family. Pentaxins are also known as pentraxins | 10 genes |
| PBD, P21-Rho-binding domain. Small domains that bind Cdc42p- and/or Rho-like small GTPases. Also known as the Cdc42/Rac interactive binding (CRIB) | 10 genes |
| PLRV_ORF5, Potato leaf roll virus readthrough protein. This family consists mainly of the potato leaf roll virus readthrough protein. This is generated via a readthrough of open reading frame 3 a coat protein allowing transcription of open rea | 10 genes |
| Patatin, Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the | 10 genes |
| pancreatic ribonuclease activity, IEA | 10 genes |
| phosphoinositide 3-kinase complex, IEA | 10 genes |
| purine nucleotide biosynthesis, IEA | 10 genes |
| protein complex assembly, IEA | 10 genes |
| protein targeting, IEA | 10 genes |
| protein serine/threonine phosphatase complex, IEA | 10 genes |
| potassium channel regulator activity, TAS | 10 genes |
| positive regulation of I-kappaB kinase/NF-kappaB cascade, ISS | 10 genes |
| protein dimerization activity, IEA | 10 genes |
| PAX, 'Paired box' domain | 9 genes |
| Peptidase_S9, Prolyl oligopeptidase family | 9 genes |
| PI3Ka, Phosphoinositide 3-kinase family, accessory domain (PIK domain). PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation | 9 genes |
| PIP5K, Phosphatidylinositol-4-phosphate 5-Kinase. This family contains a region from the common kinase core found in the type I phosphatidylinositol-4-phosphate 5-kinase (PIP5K) family as described in. The family consists of various type I, II | 9 genes |
| Polysacc_synt_2, Polysaccharide biosynthesis protein. This is a family of diverse bacterial polysaccharide biosynthesis proteins including the CapD protein, WalL protein, mannosyl-transferase, and several putative epimerases (e.g. WbiI) | 9 genes |
| phospholipid-translocating ATPase activity, IEA | 9 genes |
| phosphoinositide phospholipase C activity, IEA | 9 genes |
| proton-transporting ATP synthase complex (sensu Eukarya), TAS | 9 genes |
| protein folding, NAS | 9 genes |
| protein complex assembly, NAS | 9 genes |
| protein complex assembly, NR | 9 genes |
| protein modification, NR | 9 genes |
| protein amino acid phosphorylation, ISS | 9 genes |
| phospholipid metabolism, TAS | 9 genes |
| peripheral nervous system development, TAS | 9 genes |
| pre-mRNA splicing factor activity, IEA | 9 genes |
| protein phosphatase type 2A regulator activity, TAS | 9 genes |
| protein secretion, IEA | 9 genes |
| phosphotransferase activity, alcohol group as acceptor, IEA | 9 genes |
| platelet activation, NAS | 9 genes |
| protein homodimerization activity, NAS | 9 genes |
| PDGF, Platelet-derived growth factor (PDGF) | 8 genes |
| Peptidase_M24, metallopeptidase family M24 | 8 genes |
| PARP, Poly(ADP-ribose) polymerase catalytic domain. Poly(ADP-ribose) polymerase catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for | 8 genes |
| Peptidase_S21, Assemblin (Peptidase family S21) | 8 genes |
| PI3K_C2, Phosphoinositide 3-kinase C2. Phosphoinositide 3-kinase region postulated to contain a C2 domain. Outlier of pfam00168 family | 8 genes |
| P_proprotein, Proprotein convertase P-domain. A unique feature of the eukaryotic subtilisin-like proprotein convertases is the presence of an additional highly conserved sequence of approximately 150 residues (P domain) located immediately dow | 8 genes |
| Propep_M14, Carboxypeptidase activation peptide. Carboxypeptidases are found in abundance in pancreatic secretions. The pro-segment moiety (activation peptide) accounts for up to a quarter of the total length of the peptidase, and is responsib | 8 genes |
| proteasome complex (sensu Eukarya), TAS | 8 genes |
| pepsin A activity, IEA | 8 genes |
| protein kinase activity, TAS | 8 genes |
| protein serine/threonine kinase activity, ISS | 8 genes |
| pseudouridylate synthase activity, IEA | 8 genes |
| phospholipid binding, TAS | 8 genes |
| protein amino acid dephosphorylation, NAS | 8 genes |
| peroxisome organization and biogenesis, TAS | 8 genes |
| protein kinase C activation, TAS | 8 genes |
| phototransduction, IEA | 8 genes |
| peptide cross-linking, IEA | 8 genes |
| protein kinase binding, IPI | 8 genes |
| protein homodimerization activity, ISS | 8 genes |
| positive regulation of transcription, IEA | 8 genes |
| PAN, PAN domain. The PAN domain contains a conserved core of three disulphide bridges. In some members of the family there is an additional fourth disulphide bridge the links the N and C termini of the domain. The domain is found in diverse pr | 7 genes |
| PABP, Poly-adenylate binding protein, unique domain | 7 genes |
| Plectin, Plectin repeat. This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen | 7 genes |
| PI3K_rbd, PI3-kinase family, ras-binding domain. Certain members of the PI3K family possess Ras-binding domains in their N-termini. These regions show some similarity (although not highly significant similarity) to Ras-binding pfam00788 domain | 7 genes |
| PKD, PKD domain. This domain was first identified in the Polycystic kidney disease protein PKD1. This domain has been predicted to contain an Ig-like fold | 7 genes |
| P2X_receptor, ATP P2X receptor | 7 genes |
| P5CR, Delta 1-pyrroline-5-carboxylate reductase | 7 genes |
| PCMT, Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) | 7 genes |
| Peptidase_M13, Peptidase family M13. Mammalian enzymes are typically type-II membrane anchored enzymes which are known, or believed to activate or inactivate oligopeptide (pro)-hormones such as opioid peptides. The family also contains a bacte | 7 genes |
| Porin_3, Eukaryotic porin | 7 genes |
| Peptidase_M20, Peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are Glutamate carboxypeptidases. Peptidase family M25 contains X-His | 7 genes |
| Piwi, Piwi domain. This domain is found in the protein Piwi and its relatives. The function of this domain is unknown | 7 genes |
| PGM_PMM_I, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I | 7 genes |
| Peptidase_C48, Ulp1 protease family, C-terminal catalytic domain. This domain contains the catalytic triad Cys-His-Asn | 7 genes |
| PAP_assoc, PAP/25A associated domain | 7 genes |
| Pre-SET, Pre-SET motif. This protein motif is a zinc binding motif. It contains 9 conserved cysteines that coordinate three zinc ions. It is thought that this region plays a structural role in stabilising SET domains | 7 genes |
| PMG, PMG protein. This family consists of several mouse anagen-specific protein mKAP13 (PMG1 and PMG2). PMG1 and 2 contain characteristic repeats reminiscent of the keratin-associated proteins (KAPs). Both genes are expressed in growing hair f | 7 genes |
| Prominin, Prominin. The prominins are an emerging family of proteins that among the multispan membrane proteins display a novel topology. Mouse prominin and human prominin (mouse)-like 1 (PROML1) are predicted to contain five membrane spanning | 7 genes |
| Peptidase_M13_N, Peptidase family M13. M13 peptidases are well-studied proteases found in a wide range of organisms including mammals and bacteria. In mammals they participate in processes such as cardiovascular development, blood-pressure reg | 7 genes |
| protein phosphatase type 2A complex, IEA | 7 genes |
| protein-tyrosine kinase activity, NAS | 7 genes |
| protein phosphatase inhibitor activity, TAS | 7 genes |
| protein amino acid phosphorylation, NR | 7 genes |
| protein amino acid dephosphorylation, NR | 7 genes |
| protein-nucleus import, IEA | 7 genes |
| potassium ion transport, NAS | 7 genes |
| post-Golgi transport, TAS | 7 genes |
| peptidase activity, TAS | 7 genes |
| pre-mRNA splicing factor activity, NAS | 7 genes |
| positive regulation of cell proliferation, NR | 7 genes |
| protein carrier activity, IEA | 7 genes |
| protein secretion, TAS | 7 genes |
| protein binding, bridging, NAS | 7 genes |
| positive regulation of transcription, DNA-dependent, IDA | 7 genes |
| positive regulation of transcription, ISS | 7 genes |
| PALP, Pyridoxal-phosphate dependent enzyme. Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC | 6 genes |
| Peptidase_M16, Insulinase (Peptidase family M16) | 6 genes |
| Presenilin, Presenilin. Mutations in presenilin-1 are a major cause of early onset Alzheimer's disease. It has been found that presenilin-1 binds to beta-catenin in-vivo. This family also contains SPE proteins from C.elegans | 6 genes |
| Peptidase_M41, Peptidase family M41 | 6 genes |
| PLA2_B, Lysophospholipase catalytic domain. This family consists of Lysophospholipase / phospholipase B EC:3.1.1.5 and cytosolic phospholipase A2 EC:3.1.4 which also has a C2 domain pfam00168. Phospholipase B enzymes catalyse the release of fa | 6 genes |
| Phosducin, Phosducin | 6 genes |
| Prog_receptor, Progesterone receptor | 6 genes |
| PAZ, PAZ domain. This domain is named PAZ after the proteins Piwi Argonaut and Zwille. This domain is found in two families of proteins that are involved in post-transcriptional gene silencing. These are the Piwi family and the Dicer family, t | 6 genes |
| PAD, Protein-arginine deiminase (PAD). Members of this family are found in mammals. In the presence of calcium ions, PAD enzymes EC:3.5.3.15 catalyse the post-translational modification reaction responsible for the formation of citrulline resi | 6 genes |
| Prothymosin, Prothymosin/parathymosin family. Prothymosin alpha and parathymosin are two ubiquitous small acidic nuclear proteins that are thought to be involved in cell cycle progression, proliferation, and cell differentiation | 6 genes |
| Peptidase_M16_C, Peptidase M16 inactive domain. Peptidase M16 consists of two structurally related domains. One is the active peptidase, whereas the other is inactive. The two domains hold the substrate like a clamp | 6 genes |
| PET, PET Domain. This domain is suggested to be involved in protein-protein interactions. The family is found in conjunction with pfam00412 | 6 genes |
| protein disulfide isomerase activity, TAS | 6 genes |
| phospholipase A2 activity, IEA | 6 genes |
| protein kinase C activity, TAS | 6 genes |
| protein serine/threonine phosphatase activity, IEA | 6 genes |
| protein kinase inhibitor activity, TAS | 6 genes |
| protein kinase C binding, TAS | 6 genes |
| peroxisome, NR | 6 genes |
| proteasome regulatory particle (sensu Eukarya), TAS | 6 genes |
| plasma membrane, ISS | 6 genes |
| protein complex assembly, ISS | 6 genes |
| protein amino acid dephosphorylation, ISS | 6 genes |
| protein amino acid ADP-ribosylation, IEA | 6 genes |
| protein targeting, TAS | 6 genes |
| physiological process, TAS | 6 genes |
| phototransduction, TAS | 6 genes |
| perception of smell, TAS | 6 genes |
| protein C-terminus binding, IPI | 6 genes |
| peptidoglycan catabolism, IEA | 6 genes |
| palmitoyl-CoA hydrolase activity, IEA | 6 genes |
| phosphorylation, NAS | 6 genes |
| protein domain specific binding, IEA | 6 genes |
| protein catabolism, IEA | 6 genes |
| protein heterodimerization activity, ISS | 6 genes |
| polyprenyl_synt, Polyprenyl synthetase | 5 genes |
| Peptidase_S26, Signal peptidase I | 5 genes |
| PTR2, POT family. The POT (proton-dependent oligopeptide transport) family all appear to be proton dependent transporters | 5 genes |
| Pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases | 5 genes |
| PGM_PMM_II, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II | 5 genes |
| PBX, PBX domain. The PBX domain is a bipartite acidic domain | 5 genes |
| Peptidase_A22B, Signal peptide peptidase. The members of this family are membrane proteins. In some proteins this region is found associated with pfam02225. This family corresponds with Merops subfamily A22B, the type example of which is signa | 5 genes |
| Plasmod_Pvs28, Plasmodium ookinete surface protein Pvs28. This family consists of several ookinete surface protein (Pvs28) from several species of Plasmodium. Pvs25 and Pvs28 are expressed on the surface of ookinetes. These proteins are potent | 5 genes |
| phospholipase A2 activity, TAS | 5 genes |
| polypeptide N-acetylgalactosaminyltransferase activity, TAS | 5 genes |
| protein serine/threonine kinase activity, NR | 5 genes |
| protein-lysine 6-oxidase activity, IEA | 5 genes |
| potassium channel activity, TAS | 5 genes |
| protein binding, IDA | 5 genes |
| pyrimidine nucleotide biosynthesis, IEA | 5 genes |
| protein complex assembly, IDA | 5 genes |
| protein modification, NAS | 5 genes |
| protein amino acid ADP-ribosylation, TAS | 5 genes |
| protein amino acid glycosylation, NAS | 5 genes |
| proline biosynthesis, IEA | 5 genes |
| protein-nucleus import, TAS | 5 genes |
| protein kinase cascade, ISS | 5 genes |
| pregnancy, NAS | 5 genes |
| protein tyrosine/serine/threonine phosphatase activity, TAS | 5 genes |
| phosphatidylinositol transporter activity, TAS | 5 genes |
| protein transporter activity, NAS | 5 genes |
| purine ribonucleoside monophosphate biosynthesis, IEA | 5 genes |
| porin activity, IEA | 5 genes |
| phosphatidylinositol 3-kinase activity, IEA | 5 genes |
| proton-transporting two-sector ATPase complex, TAS | 5 genes |
| pheromone receptor activity, IEA | 5 genes |
| protein kinase binding, ISS | 5 genes |
| protein kinase A binding, TAS | 5 genes |
| Profilin, Profilin | 4 genes |
| PfkB, pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases. The family includes phosphomethylpyrimidine kinase EC:2.7.4.7. This enzyme is part of the Thiamine pyrophosphate (TPP) synthesis path | 4 genes |
| Prenyltrans, Prenyltransferase and squalene oxidase repeat | 4 genes |
| PseudoU_synth_2, RNA pseudouridylate synthase. Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes RluD, a pseudouridylate synthase that | 4 genes |
| Peptidase_C12, Ubiquitin carboxyl-terminal hydrolase, family 1 | 4 genes |
| PBP, Phosphatidylethanolamine-binding protein | 4 genes |
| PTPS, 6-pyruvoyl tetrahydropterin synthase. 6-Pyruvoyl tetrahydrobiopterin synthase catalyses the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin, the second of three enzymatic steps in the synthesis of tetrahydrobio | 4 genes |
| PXA, PXA domain. This domain is associated with PX domains pfam00787 | 4 genes |
| PA28_alpha, Proteasome activator pa28 alpha subunit. PA28 activator complex (also known as 11s regulator of 20S proteasome) is a ring shaped hexameric structure of alternating alpha and beta subunits. This family represents the alpha subunit. | 4 genes |
| PA28_beta, Proteasome activator pa28 beta subunit. PA28 activator complex (also known as 11s regulator of 20S proteasome) is a ring shaped hexameric structure of alternating alpha and beta subunits. This family represents the beta subunit. The | 4 genes |
| PMT, Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyse | 4 genes |
| Prefoldin, Prefoldin subunit. This family comprises of several prefoldin subunits. The biogenesis of the cytoskeletal proteins actin and tubulin involves interaction of nascent chains of each of the two proteins with the oligomeric protein pre | 4 genes |
| Perilipin, Perilipin family. The perilipin family includes lipid droplet-associated protein (perilipin) and adipose differentiation-related protein (adipophilin) | 4 genes |
| Peptidase_C54, Peptidase family C54 | 4 genes |
| PQ-loop, PQ loop repeat. Members of this family are all membrane bound proteins possessing a pair of repeats each spanning two transmembrane helices connected by a loop. The PQ motif found on loop 2 is critical for the localisation of cystinos | 4 genes |
| PTPLA, Protein tyrosine phosphatase-like protein, PTPLA. This family includes the mammalian protein tyrosine phosphatase-like protein, PTPLA. A significant variation of PTPLA from other protein tyrosine phosphatases is the presence of proline | 4 genes |
| PA26, PA26 p53-induced protein (sestrin). PA26 is a p53-inducible protein. Its function is unknown | 4 genes |
| PP1_inhibitor, PKC-activated protein phosphatase-1 inhibitor. Contractility of vascular smooth muscle depends on phosphorylation of myosin light chains, and is modulated by hormonal control of myosin phosphatase activity. Signaling pathways ac | 4 genes |
| PHK_AB, Phosphorylase kinase alpha/beta. This family consists of several eukaryotic phosphorylase kinase alpha and beta subunits. Phosphorylase kinase (PHK) is a regulatory enzyme in glycogen metabolism. Mutations in the gene encoding the alph | 4 genes |
| Prokineticin, Prokineticin. This family consists of several prokineticin proteins and related BM8 sequences. The suprachiasmatic nucleus (SCN) controls the circadian rhythm of physiological and behavioural processes in mammals. It has been sho | 4 genes |
| phosphopyruvate hydratase complex, IEA | 4 genes |
| protein phosphatase type 2A complex, ISS | 4 genes |
| prostaglandin biosynthesis, IEA | 4 genes |
| protein-glutamine gamma-glutamyltransferase activity, IEA | 4 genes |
| prolyl oligopeptidase activity, IEA | 4 genes |
| peroxidase activity, TAS | 4 genes |
| prenyltransferase activity, IEA | 4 genes |
| protein kinase activity, NAS | 4 genes |
| protein serine/threonine phosphatase activity, NAS | 4 genes |
| protein serine/threonine phosphatase activity, TAS | 4 genes |
| protein tyrosine phosphatase activity, NAS | 4 genes |
| pyrroline-5-carboxylate reductase activity, IEA | 4 genes |
| phospholipase inhibitor activity, TAS | 4 genes |
| prostaglandin E receptor activity, TAS | 4 genes |
| platelet activating factor receptor activity, TAS | 4 genes |
| phospholipid binding, NAS | 4 genes |
| polysome, TAS | 4 genes |
| proteoglycan metabolism, TAS | 4 genes |
| protein folding, ISS | 4 genes |
| protein complex assembly, multichaperone pathway, TAS | 4 genes |
| protein targeting, NAS | 4 genes |
| phosphate transport, TAS | 4 genes |
| phagocytosis, IEA | 4 genes |
| phagocytosis, TAS | 4 genes |
| phototransduction, NAS | 4 genes |
| phototransduction, visible light, TAS | 4 genes |
| poly(A) binding, TAS | 4 genes |
| positive transcription elongation factor activity, TAS | 4 genes |
| plasminogen activator activity, IEA | 4 genes |
| positive regulation of cell proliferation, IDA | 4 genes |
| protein transporter activity, ISS | 4 genes |
| protein transporter activity, TAS | 4 genes |
| protein-lipoylation, TAS | 4 genes |
| pathogenesis, IEA | 4 genes |
| pseudouridine synthase activity, IEA | 4 genes |
| protein phosphatase type 2C activity, TAS | 4 genes |
| peptidoglycan receptor activity, IDA | 4 genes |
| phosphatidylinositol 3-kinase activity, TAS | 4 genes |
| phosphatidylinositol N-acetylglucosaminyltransferase activity, IEA | 4 genes |
| pyridine nucleotide biosynthesis, IEA | 4 genes |
| protein homodimerization activity, IPI | 4 genes |
| positive regulation of transcription, NAS | 4 genes |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity, IEA | 4 genes |
| protein heterodimerization activity, NAS | 4 genes |
| perception of taste, TAS | 4 genes |
| PK, Pyruvate kinase, barrel domain. This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains | 3 genes |
| Protamine_P1, Protamine P1 | 3 genes |
| Phosphorylase, Carbohydrate phosphorylase. The members of this family catalyse the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch, glucan or maltodextrin | 3 genes |
| PFK, Phosphofructokinase | 3 genes |
| Peptidase_S10, Serine carboxypeptidase | 3 genes |
| PRK, Phosphoribulokinase / Uridine kinase family | 3 genes |
| PLDc, Phospholipase D. Active site motif. Phosphatidylcholine-hydrolysing phospholipase D (PLD) isoforms are activated by ADP-ribosylation factors (ARFs). PLD produces phosphatidic acid from phosphatidylcholine, which may be essential for the | 3 genes |
| POLO_box, POLO box duplicated region | 3 genes |
| P53, P53 | 3 genes |
| Peptidase_M17, Cytosol aminopeptidase family, catalytic domain. The two associated zinc ions and the active site are entirely enclosed within the C-terminal catalytic domain in leucine aminopeptidase | 3 genes |
| PPTA, Protein prenyltransferase alpha subunit repeat | 3 genes |
| PseudoU_synth_1, tRNA pseudouridine synthase. Involved in the formation of pseudouridine at the anticodon stem and loop of transfer-RNAs Pseudouridine is an isomer of uridine (5-(beta-D-ribofuranosyl) uracil, and id the most abundant modified | 3 genes |
| Peptidase_M3, Peptidase family M3. This is the Thimet oligopeptidase family, large family of mammalian and bacterial oligopeptidases that cleave medium sized peptides. The group also contains mitochondrial intermediate peptidase which is encod | 3 genes |
| PWI, PWI domain | 3 genes |
| Pro_dh, Proline dehydrogenase | 3 genes |
| pKID, pKID domain. CBP and P300 bind to the pKID (phosphorylated kinase-inducible-domain) domain of CREB | 3 genes |
| PI3K_p85B, PI3-kinase family, p85-binding domain | 3 genes |
| PKI, cAMP-dependent protein kinase inhibitor. Members of this family are extremely potent competitive inhibitors of camp-dependent protein kinase activity. These proteins interact with the catalytic subunit of the enzyme after the cAMP-induced | 3 genes |
| PARP_reg, Poly(ADP-ribose) polymerase, regulatory domain. Poly(ADP-ribose) polymerase catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affini | 3 genes |
| PRA1, PRA1 family protein. This family includes the PRA1 (Prenylated rab acceptor) protein. This family also includes the glutamate transporter EAAC1 interacting protein GTRAP3-18 | 3 genes |
| Pox_MCEL, mRNA capping enzyme. This family of enzymes are related to pfam03919 | 3 genes |
| PCRF, PCRF domain. This domain is found in peptide chain release factors | 3 genes |
| Peptidase_U34, Peptidase family U34 | 3 genes |
| Pellino, Pellino. Pellino is involved in Toll-like signalling pathways, and associates with the kinase domain of the Pelle Ser/Thr kinase | 3 genes |
| Pex2_Pex12, Pex2 / Pex12 amino terminal region. This region is the amino terminal part of the Pex2 and Pex12 peroxisomal biogenesis proteins. It contains two predicted transmembrane segments. This region is found to the C-terminus of a ring fi | 3 genes |
| Popeye, Popeye protein conserved region. The function of Popeye proteins is not well understood. They are predominantly expressed in cardiac and skeletal muscle. This family represents a conserved region which includes three potential transmem | 3 genes |
| PurA, PurA ssDNA and RNA-binding protein. This family represents most of the length of the protein | 3 genes |
| PAP_RNA-bind, Poly(A) polymerase predicted RNA binding domain. Based on its similarity structurally to the RNA recognition motif this domain is thought to be RNA binding | 3 genes |
| PAP_central, Poly(A) polymerase central domain. The central domain of Poly(A) polymerase shares structural similarity with the allosteric activity domain of ribonucleotide reductase R1, which comprises a four-helix bundle and a three-stranded | 3 genes |
| Pecanex_C, Pecanex protein (C-terminus). This family consists of C terminal region of the pecanex protein homologues. The pecanex protein is a maternal-effect neurogenic gene found in Drosophila | 3 genes |
| p25-alpha, p25-alpha. This family encodes a 25 kDa protein that is phosphorylated by a Ser/Thr-Pro kinase. It has been described as a brain specific protein, but it is found in Tetrahymena thermophila | 3 genes |
| Peptidase_S28, Serine carboxypeptidase S28. These serine proteases include several eukaryotic enzymes such as lysosomal Pro-X carboxypeptidase, dipeptidyl-peptidase II, and thymus-specific serine peptidase | 3 genes |
| PEX11, Peroxisomal biogenesis factor 11 (PEX11). This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple | 3 genes |
| Pro-MCH, Pro-melanin-concentrating hormone (Pro-MCH). This family consists of several mammalian pro-melanin-concentrating hormone (Pro-MCH) 1 and 2 proteins. Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic peptide that was first | 3 genes |
| protein-nucleus import, translocation, TAS | 3 genes |
| protein-glutamine gamma-glutamyltransferase activity, TAS | 3 genes |
| phosphoinositide 5-phosphatase activity, IEA | 3 genes |
| pantothenate kinase activity, IEA | 3 genes |
| peptide-aspartate beta-dioxygenase activity, IEA | 3 genes |
| phospholipase C activity, IEA | 3 genes |
| phosphopyruvate hydratase activity, TAS | 3 genes |
| phosphorylase activity, IEA | 3 genes |
| procollagen-proline 4-dioxygenase activity, TAS | 3 genes |
| protein kinase CK2 activity, TAS | 3 genes |
| phosphorylase kinase activity, TAS | 3 genes |
| protein-tyrosine kinase activity, ISS | 3 genes |
| protein-L-isoaspartate (D-aspartate) O-methyltransferase activity, IEA | 3 genes |
| phenylalanine-tRNA ligase activity, TAS | 3 genes |
| protein phosphatase inhibitor activity, NAS | 3 genes |
| protein binding, NR | 3 genes |
| phospholipid binding, IEA | 3 genes |
| peroxisomal membrane, IEA | 3 genes |
| pentose-phosphate shunt, IEA | 3 genes |
| purine ribonucleoside salvage, IEA | 3 genes |
| pyrimidine nucleotide metabolism, TAS | 3 genes |
| protein folding, NR | 3 genes |
| protein amino acid methylation, TAS | 3 genes |
| protein amino acid glycosylation, NR | 3 genes |
| phospholipid metabolism, NR | 3 genes |
| phosphatidylinositol biosynthesis, TAS | 3 genes |
| prostaglandin metabolism, TAS | 3 genes |
| potassium ion transport, ISS | 3 genes |
| phagocytosis, engulfment, TAS | 3 genes |
| pattern specification, TAS | 3 genes |
| pregnancy, NR | 3 genes |
| parturition, TAS | 3 genes |
| perception of sound, ISS | 3 genes |
| pre-mRNA splicing factor activity, IDA | 3 genes |
| peptide receptor activity, G-protein coupled, IEA | 3 genes |
| protein phosphatase type 2A regulator activity, IEA | 3 genes |
| protein phosphatase type 2A regulator activity, NAS | 3 genes |
| protein transport, NAS | 3 genes |
| potassium channel regulator activity, IDA | 3 genes |
| prefoldin complex, IEA | 3 genes |
| phosphatidylinositol 3-kinase activity, NAS | 3 genes |
| phosphorylation, IEA | 3 genes |
| protein processing, IEA | 3 genes |
| peroxisome division, IEA | 3 genes |
| phospholipid scrambling, NAS | 3 genes |
| phospholipid scramblase activity, NAS | 3 genes |
| protein amino acid geranylgeranylation, TAS | 3 genes |
| phospholipase A2 inhibitor activity, IEA | 3 genes |
| positive regulation of T-cell proliferation, IMP | 3 genes |
| phosphoric ester hydrolase activity, IEA | 3 genes |
| positive regulation of interleukin-2 biosynthesis, NAS | 3 genes |
| positive regulation of interleukin-6 biosynthesis, ISS | 3 genes |
| positive regulation of transcription, DNA-dependent, NAS | 3 genes |
| positive regulation of transcription, IDA | 3 genes |
| positive regulation of transcription from Pol II promoter, IDA | 3 genes |
| protein N-terminus binding, IPI | 3 genes |
| protein stabilization, ISS | 3 genes |
| PGK, Phosphoglycerate kinase | 2 genes |
| Prion, Prion/Doppel alpha-helical domain. The prion protein is thought to be the infectious agent that causes transmissible spongiform encephalopathies, such as scrapie and BSE. It is thought that the prion protein can exist in two different f | 2 genes |
| PGM_PMM_IV, Phosphoglucomutase/phosphomannomutase, C-terminal domain | 2 genes |
| PP-binding, Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This doma | 2 genes |
| Pyrophosphatase, Inorganic pyrophosphatase | 2 genes |
| PUF, Pumilio-family RNA binding repeat. Puf repeats (aka PUM-HD, Pumilio homology domain) are necessary and sufficient for sequence specific RNA binding in fly Pumilio and worm FBF-1 and FBF-2. Both proteins function as translational repressor | 2 genes |
| Peptidase_M22, Glycoprotease family | 2 genes |
| PEPCK, Phosphoenolpyruvate carboxykinase. Catalyses the formation of phosphoenolpyruvate by decarboxylation of oxaloacetate | 2 genes |
| ParA, ParA family ATPase | 2 genes |
| PNP_UDP_1, Phosphorylase family. Members of this family include: purine nucleoside phosphorylase (PNP) Uridine phosphorylase (UdRPase) 5'-methylthioadenosine phosphorylase (MTA phosphorylase) | 2 genes |
| PTN_MK_C, PTN/MK heparin-binding protein family, C-terminal domain | 2 genes |
| Parathyroid, Parathyroid hormone family | 2 genes |
| Pterin_4a, Pterin 4 alpha carbinolamine dehydratase. Pterin 4 alpha carbinolamine dehydratase is also known as DCoH (dimerisation cofactor of hepatocyte nuclear factor 1-alpha) | 2 genes |
| PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor | 2 genes |
| Peptidase_M2, Angiotensin-converting enzyme. Members of this family are dipeptidyl carboxydipeptidases (cleave carboxyl dipeptides) and most notably convert angiotensin I to angiotensin II. Many members of this family contain a tandem duplicat | 2 genes |
| Peptidase_M48, Peptidase family M48 | 2 genes |
| Peptidase_C15, Pyroglutamyl peptidase | 2 genes |
| PUA, PUA domain. The PUA domain named after Pseudouridine synthase and Archaeosine transglycosylase, was detected in archaeal and eukaryotic pseudouridine synthases, archaeal archaeosine synthases, a family of predicted ATPases that may be inv | 2 genes |
| Peptidase_C13, Peptidase C13 family. This family of peptidases is known as the hemoglobinase family because it contains a globin degrading enzyme from blood parasites. However, relatives are found in plants and other organisms that have other | 2 genes |
| Palm_thioest, Palmitoyl protein thioesterase | 2 genes |
| Peptidase_S15, X-Pro dipeptidyl-peptidase (S15 family) | 2 genes |
| PDH, Prephenate dehydrogenase. Members of this family are prephenate dehydrogenases EC:1.3.1.12 involved in tyrosine biosynthesis | 2 genes |
| PC4, Transcriptional Coactivator p15 (PC4). p15 has a bipartite structure composed of an amino-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain. The DNA-binding activity of the carboxy-terminal is disguised by the a | 2 genes |
| PAH, Paired amphipathic helix repeat. This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly relate | 2 genes |
| Peptidase_M17_N, Cytosol aminopeptidase family, N-terminal domain | 2 genes |
| PGM_PMM_III, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III | 2 genes |
| PK_C, Pyruvate kinase, alpha/beta domain | 2 genes |
| Peptidase_S9_N, Prolyl oligopeptidase, N-terminal beta-propeller domain. This unusual 7-stranded beta-propeller domain protects the catalytic triad of prolyl oligopeptidase (see pfam00326), excluding larger peptides and proteins from proteolys | 2 genes |
| PLA2_inh, Phospholipase A2 inhibitor | 2 genes |
| PFEMP, Plasmodium falciparum erythrocyte membrane protein (PFEMP). PfEMP1 has been identified as the rosetting ligand of the malaria parasite P. falciparum. Rosetting is the adhesion of infected erythrocytes with uninfected erythrocytes in the | 2 genes |
| PSS, Phosphatidyl serine synthase. Phosphatidyl serine synthase is also known as serine exchange enzyme. This family represents eukaryotic PSS I and II which are membrane bound proteins which catalyses the replacement of the head group of a ph | 2 genes |
| Pept_C1-like, Peptidase C1-like family. This family is closely related to the Peptidase_C1 family pfam00112, containing several prokaryotic and eukaryotic aminopeptidases and bleomycin hydrolases | 2 genes |
| PAE, Pectinacetylesterase | 2 genes |
| Paralemmin, Paralemmin | 2 genes |
| PMM, Eukaryotic phosphomannomutase. This enzyme EC:5.4.2.8 is involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions | 2 genes |
| PRP38, PRP38 family. Members of this family are related to the pre mRNA splicing factor PRP38 from yeast. Therefore all the members of this family could be involved in splicing. This conserved region could be involved in RNA binding. The putat | 2 genes |
| PAF-AH_p_II, Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II. Platelet-activating factor acetylhydrolase (PAF-AH) is a subfamily of phospholipases A2, responsible for inactivation of platelet-activating factor throu | 2 genes |
| Paxillin, Paxillin family | 2 genes |
| PHF5, PHF5-like protein. This family of proteins the superfamily of PHD-finger proteins. At least one example, from mouse, may act as a chromatin-associated protein | 2 genes |
| PSP, PSP. Proline rich domain found in numerous spliceosome associated proteins | 2 genes |
| P21-Arc, P21-ARC (ARP2/3 complex 21 kDa subunit). The seven component ARP2/3 actin-organising complex is involved in actin assembly and function | 2 genes |
| PDCD2_C, Programmed cell death protein 2, C-terminal putative domain | 2 genes |
| PDGF_N, Platelet-derived growth factor, N terminal region. This family consists of the amino terminal regions of platelet-derived growth factor (PDGF, pfam00341) A and B chains | 2 genes |
| P16-Arc, ARP2/3 complex 16 kDa subunit (p16-Arc). The Arp2/3 protein complex has been implicated in the control of actin polymerisation. The human complex consists of seven subunits which include the actin related proteins Arp2 and Arp3, and f | 2 genes |
| PDE6_gamma, Retinal cGMP phosphodiesterase, gamma subunit. Retinal rod and cone cGMP phosphodiesterases function as the effector enzymes in the vertebrate visual transduction cascade. This family represents the inhibitory gamma subunit, which | 2 genes |
| PT, PT repeat. This short repeat is composed on the tetrapeptide XPTX. This repeat is found in a variety of proteins, however it is not clear if these repeats are homologous to each other. The alignment represents nine copies of this repeat | 2 genes |
| PTN_MK_N, PTN/MK heparin-binding protein family, N-terminal domain | 2 genes |
| Pox_ser-thr_kin, Poxvirus serine/threonine protein kinase | 2 genes |
| Peptidase_M43, Pregnancy-associated plasma protein-A. Pregnancy-associated plasma protein A (PAPP-A) is a metallo-protease belonging to Merops family M43. It cleaves insulin-like growth factor (IGF) binding protein-4 (IGFBP-4), causing a drama | 2 genes |
| PhyH, Phytanoyl-CoA dioxygenase (PhyH). This family is made up of several eukaryotic phytanoyl-CoA dioxygenase (PhyH) proteins as well as a number of bacterial deoxygenases. PhyH is a peroxisomal enzyme catalysing the first step of phytanic ac | 2 genes |
| PSP94, Beta-microseminoprotein (PSP-94). This family consists of the mammalian specific protein beta-microseminoprotein. Prostatic secretory protein of 94 amino acids (PSP94), also called beta-microseminoprotein, is a small, nonglycosylated pr | 2 genes |
| Phospholip_A2_2, Phospholipase A2. This family consists of several phospholipase A2 like proteins mostly from insects | 2 genes |
| P_denitri_CobS, Cobalamin biosynthesis protein CobS. This family consists of several bacterial CobS proteins which are related to the Pseudomonas denitrificans CobS. It is thought that CobS is involved in cobalt insertion-mediating reactions. | 2 genes |
| Pex24p, Integral peroxisomal membrane peroxin. Peroxisomes play diverse roles in the cell, compartmentalising many activities related to lipid metabolism and functioning in the decomposition of toxic hydrogen peroxide. Sequence similarity was | 2 genes |
| PCAF_N, PCAF (P300/CBP-associated factor) N-terminal domain. This region is spliced out of hsGCN5 isoform 2. It is predicted to be of a mixed alpha/beta fold - though predominantly helical | 2 genes |
| PRF, Plethodontid receptivity factor PRF. This family consists of several plethodontid receptivity factor (PRF) proteins which seem to be specific to Plethodon jordani (Jordan's salamander). PRF is a courtship pheromone produced by males incre | 2 genes |
| PLA2G12, Group XII secretory phospholipase A2 precursor (PLA2G12). This family consists of several group XII secretory phospholipase A2 precursor (PLA2G12) (EC:3.1.1.4) proteins. Group XII and group V PLA(2)s are thought to participate in help | 2 genes |
| Paip2, Polyadenylate binding protein-interacting protein 2 (Paip2). This family consists of several eukaryotic polyadenylate binding protein-interacting protein 2 (Paip2) sequences. The cap structure and the poly(A) tail of eukaryotic mRNAs ac | 2 genes |
| PDCD9, Mitochondrial 28S ribosomal protein S30 (PDCD9). This family consists of several eukaryotic mitochondrial 28S ribosomal protein S30 (or programmed cell death protein 9 PDCD9) sequences. The exact function of this family is unknown altho | 2 genes |
| Prenylcys_lyase, Prenylcysteine lyase. This family contains prenylcysteine lyases (EC:1.8.3.5) that are approximately 500 residues long. Prenylcysteine lyase is a FAD-dependent thioether oxidase that degrades a variety of prenylcysteines, prod | 2 genes |
| PCEMA1, Acidic phosphoprotein precursor PCEMA1. This family consists of several acidic phosphoprotein precursor PCEMA1 sequences which appear to be found exclusively in Plasmodium chabaudi. PCEMA1 is an antigen that is associated with the memb | 2 genes |
| protein phosphatase type 2A activity, NR | 2 genes |
| protein phosphatase type 2A complex, NAS | 2 genes |
| protein phosphatase type 2A complex, TAS | 2 genes |
| protein phosphatase type 1 activity, TAS | 2 genes |
| pericentriolar material, TAS | 2 genes |
| phospholipid-translocating ATPase activity, NAS | 2 genes |
| peptidyl-dipeptidase A activity, IEA | 2 genes |
| phosphoinositide phospholipase C activity, NAS | 2 genes |
| pancreatic ribonuclease activity, TAS | 2 genes |
| phosphodiesterase I activity, TAS | 2 genes |
| phosphomannomutase activity, TAS | 2 genes |
| phosphogluconate dehydrogenase (decarboxylating) activity, IEA | 2 genes |
| phospholipase A2 activity, NAS | 2 genes |
| phospholipase D activity, TAS | 2 genes |
| phosphopyruvate hydratase activity, IEA | 2 genes |
| polynucleotide adenylyltransferase activity, IEA | 2 genes |
| proline dehydrogenase activity, IEA | 2 genes |
| propionyl-CoA carboxylase activity, TAS | 2 genes |
| protein farnesyltransferase activity, TAS | 2 genes |
| protein-arginine deiminase activity, IEA | 2 genes |
| protein-arginine deiminase activity, TAS | 2 genes |
| phosphorylase kinase activity, NR | 2 genes |
| phosphoprotein phosphatase activity, TAS | 2 genes |
| protein serine/threonine phosphatase activity, IDA | 2 genes |
| protein serine/threonine phosphatase activity, ISS | 2 genes |
| protein tyrosine phosphatase activity, IDA | 2 genes |
| protein tyrosine phosphatase activity, ISS | 2 genes |
| prenylated protein tyrosine phosphatase activity, TAS | 2 genes |
| pyruvate dehydrogenase (acetyl-transferring) activity, TAS | 2 genes |
| pyruvate kinase activity, TAS | 2 genes |
| protein phosphatase inhibitor activity, IEA | 2 genes |
| parathyroid hormone receptor activity, TAS | 2 genes |
| platelet-derived growth factor receptor binding, TAS | 2 genes |
| profilin binding, ISS | 2 genes |
| phospholipid binding, IDA | 2 genes |
| phosphatidylinositol binding, NAS | 2 genes |
| phosphatidylinositol binding, TAS | 2 genes |
| phosphatidylinositol-4,5-bisphosphate binding, NAS | 2 genes |
| peroxisome, NAS | 2 genes |
| peroxisomal membrane, NR | 2 genes |
| peroxisomal membrane, TAS | 2 genes |
| polar microtubule, IDA | 2 genes |
| proteasome core complex (sensu Eukarya), NAS | 2 genes |
| plus-end kinesin complex, TAS | 2 genes |
| phosphorylase kinase complex, IEA | 2 genes |
| polysaccharide metabolism, TAS | 2 genes |
| pyruvate metabolism, NR | 2 genes |
| postreplication repair, TAS | 2 genes |
| phenylalanyl-tRNA aminoacylation, NR | 2 genes |
| protein amino acid ADP-ribosylation, NAS | 2 genes |
| protein amino acid deacetylation, NR | 2 genes |
| protein amino acid sulfation, NR | 2 genes |
| protein amino acid sulfation, TAS | 2 genes |
| peptidyl-tyrosine sulfation, TAS | 2 genes |
| proteolysis and peptidolysis, IDA | 2 genes |
| proteolysis and peptidolysis, ISS | 2 genes |
| protein deglycosylation, TAS | 2 genes |
| peptide metabolism, TAS | 2 genes |
| proline biosynthesis, TAS | 2 genes |
| proline catabolism, IEA | 2 genes |
| polyamine metabolism, TAS | 2 genes |
| polyamine biosynthesis, IEA | 2 genes |
| protein targeting, ISS | 2 genes |
| protein-membrane targeting, NAS | 2 genes |
| protein-ER retention, TAS | 2 genes |
| protein-lysosome targeting, TAS | 2 genes |
| protein-mitochondrial targeting, IEA | 2 genes |
| protein-mitochondrial targeting, NAS | 2 genes |
| phosphatidic acid biosynthesis, TAS | 2 genes |
| phosphatidylcholine biosynthesis, TAS | 2 genes |
| phosphatidylserine biosynthesis, IEA | 2 genes |
| prostaglandin metabolism, IEA | 2 genes |
| porphyrin biosynthesis, IEA | 2 genes |
| potassium ion transport, IDA | 2 genes |
| post-chaperonin tubulin folding pathway, TAS | 2 genes |
| protein kinase C activation, NAS | 2 genes |
| protein kinase cascade, NAS | 2 genes |
| pan-neural process, TAS | 2 genes |
| physiological process, NAS | 2 genes |
| perception of sound, NR | 2 genes |
| protein localization, TAS | 2 genes |
| protein tyrosine/threonine phosphatase activity, TAS | 2 genes |
| palmitoyl-(protein) hydrolase activity, IEA | 2 genes |
| procollagen-lysine 5-dioxygenase activity, IEA | 2 genes |
| procollagen-lysine 5-dioxygenase activity, TAS | 2 genes |
| protein-tyrosine sulfotransferase activity, TAS | 2 genes |
| phosphatidylcholine transporter activity, TAS | 2 genes |
| proteasome activator complex, IEA | 2 genes |
| proteasome activator activity, IEA | 2 genes |
| protein transporter activity, IMP | 2 genes |
| protein transporter activity, NR | 2 genes |
| protein phosphatase type 2A regulator activity, ISS | 2 genes |
| phosphorylase kinase regulator activity, NR | 2 genes |
| phospholipid biosynthesis, TAS | 2 genes |
| phosphoglycolate phosphatase activity, IEA | 2 genes |
| phospholipase A1 activity, TAS | 2 genes |
| purine base biosynthesis, IEA | 2 genes |
| purine base biosynthesis, TAS | 2 genes |
| pyrimidine ribonucleotide biosynthesis, TAS | 2 genes |
| protein secretion, NAS | 2 genes |
| phospholipid catabolism, IEA | 2 genes |
| pathogenesis, NAS | 2 genes |
| pathogenesis, TAS | 2 genes |
| protein transport, IMP | 2 genes |
| potassium ion transporter activity, TAS | 2 genes |
| peptide:hydrogen symporter activity, TAS | 2 genes |
| potassium:chloride symporter activity, NAS | 2 genes |
| proton transport, NAS | 2 genes |
| prefoldin complex, NAS | 2 genes |
| phosphorylation, TAS | 2 genes |
| pyrophosphatase activity, IEA | 2 genes |
| peptide hormone processing, NAS | 2 genes |
| protein-hormone receptor activity, IEA | 2 genes |
| protein ubiquitination, TAS | 2 genes |
| protein deubiquitination, IDA | 2 genes |
| phosphoric monoester hydrolase activity, IEA | 2 genes |
| peptidyl-amino acid modification, IEA | 2 genes |
| protein amino acid farnesylation, TAS | 2 genes |
| prothoracicotrophic hormone activity, IEA | 2 genes |
| protein kinase binding, NAS | 2 genes |
| PDZ domain binding, IPI | 2 genes |
| PDZ domain binding, ISS | 2 genes |
| proteoglycan biosynthesis, ISS | 2 genes |
| platelet activation, IDA | 2 genes |
| platelet activation, ISS | 2 genes |
| platelet activation, TAS | 2 genes |
| protein phosphatase 2B binding, NAS | 2 genes |
| positive regulation of actin filament polymerization, IMP | 2 genes |
| positive regulation of T-cell proliferation, TAS | 2 genes |
| phosphate binding, NAS | 2 genes |
| presynaptic membrane, NAS | 2 genes |
| protein homodimerization activity, TAS | 2 genes |
| protein homooligomerization activity, IPI | 2 genes |
| protein homooligomerization activity, NAS | 2 genes |
| positive regulation of apoptosis, ISS | 2 genes |
| positive regulation of apoptosis, NAS | 2 genes |
| positive regulation of enzyme activity, IEA | 2 genes |
| positive regulation of innate immune response, TAS | 2 genes |
| postsynaptic membrane, IDA | 2 genes |
| phagocytic vesicle, ISS | 2 genes |
| positive regulation of interleukin-13 biosynthesis, ISS | 2 genes |
| positive regulation of interleukin-8 biosynthesis, IDA | 2 genes |
| positive regulation of gluconeogenesis, ISS | 2 genes |
| positive regulation of angiogenesis, IDA | 2 genes |
| positive regulation of anti-apoptosis, NAS | 2 genes |
| positive regulation of cell adhesion, IDA | 2 genes |
| positive regulation of lipid metabolism, ISS | 2 genes |
| positive regulation of transcription, DNA-dependent, ISS | 2 genes |
| positive regulation of fatty acid oxidation, ISS | 2 genes |
| positive regulation of RAS protein signal transduction, IDA | 2 genes |
| positive regulation of follicle-stimulating hormone secretion, TAS | 2 genes |
| peptide antigen transport, NAS | 2 genes |
| protein heterodimerization activity, TAS | 2 genes |
| positive regulation of phagocytosis, IDA | 2 genes |
| protein stabilization, NAS | 2 genes |
| protein kinase A binding, NAS | 2 genes |
| PAL, Phenylalanine and histidine ammonia-lyase | 1 genes |
| PGI, Phosphoglucose isomerase. Phosphoglucose isomerase catalyses the interconversion of glucose-6-phosphate and fructose-6-phosphate | 1 genes |
| PCNA_N, Proliferating cell nuclear antigen, N-terminal domain. N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA | 1 genes |
| Pentapeptide, Pentapeptide repeats (8 copies). These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK. The function of these repeats is unknown. The structure of this repeat has been predicted to be | 1 genes |
| Pterin_bind, Pterin binding enzyme. This family includes a variety of pterin binding enzymes that all adopt a TIM barrel fold. The family includes dihydropteroate synthase EC:2.5.1.15 as well as a group methyltransferase enzymes including meth | 1 genes |
| Peptidase_C4, Peptidase family C4. This peptidase is present in the nuclear inclusion protein of potyviruses | 1 genes |
| Pept_tRNA_hydro, Peptidyl-tRNA hydrolase | 1 genes |
| PMI_typeI, Phosphomannose isomerase type I | 1 genes |
| Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase | 1 genes |
| Pep_deformylase, Polypeptide deformylase | 1 genes |
| Porphobil_deam, Porphobilinogen deaminase, dipyromethane cofactor binding domain | 1 genes |
| Peptidase_M8, Leishmanolysin | 1 genes |
| PAPS_reduct, Phosphoadenosine phosphosulfate reductase family. This domain is found in phosphoadenosine phosphosulfate (PAPS) reductase enzymes or PAPS sulfotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfa | 1 genes |
| PPR, PPR repeat. This repeat has no known function. It is about 35 amino acids long and found in up to 18 copies in some proteins. This family appears to be greatly expanded in plants. This repeat occurs in PET309 that may be involved in RNA s | 1 genes |
| PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine | 1 genes |
| PolyA_pol, Poly A polymerase family. This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that ad | 1 genes |
| Paramyxo_P, Paramyxovirus P phosphoprotein. This family consists of paramyxovirus P phosphoprotein from sendai virus and human and bovine parainfluenza viruses. The P protein is an essential part of the viral RNA polymerase complex formed form | 1 genes |
| PC_rep, Proteasome/cyclosome repeat | 1 genes |
| PTS_2-RNA, RNA 2'-phosphotransferase, Tpt1 / KptA family. Tpt1 catalyses the last step of tRNA splicing in yeast. It transfers the splice junction 2'-phosphate from ligated tRNA to NAD, to produce ADP-ribose 1"-2"-cyclic phosphate. This is pre | 1 genes |
| PTE, Phosphotriesterase family | 1 genes |
| Peptidase_M18, Aminopeptidase I zinc metalloprotease (M18) | 1 genes |
| Peptidase_M50, Peptidase family M50 | 1 genes |
| PNTB, NAD(P) transhydrogenase beta subunit. This family corresponds to the beta subunit of NADP transhydrogenase in prokaryotes, and either the protein N- or C terminal in eukaryotes. The domain is often found in conjunction with pfam01262. Py | 1 genes |
| Pur_DNA_glyco, Methylpurine-DNA glycosylase (MPG). Methylpurine-DNA glycosylase is a base excision-repair protein. It is responsible for the hydrolysis of the deoxyribose N-glycosidic bond, excising 3-methyladenine and 3-methylguanine from dam | 1 genes |
| PYC_OADA, Conserved carboxylase domain. This domain represents a conserved region in pyruvate carboxylase (PYC), oxaloacetate decarboxylase alpha chain (OADA), and transcarboxylase 5s subunit. The domain is found adjacent to the HMGL-like doma | 1 genes |
| PhzC-PhzF, Phenazine biosynthesis-like protein. PhzC/PhzF is involved in dimerisation of two 2,3-dihydro-3-oxo-anthranilic acid molecules to create PCA by P. fluorescens. This family appears to be distantly related to pfam01678, including cont | 1 genes |
| PS_Dcarbxylase, Phosphatidylserine decarboxylase. This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyse the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxyla | 1 genes |
| Pirin, Pirin. This family consists of Pirin proteins from both eukaryotes and prokaryotes. The function of Pirin is unknown but the gene coding for this protein is known to be expressed in all tissues in the human body although it is expressed | 1 genes |
| PCNA_C, Proliferating cell nuclear antigen, C-terminal domain. N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA | 1 genes |
| Prp18, Prp18 domain. The splicing factor Prp18 is required for the second step of pre-mRNA splicing. The structure of a large fragment of the Saccharomyces cerevisiae Prp18 is known. This fragment is fully active in yeast splicing in vitro and | 1 genes |
| PTPA, Phosphotyrosyl phosphate activator (PTPA) protein. Phosphotyrosyl phosphatase activator (PTPA) proteins stimulate the phosphotyrosyl phosphatase (PTPase) activity of the dimeric form of protein phosphatase 2A (PP2A). PTPase activity in P | 1 genes |
| Plus-3, Plus-3 domain. This domain is about 90 residues in length and is often found associated with the pfam02213 domain. The function of this domain is uncertain. It is possible that this domain is involved in DNA binding as it has three con | 1 genes |
| Peptidase_C50, Peptidase family C50 | 1 genes |
| Peptidase_M49, Peptidase family M49 | 1 genes |
| Peptidase_S41, Peptidase family S41B | 1 genes |
| Psf1, Partner of SLD five, PSF1. The GINS complex is essential for initiation of DNA replication in Xenopus egg extracts. This 100 kD stable complex includes Sld5, Psf1, Psf2, and Psf3. Homologues of these components are found also in yeasts a | 1 genes |
| PNPase, Polyribonucleotide nucleotidyltransferase, RNA binding domain. This family contains the RNA binding domain of Polyribonucleotide nucleotidyltransferase (PNPase) PNPase is involved in mRNA degradation in a 3'-5' direction | 1 genes |
| PkinA_anch, Protein kinase A anchor | 1 genes |
| Porphobil_deamC, Porphobilinogen deaminase, C-terminal domain | 1 genes |
| P34-Arc, Arp2/3 complex, 34 kD subunit p34-Arc. Arp2/3 protein complex has been implicated in the control of actin polymerisation in cells. The human complex consists of seven subunits which include the actin related Arp2 and Arp3, and five ot | 1 genes |
| PWP2, Periodic tryptophan protein 2 WD repeat associated presumed domain | 1 genes |
| Per1, Per1-like. A member of this family has been implemented in protein processing in the endoplasmic reticulum | 1 genes |
| Peroxin-13_N, Peroxin 13, N-terminal. Both termini of the Peroxin-13 are oriented to the cytosol. Peroxin-13 is required for peroxisomal association of peroxin-14 | 1 genes |
| Psf2, Partner of SLD five, PSF2. A eukaryotic specific domain of undetermined function.` The GINS complex is essential for initiation of DNA replication in Xenopus egg extracts. This 100 kD stable complex includes Sld5, Psf1, Psf2, and Psf3. H | 1 genes |
| PEMT, Phospholipid methyltransferase. The S. cerevisiae phospholipid methyltransferase (EC:2.1.1.16) has a broad substrate specificity of unsaturated phospholipids | 1 genes |
| Phospholamban, Phospholamban. The regulation of calcium levels across the membrane of the sarcoplasmic reticulum involves the interplay of many membrane proteins. Phospholamban is a 52 residue integral membrane protein that is involved in reve | 1 genes |
| P-mevalo_kinase, Phosphomevalonate kinase. Phosphomevalonate kinase (EC:2.7.4.2) catalyses the phosphorylation of 5-phosphomevalonate into 5-diphosphomevalonate, an essential step in isoprenoid biosynthesis via the mevalonate pathway. This fam | 1 genes |
| Pox_G5, Poxvirus G5 protein | 1 genes |
| Pex19, Pex19 protein family | 1 genes |
| Pex14_N, Peroxisomal membrane anchor protein (Pex14p) conserved region. Family of peroxisomal membrane anchor proteins which bind the PTS1 (peroxisomal targeting signal) receptor and are required for the import of PTS1-containing proteins into | 1 genes |
| Pinin_SDK_memA, pinin/SDK/memA/ protein conserved region. Members of this family have very varied localisations within the eukaryotic cell. pinin is known to localise at the desmosomes and is implicated in anchoring intermediate filaments to t | 1 genes |
| Pinin_SDK_N, pinin/SDK conserved region. SDK2/3 is localised in nuclear speckles where as pinin is known to localise at the desmosomes where it is thought to be involved in anchoring intermediate filaments to the desmosomal plaque. The role of | 1 genes |
| PAPA-1, PAPA-1-like conserved region. Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein | 1 genes |
| Peroxin-3, Peroxin-3. Peroxin-3 is a peroxisomal protein. It is thought to be involve in membrane vesicle assembly prior to the translocation of matrix proteins | 1 genes |
| Pox_IFNR, Poxvirus interferon gamma receptor | 1 genes |
| PigN, Phosphatidylinositolglycan class N (PIG-N). Phosphatidylinositolglycan class N (PIG-N) is a mammalian homologue of the yeast protein MCD4P and is expressed in the endoplasmic reticulum. PIG-N is essential for glycosylphosphatidylinositol | 1 genes |
| PARG_cat, Poly (ADP-ribose) glycohydrolase (PARG). Poly(ADP-ribose) glycohydrolase (PARG), is a ubiquitously expressed exo- and endoglycohydrolase which mediates oxidative and excitotoxic neuronal death | 1 genes |
| Pep3_Vps18, Pep3/Vps18/deep orange family. This region is found in a number of protein identified as involved in golgi function and vacuolar sorting. The molecular function of this region is unknown. The members of this family contain a C-term | 1 genes |
| Peptidase_M42, M42 glutamyl aminopeptidase. These peptidases are found in Archaea and Bacteria. The example in Lactococcus lactis, PepA, aids growth on milk. Pyrococcus horikoshii contain a thermostable de-blocking aminopeptidase member of thi | 1 genes |
| Pro_racemase, Proline racemase. This family consists of proline racemase (EC 5.1.1.4) proteins which catalyse the interconversion of L- and D-proline in bacteria. This family also contains several similar eukaryotic proteins including a sequen | 1 genes |
| Pox_vIL-18BP, Orthopoxvirus interleukin 18 binding protein. Interleukin-18 (IL-18) is a proinflammatory cytokine that plays a key role in the activation of natural killer and T helper 1 cell responses principally by inducing interferon-gamma ( | 1 genes |
| Peptidase_M47, Zincin metallopeptidase M47. The zincins are a superfamily of structurally-related zinc-binding metallopeptidases that play a major role in a wide range of biological processes including pattern formation, growth factor activati | 1 genes |
| PAXNEB, PAXNEB protein. PAXNEB or PAX6 neighbour is found in several eukaryotic organisms. The function of this protein is unknown | 1 genes |
| Pirin_C, Pirin C-terminal region. This region is found the C-terminal half of the Pirin protein | 1 genes |
| Podoplanin, Podoplanin. This family consists of several mammalian podoplanin like proteins which are thought to control specifically the unique shape of podocytes | 1 genes |
| PRP1_N, PRP1 splicing factor, N-terminal. This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is | 1 genes |
| Psf3, Partner of SLD five, PSF3. The GINS complex is essential for initiation of DNA replication in Xenopus egg extracts. This 100 kD stable complex includes Sld5, Psf1, Psf2, and Psf3. Homologues of these components are found also in yeasts a | 1 genes |
| Polyoma_lg_T_C, Polyomavirus large T antigen C-terminus | 1 genes |
| PIG-F, Phospho-ethanolamine N-methyltransferase. Phospho-ethanolamine N-methyltransferase is involved in glycosylphosphatidylinositol (GPI) anchor biosynthesis | 1 genes |
| PIG-U, GPI transamidase subunit PIG-U. Many eukaryotic proteins are anchored to the cell surface via glycosylphosphatidylinositol (GPI), which is posttranslationally attached to the carboxyl-terminus by GPI transamidase. The mammalian GPI tran | 1 genes |
| Pescadillo_N, Pescadillo N-terminus. This family represents the N-terminal region of Pescadillo. Pescadillo protein localises to distinct substructures of the interphase nucleus including nucleoli, the site of ribosome biogenesis. During mitos | 1 genes |
| PrkA, PrkA serine protein kinase. This is a family of PrkA bacterial and archaeal serine kinases approximately 630 residues long. PrkA possesses the A-motif of nucleotide-binding proteins and exhibits distant homology to eukaryotic protein kin | 1 genes |
| Pkip-1, Pkip-1 protein. This family consists of several Pkip-1 proteins which seem to be specific to Nucleopolyhedroviruses. The function of this family is unknown although it has been found that Pkip-1 is not essential for virus replication i | 1 genes |
| Put_Phosphatase, Putative Phosphatase. This family contains a number of putative eukaryotic acid phosphatases. Some family members represent the products of the PSI14 phosphatase family in Lycopersicon esculentum (Tomato) | 1 genes |
| POP1, Ribonucleases P/MRP protein subunit POP1. This family represents a conserved region approximately 150 residues long located towards the N-terminus of the POP1 subunit that is common to both the RNase MRP and RNase P ribonucleoproteins (E | 1 genes |
| Pex26, Pex26 protein. This family consists of Pex26 and related mammalian proteins. Pex26 is a type II peroxisomal membrane protein which recruits Pex6-Pex1 complexes to peroxisomes. Mutations in Pex26 can lead to human disorders | 1 genes |
| PBP_sp32, Proacrosin binding protein sp32. This family consists of several mammalian specific proacrosin binding protein sp32 sequences. sp32 is a sperm specific protein which is known to bind with with 55- and 53-kDa proacrosins and the 49-kD | 1 genes |
| ProSAAS, ProSAAS precursor. This family consists of several mammalian proSAAS precursor proteins. ProSAAS mRNA is expressed primarily in brain and other neuroendocrine tissues (pituitary, adrenal, pancreas); within brain, the mRNA is broadly d | 1 genes |
| P19Arf_N, Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus. This family represents the N-terminus (approximately 50 residues) of cyclin-dependent kinase inhibitor 2a p19Arf, which seems to be restricted to mammals. This is a tumour-suppr | 1 genes |
| Pro-NT_NN, Neurotensin/neuromedin N precursor. This family contains the precursor of bacterial neurotensin/neuromedin N (approximately 170 residues long). This the common precursor of two biologically active related peptides, neurotensin and n | 1 genes |
| protein-nucleus import, docking, ISS | 1 genes |
| protein-nucleus import, docking, TAS | 1 genes |
| protein-nucleus import, translocation, NAS | 1 genes |
| protein-nucleus import, translocation, NR | 1 genes |
| polarisome, ISS | 1 genes |
| protein phosphatase type 2A activity, IDA | 1 genes |
| protein phosphatase type 2A activity, ISS | 1 genes |
| protein phosphatase type 2A complex, IDA | 1 genes |
| protein phosphatase type 1 complex, TAS | 1 genes |
| protein polyubiquitination, IDA | 1 genes |
| protein polyubiquitination, TAS | 1 genes |
| proteasome complex (sensu Eukarya), NAS | 1 genes |
| proteasome complex (sensu Eukarya), NR | 1 genes |
| prostaglandin biosynthesis, IDA | 1 genes |
| prostaglandin biosynthesis, ISS | 1 genes |
| peptide amidation, ISS | 1 genes |
| pseudouridine synthesis, NAS | 1 genes |
| patterning of blood vessels, ISS | 1 genes |
| prenylcysteine oxidase activity, IEA | 1 genes |
| P-element binding, TAS | 1 genes |
| Pol II transcription termination factor activity, TAS | 1 genes |
| protein disulfide isomerase activity, IDA | 1 genes |
| protein disulfide isomerase activity, IEA | 1 genes |
| plasma kallikrein activity, TAS | 1 genes |
| protein C (activated) activity, TAS | 1 genes |
| protein-glutamine gamma-glutamyltransferase activity, NAS | 1 genes |
| pyroglutamyl-peptidase I activity, IEA | 1 genes |
| peptidyl-dipeptidase A activity, TAS | 1 genes |
| pancreatic elastase II activity, IEA | 1 genes |
| pancreatic elastase II activity, TAS | 1 genes |
| plasmin activity, NR | 1 genes |
| plasmin activity, TAS | 1 genes |
| proprotein convertase 1 activity, IEA | 1 genes |
| proprotein convertase 2 activity, IEA | 1 genes |
| prolyl oligopeptidase activity, TAS | 1 genes |
| phosphoinositide phospholipase C activity, IDA | 1 genes |
| phosphoinositide phospholipase C activity, ISS | 1 genes |
| phosphoinositide 5-phosphatase activity, TAS | 1 genes |
| peptidylglycine monooxygenase activity, NAS | 1 genes |
| peptidylglycine monooxygenase activity, TAS | 1 genes |
| phenylalanine 4-monooxygenase activity, TAS | 1 genes |
| pancreatic ribonuclease activity, NAS | 1 genes |
| pantetheine-phosphate adenylyltransferase activity, IEA | 1 genes |
| peptide-aspartate beta-dioxygenase activity, TAS | 1 genes |
| peroxidase activity, ISS | 1 genes |
| peroxidase activity, NAS | 1 genes |
| phenylethanolamine N-methyltransferase activity, TAS | 1 genes |
| phosphatidate cytidylyltransferase activity, IEA | 1 genes |
| phosphatidate cytidylyltransferase activity, NAS | 1 genes |
| phosphatidylcholine-sterol O-acyltransferase activity, IEA | 1 genes |
| phosphatidylcholine-sterol O-acyltransferase activity, NAS | 1 genes |
| phosphatidylethanolamine N-methyltransferase activity, TAS | 1 genes |
| phosphatidylserine decarboxylase activity, IEA | 1 genes |
| phosphoacetylglucosamine mutase activity, IDA | 1 genes |
| phosphoenolpyruvate carboxykinase (GTP) activity, IEA | 1 genes |
| phosphoenolpyruvate carboxykinase (GTP) activity, TAS | 1 genes |
| phosphoglucomutase activity, IDA | 1 genes |
| phosphoglycerate dehydrogenase activity, TAS | 1 genes |
| phosphoglycerate kinase activity, IEA | 1 genes |
| phosphoglycerate kinase activity, NAS | 1 genes |
| phosphoglycerate kinase activity, TAS | 1 genes |
| phosphoglycerate mutase activity, NAS | 1 genes |
| phosphoglycerate mutase activity, TAS | 1 genes |
| phospholipase activity, IEA | 1 genes |
| phospholipase A2 activity, IDA | 1 genes |
| phospholipase C activity, TAS | 1 genes |
| phosphomevalonate kinase activity, TAS | 1 genes |
| phosphopantothenate-cysteine ligase activity, IEA | 1 genes |
| phosphoribosylamine-glycine ligase activity, IEA | 1 genes |
| phosphoribosylaminoimidazole carboxylase activity, IEA | 1 genes |
| phosphoribosylaminoimidazolesuccinocarboxamide synthase activity, TAS | 1 genes |
| phosphoribosylformylglycinamidine cyclo-ligase activity, IEA | 1 genes |
| phosphoribosylformylglycinamidine synthase activity, IEP | 1 genes |
| phosphoribosylaminoimidazolecarboxamide formyltransferase activity, TAS | 1 genes |
| phosphoribosylglycinamide formyltransferase activity, TAS | 1 genes |
| phosphorylase activity, TAS | 1 genes |
| phosphoserine phosphatase activity, TAS | 1 genes |
| phosphoserine transaminase activity, NAS | 1 genes |
| poly(ADP-ribose) glycohydrolase activity, TAS | 1 genes |
| polynucleotide 5'-phosphatase activity, IEA | 1 genes |
| polypeptide N-acetylgalactosaminyltransferase activity, NAS | 1 genes |
| porphobilinogen synthase activity, TAS | 1 genes |
| proline dehydrogenase activity, TAS | 1 genes |
| protein geranylgeranyltransferase activity, TAS | 1 genes |
| prostaglandin-endoperoxide synthase activity, NAS | 1 genes |
| prostaglandin-endoperoxide synthase activity, TAS | 1 genes |
| prostaglandin-D synthase activity, IEA | 1 genes |
| prostaglandin-D synthase activity, ISS | 1 genes |
| prostaglandin-D synthase activity, NR | 1 genes |
| prostaglandin-D synthase activity, TAS | 1 genes |
| protein-S-isoprenylcysteine O-methyltransferase activity, IEA | 1 genes |
| protein kinase activity, NR | 1 genes |
| protein kinase CK2 activity, NAS | 1 genes |
| phosphorylase kinase activity, NAS | 1 genes |
| protein-lysine 6-oxidase activity, NAS | 1 genes |
| protein-lysine 6-oxidase activity, TAS | 1 genes |
| protein tyrosine phosphatase activity, NR | 1 genes |
| prenylated protein tyrosine phosphatase activity, NR | 1 genes |
| protoporphyrinogen oxidase activity, TAS | 1 genes |
| pseudouridylate synthase activity, NAS | 1 genes |
| purine-nucleoside phosphorylase activity, TAS | 1 genes |
| pyridoxamine-phosphate oxidase activity, IEA | 1 genes |
| pyrroline-5-carboxylate reductase activity, TAS | 1 genes |
| pyruvate carboxylase activity, TAS | 1 genes |
| pyruvate dehydrogenase (acetyl-transferring) activity, IEA | 1 genes |
| pyruvate kinase activity, NAS | 1 genes |
| proline-tRNA ligase activity, IEA | 1 genes |
| phospholipase inhibitor activity, NAS | 1 genes |
| protein kinase inhibitor activity, IEA | 1 genes |
| protein phosphatase inhibitor activity, IDA | 1 genes |
| prolactin receptor activity, ISS | 1 genes |
| prolactin receptor activity, NAS | 1 genes |
| prostaglandin D receptor activity, NAS | 1 genes |
| prostaglandin E receptor activity, NAS | 1 genes |
| prostaglandin F receptor activity, TAS | 1 genes |
| prostaglandin I receptor activity, TAS | 1 genes |
| platelet-derived growth factor receptor activity, TAS | 1 genes |
| platelet-derived growth factor alpha-receptor activity, TAS | 1 genes |
| platelet-derived growth factor beta-receptor activity, TAS | 1 genes |
| peroxisome targeting signal-1 receptor activity, TAS | 1 genes |
| peroxisome targeting signal-2 receptor activity, TAS | 1 genes |
| patched binding, NAS | 1 genes |
| prolactin receptor binding, NAS | 1 genes |
| prolactin receptor binding, TAS | 1 genes |
| platelet-derived growth factor receptor binding, NAS | 1 genes |
| platelet-derived growth factor receptor binding, NR | 1 genes |
| potassium channel activity, NAS | 1 genes |
| potassium channel activity, NR | 1 genes |
| pyruvate carrier activity, TAS | 1 genes |
| profilin binding, NR | 1 genes |
| profilin binding, TAS | 1 genes |
| phospholipid binding, ISS | 1 genes |
| phosphatidylinositol binding, IDA | 1 genes |
| phosphatidylinositol binding, ISS | 1 genes |
| pheromone binding, IEA | 1 genes |
| proton-transporting ATP synthase, catalytic core (sensu Eukarya), TAS | 1 genes |
| peroxisomal membrane, IDA | 1 genes |
| peroxisomal membrane, ISS | 1 genes |
| peroxisomal membrane, NAS | 1 genes |
| peroxisomal matrix, TAS | 1 genes |
| polar microtubule, ISS | 1 genes |
| proteasome regulatory particle (sensu Eukarya), NAS | 1 genes |
| polysome, NR | 1 genes |
| plasma membrane, IC | 1 genes |
| plasma membrane, IEA | 1 genes |
| plasma membrane, IEP | 1 genes |
| phosphoinositide 3-kinase complex, NAS | 1 genes |
| phosphoinositide 3-kinase complex, NR | 1 genes |
| protein kinase CK2 complex, IEA | 1 genes |
| phosphorylase kinase complex, NAS | 1 genes |
| phosphorylase kinase complex, TAS | 1 genes |
| pyruvate dehydrogenase complex (sensu Eukarya), NAS | 1 genes |
| pyruvate dehydrogenase complex (sensu Eukarya), TAS | 1 genes |
| pentose-phosphate shunt, NAS | 1 genes |
| pentose-phosphate shunt, TAS | 1 genes |
| purine nucleotide metabolism, NAS | 1 genes |
| purine nucleotide biosynthesis, TAS | 1 genes |
| purine ribonucleoside salvage, TAS | 1 genes |
| pyrimidine base metabolism, IEA | 1 genes |
| pyrimidine nucleoside metabolism, TAS | 1 genes |
| pyrimidine nucleotide metabolism, NAS | 1 genes |
| postreplication repair, IDA | 1 genes |
| postreplication repair, NAS | 1 genes |
| protein biosynthesis, ISS | 1 genes |
| phenylalanyl-tRNA aminoacylation, TAS | 1 genes |
| prolyl-tRNA aminoacylation, NR | 1 genes |
| protein folding, IDA | 1 genes |
| protein thiol-disulfide exchange, TAS | 1 genes |
| protein amino acid phosphorylation, IC | 1 genes |
| protein amino acid dephosphorylation, IDA | 1 genes |
| protein amino acid acetylation, TAS | 1 genes |
| protein amino acid sulfation, IDA | 1 genes |
| protein amino acid methylation, IEA | 1 genes |
| protein amino acid methylation, ISS | 1 genes |
| protein amino acid demethylation, TAS | 1 genes |
| proteolysis and peptidolysis, IC | 1 genes |
| protein deglycosylation, NR | 1 genes |
| peptide metabolism, IEA | 1 genes |
| proline catabolism, TAS | 1 genes |
| polyamine biosynthesis, NAS | 1 genes |
| polyamine biosynthesis, TAS | 1 genes |
| protein targeting, IDA | 1 genes |
| protein-nucleus import, IDA | 1 genes |
| protein-nucleus import, NAS | 1 genes |
| protein-nucleus export, IDA | 1 genes |
| protein-nucleus export, NAS | 1 genes |
| protein-nucleus export, TAS | 1 genes |
| protein-membrane targeting, ISS | 1 genes |
| protein-membrane targeting, TAS | 1 genes |
| protein-lysosome targeting, IMP | 1 genes |
| phospholipid metabolism, IC | 1 genes |
| phospholipid metabolism, IEA | 1 genes |
| phospholipid metabolism, ISS | 1 genes |
| phosphatidylethanolamine biosynthesis, IDA | 1 genes |
| phosphatidylserine metabolism, TAS | 1 genes |
| phosphatidylinositol biosynthesis, IDA | 1 genes |
| platelet activating factor biosynthesis, ISS | 1 genes |
| platelet activating factor biosynthesis, NAS | 1 genes |
| prostaglandin metabolism, NAS | 1 genes |
| progesterone biosynthesis, TAS | 1 genes |
| phosphate metabolism, NR | 1 genes |
| polyphosphate metabolism, TAS | 1 genes |
| pyruvate transport, TAS | 1 genes |
| post-Golgi transport, ISS | 1 genes |
| pinocytosis, NAS | 1 genes |
| pinocytosis, NR | 1 genes |
| phagocytosis, recognition, IDA | 1 genes |
| phagocytosis, engulfment, IGI | 1 genes |
| phagocytosis, engulfment, NR | 1 genes |
| programmed cell death, virus-infected cells, NR | 1 genes |
| programmed cell death, transformed cells, NR | 1 genes |
| plasma membrane organization and biogenesis, TAS | 1 genes |
| peroxisome organization and biogenesis, IDA | 1 genes |
| peroxisome organization and biogenesis, NAS | 1 genes |
| phospholipase C activation, IDA | 1 genes |
| phospholipase C activation, ISS | 1 genes |
| phospholipase C activation, NAS | 1 genes |
| protein kinase C activation, IDA | 1 genes |
| protein kinase C activation, ISS | 1 genes |
| penetration of zona pellucida, ISS | 1 genes |
| posterior compartment specification, NR | 1 genes |
| posterior compartment specification, TAS | 1 genes |
| pattern specification, ISS | 1 genes |
| peripheral nervous system development, NAS | 1 genes |
| peripheral nervous system development, NR | 1 genes |
| posterior midgut development, TAS | 1 genes |
| primary sex determination, TAS | 1 genes |
| pregnancy, IEA | 1 genes |
| parturition, NAS | 1 genes |
| parturition, NR | 1 genes |
| physiological process, NR | 1 genes |
| protein C-terminus binding, IDA | 1 genes |
| protein localization, IC | 1 genes |
| protein localization, IMP | 1 genes |
| protein localization, ISS | 1 genes |
| protein localization, NAS | 1 genes |
| protein-methionine-S-oxide reductase activity, TAS | 1 genes |
| prostaglandin-I synthase activity, TAS | 1 genes |
| pancreatic elastase I activity, IEA | 1 genes |
| pancreatic elastase I activity, NAS | 1 genes |
| pancreatic elastase activity, TAS | 1 genes |
| protein tyrosine/serine/threonine phosphatase activity, NAS | 1 genes |
| poly(A) binding, IDA | 1 genes |
| protein phosphatase 1 binding, NAS | 1 genes |
| protein phosphatase 1 binding, TAS | 1 genes |
| positive transcription elongation factor activity, IEA | 1 genes |
| protein tyrosine phosphatase activator activity, IDA | 1 genes |
| protein tyrosine phosphatase activator activity, TAS | 1 genes |
| poly-pyrimidine tract binding, TAS | 1 genes |
| phosphatidate phosphatase activity, IDA | 1 genes |
| phosphatidate phosphatase activity, IEA | 1 genes |
| peptidase activity, IDA | 1 genes |
| peptidase activity, NR | 1 genes |
| pre-mRNA splicing factor activity, ISS | 1 genes |
| pre-mRNA splicing factor activity, NR | 1 genes |
| pyrimidine-specific mismatch base pair DNA N-glycosylase activity, TAS | 1 genes |
| poly(U) binding, TAS | 1 genes |
| protein methyltransferase activity, IEA | 1 genes |
| positive regulation of cell proliferation, ISS | 1 genes |
| positive regulation of cell proliferation, NAS | 1 genes |
| protein prenyltransferase activity, IEA | 1 genes |
| protein carrier activity, ISS | 1 genes |
| protein carrier activity, NR | 1 genes |
| pattern recognition receptor activity, IDA | 1 genes |
| pattern recognition receptor activity, ISS | 1 genes |
| protein kinase C inhibitor activity, ISS | 1 genes |
| protein kinase C inhibitor activity, NR | 1 genes |
| protein kinase C inhibitor activity, TAS | 1 genes |
| phosphatidylethanolamine binding, TAS | 1 genes |
| phosphofructokinase activity, IEA | 1 genes |
| palmitoyl-(protein) hydrolase activity, NAS | 1 genes |
| pyridoxal kinase activity, TAS | 1 genes |
| prenyl-dependent CAAX protease activity, TAS | 1 genes |
| protoheme IX farnesyltransferase activity, IEA | 1 genes |
| phosphatidylinositol transporter activity, NR | 1 genes |
| peptide receptor activity, G-protein coupled, NAS | 1 genes |
| purine-specific oxidized base lesion DNA N-glycosylase activity, IEA | 1 genes |
| purine-specific oxidized base lesion DNA N-glycosylase activity, TAS | 1 genes |
| proteasome activator activity, NR | 1 genes |
| proteasome inhibitor activity, NAS | 1 genes |
| plus-end-directed microtubule motor activity, TAS | 1 genes |
| protein phosphatase type 1 regulator activity, TAS | 1 genes |
| protein phosphatase type 2A regulator activity, IDA | 1 genes |
| protein kinase CK2 regulator activity, IEA | 1 genes |
| phosphorylase kinase regulator activity, TAS | 1 genes |
| pyridoxine biosynthesis, IEA | 1 genes |
| pyridoxine biosynthesis, NAS | 1 genes |
| phospholipid biosynthesis, NAS | 1 genes |
| phosphohistidine phosphatase activity, NAS | 1 genes |
| phosphohistidine phosphatase activity, TAS | 1 genes |
| polyphosphate kinase activity, TAS | 1 genes |
| pentose-phosphate shunt, oxidative branch, TAS | 1 genes |
| pentose-phosphate shunt, non-oxidative branch, NAS | 1 genes |
| purine ribonucleotide biosynthesis, IEA | 1 genes |
| pyrimidine deoxyribonucleotide catabolism, TAS | 1 genes |
| peptidoglycan biosynthesis, IEA | 1 genes |
| protein secretion, IEP | 1 genes |
| protein secretion, NR | 1 genes |
| phosphoribosylaminoimidazole carboxylase complex, IEA | 1 genes |
| phospholipid catabolism, IDA | 1 genes |
| putrescine biosynthesis, IEA | 1 genes |
| plasmodesma, TAS | 1 genes |
| post-embryonic development, NAS | 1 genes |
| positive regulation of signal transduction, NAS | 1 genes |
| protein transport, TAS | 1 genes |
| protein disulfide oxidoreductase activity, IDA | 1 genes |
| protein disulfide oxidoreductase activity, IEA | 1 genes |
| protein disulfide oxidoreductase activity, NAS | 1 genes |
| phosphate transporter activity, IEA | 1 genes |
| purine nucleoside transporter activity, TAS | 1 genes |
| purine nucleotide transporter activity, TAS | 1 genes |
| protein channel activity, ISS | 1 genes |
| protein channel activity, TAS | 1 genes |
| phosphate carrier activity, TAS | 1 genes |
| potassium:chloride symporter activity, ISS | 1 genes |
| potassium:chloride symporter activity, TAS | 1 genes |
| potassium:hydrogen antiporter activity, IDA | 1 genes |
| peptide antigen transporter activity, ISS | 1 genes |
| peptide antigen transporter activity, NAS | 1 genes |
| peptide antigen transporter activity, TAS | 1 genes |
| protein translocase activity, NAS | 1 genes |
| potassium channel regulator activity, NAS | 1 genes |
| peptide transport, ISS | 1 genes |
| peptide transport, NAS | 1 genes |
| purine nucleoside transport, TAS | 1 genes |
| peroxisomal long-chain fatty acid import, TAS | 1 genes |
| peroxisomal membrane transport, NAS | 1 genes |
| proton transport, ISS | 1 genes |
| peptidoglycan receptor activity, TAS | 1 genes |
| protein-arginine N-methyltransferase activity, NAS | 1 genes |
| phosphatidylinositol 3-kinase activity, NR | 1 genes |
| phosphorylation, IDA | 1 genes |
| phosphorylation, ISS | 1 genes |
| phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity, TAS | 1 genes |
| protein processing, ISS | 1 genes |
| protein processing, TAS | 1 genes |
| peptide hormone processing, IDA | 1 genes |
| peptide hormone processing, ISS | 1 genes |
| protein autoprocessing, NAS | 1 genes |
| peroxisome matrix protein import, IDA | 1 genes |
| peroxisome receptor docking, IEA | 1 genes |
| protein ubiquitination, IDA | 1 genes |
| protein ubiquitination, IMP | 1 genes |
| protein arginylation, NAS | 1 genes |
| PML body, IDA | 1 genes |
| phosphotransferase activity, phosphate group as acceptor, IEA | 1 genes |
| prolyl aminopeptidase activity, NAS | 1 genes |
| pyroglutamyl-peptidase II activity, IEA | 1 genes |
| protein sumoylation, ISS | 1 genes |
| procollagen C-endopeptidase activity, IEA | 1 genes |
| procollagen N-endopeptidase activity, IEA | 1 genes |
| purine nucleotide binding, NAS | 1 genes |
| phospholipid scrambling, TAS | 1 genes |
| phospholipid scramblase activity, TAS | 1 genes |
| pantetheinase activity, NAS | 1 genes |
| peptidyl-diphthamide biosynthesis from peptidyl-histidine, IEA | 1 genes |
| peptidyl-glutamic acid carboxylation, IEA | 1 genes |
| peptidyl-serine phosphorylation, ISS | 1 genes |
| peptide cross-linking, NAS | 1 genes |
| protein amino acid polyamination, NAS | 1 genes |
| protein amino acid prenylation, IEA | 1 genes |
| protein amino acid esterification, NAS | 1 genes |
| phosphatase regulator activity, NAS | 1 genes |
| phosphatase activator activity, IEA | 1 genes |
| phosphatase activator activity, TAS | 1 genes |
| phosphatase inhibitor activity, ISS | 1 genes |
| perception of pain, TAS | 1 genes |
| protein metabolism, IDA | 1 genes |
| pyrimidine base biosynthesis, IEA | 1 genes |
| protein kinase binding, IDA | 1 genes |
| protein kinase binding, TAS | 1 genes |
| protein phosphatase binding, NAS | 1 genes |
| protein domain specific binding, IDA | 1 genes |
| protein domain specific binding, IPI | 1 genes |
| pancreatic juice secretion, IDA | 1 genes |
| pancreatic juice secretion, NAS | 1 genes |
| protein xylosyltransferase activity, NAS | 1 genes |
| protein catabolism, NAS | 1 genes |
| PDZ domain binding, IDA | 1 genes |
| PDZ domain binding, NAS | 1 genes |
| proteoglycan biosynthesis, IDA | 1 genes |
| proteoglycan biosynthesis, NAS | 1 genes |
| pyridoxal phosphate binding, IEA | 1 genes |
| periplasmic space (sensu Gram-negative Bacteria), IEA | 1 genes |
| protein kinase activator activity, TAS | 1 genes |
| poly-N-acetyllactosamine metabolism, NAS | 1 genes |
| poly-N-acetyllactosamine biosynthesis, NAS | 1 genes |
| prenylated protein catabolism, NAS | 1 genes |
| prenylcysteine metabolism, NAS | 1 genes |
| positive regulation of cell migration, IDA | 1 genes |
| pre-mRNA cleavage factor activity, NAS | 1 genes |
| phosphoinositide metabolism, TAS | 1 genes |
| protease inhibitor activity, IEA | 1 genes |
| protease inhibitor activity, ISS | 1 genes |
| protease inhibitor activity, NAS | 1 genes |
| plasmin inhibitor activity, TAS | 1 genes |
| phagocytic vesicle membrane, IDA | 1 genes |
| phagocytic vesicle membrane, ISS | 1 genes |
| protein binding, bridging, IDA | 1 genes |
| protein binding, bridging, ISS | 1 genes |
| prostate gland development, NAS | 1 genes |
| positive regulation of dendritic cell activation, NAS | 1 genes |
| paranodal junction formation, ISS | 1 genes |
| phosphatidylinositol-4-phosphate 3-kinase activity, IEA | 1 genes |
| phosphatidylinositol-4-phosphate 3-kinase activity, NAS | 1 genes |
| positive regulation of activated T-cell proliferation, IDA | 1 genes |
| positive regulation of activated T-cell proliferation, TAS | 1 genes |
| phosphate binding, ISS | 1 genes |
| progesterone metabolism, IDA | 1 genes |
| positive regulation of tyrosine phosphorylation of Stat3 protein, IEP | 1 genes |
| positive regulation of tyrosine phosphorylation of Stat3 protein, TAS | 1 genes |
| positive regulation of tyrosine phosphorylation of Stat5 protein, IEP | 1 genes |
| positive regulation of tumor necrosis factor-alpha biosynthesis, IDA | 1 genes |
| positive regulation of tumor necrosis factor-alpha biosynthesis, ISS | 1 genes |
| peptide deformylase activity, IEA | 1 genes |
| peptide antigen binding, ISS | 1 genes |
| peptide antigen binding, NAS | 1 genes |
| peptide antigen binding, TAS | 1 genes |
| presynaptic membrane, IDA | 1 genes |
| protein ubiquitination during ubiquitin-dependent protein catabolism, IDA | 1 genes |
| protein ubiquitination during ubiquitin-dependent protein catabolism, TAS | 1 genes |
| protein self binding, ISS | 1 genes |
| protein homodimerization activity, IDA | 1 genes |
| protein homooligomerization activity, IDA | 1 genes |
| protein homooligomerization activity, ISS | 1 genes |
| protein homooligomerization activity, TAS | 1 genes |
| platelet dense granule, IDA | 1 genes |
| peroxisome proliferator activated receptor binding, IPI | 1 genes |
| positive regulation of tumor necrosis factor-beta biosynthesis, NAS | 1 genes |
| positive regulation of apoptosis, IDA | 1 genes |
| positive regulation of apoptosis, IEA | 1 genes |
| positive regulation of apoptosis, IMP | 1 genes |
| positive regulation of programmed cell death, NAS | 1 genes |
| positive thymic T-cell selection, ISS | 1 genes |
| positive regulation of viral genome replication, NAS | 1 genes |
| positive regulation of interferon-gamma biosynthesis, IDA | 1 genes |
| positive regulation of interferon-gamma biosynthesis, ISS | 1 genes |
| positive regulation of interferon-gamma biosynthesis, TAS | 1 genes |
| positive regulation of interleukin-10 biosynthesis, IDA | 1 genes |
| positive regulation of interleukin-10 biosynthesis, ISS | 1 genes |
| positive regulation of interleukin-12 biosynthesis, ISS | 1 genes |
| positive regulation of interleukin-12 biosynthesis, NAS | 1 genes |
| positive regulation of interleukin-2 biosynthesis, IDA | 1 genes |
| positive regulation of interleukin-2 biosynthesis, ISS | 1 genes |
| positive regulation of innate immune response, NAS | 1 genes |
| postsynaptic membrane, ISS | 1 genes |
| postsynaptic membrane, NAS | 1 genes |
| pyruvate dehydrogenase complex, IEA | 1 genes |
| positive regulation of MHC class II biosynthesis, IEP | 1 genes |
| positive regulation of interferon-beta biosynthesis, IMP | 1 genes |
| positive regulation of interleukin-1 biosynthesis, ISS | 1 genes |
| positive regulation of interleukin-13 biosynthesis, IDA | 1 genes |
| positive regulation of interleukin-4 biosynthesis, IDA | 1 genes |
| positive regulation of interleukin-4 biosynthesis, ISS | 1 genes |
| positive regulation of interleukin-4 biosynthesis, NAS | 1 genes |
| positive regulation of granulocyte macrophage colony-stimulating factor biosynthesis, NAS | 1 genes |
| positive regulation of nitric oxide biosynthesis, ISS | 1 genes |
| photoreceptor maintenance, ISS | 1 genes |
| photoreceptor maintenance, TAS | 1 genes |
| positive regulation of cholesterol biosynthesis, NAS | 1 genes |
| positive regulation of B-cell differentiation, NAS | 1 genes |
| positive regulation of T-cell differentiation, ISS | 1 genes |
| positive regulation of cytotoxic T-cell differentiation, ISS | 1 genes |
| positive regulation of cell differentiation, NAS | 1 genes |
| positive regulation of epidermal cell differentiation, TAS | 1 genes |
| positive regulation of keratinocyte differentiation, TAS | 1 genes |
| positive regulation of T-helper 1 cell differentiation, ISS | 1 genes |
| positive regulation of T-helper 1 cell differentiation, NAS | 1 genes |
| positive regulation of T-helper 2 cell differentiation, NAS | 1 genes |
| positive regulation of monocyte differentiation, IEP | 1 genes |
| positive regulation of myoblast differentiation, IDA | 1 genes |
| positive regulation of neuron differentiation, ISS | 1 genes |
| positive regulation of neuron differentiation, NAS | 1 genes |
| positive regulation of low-density lipoprotein receptor biosynthesis, NAS | 1 genes |
| positive regulation of gluconeogenesis, IDA | 1 genes |
| positive regulation of protein biosynthesis, NAS | 1 genes |
| positive regulation of protein catabolism, IDA | 1 genes |
| positive regulation of DNA repair, NAS | 1 genes |
| positive regulation of anti-apoptosis, IDA | 1 genes |
| positive regulation of anti-apoptosis, TAS | 1 genes |
| positive regulation of cell adhesion, NAS | 1 genes |
| positive regulation of endocytosis, NAS | 1 genes |
| positive regulation of meiosis, IMP | 1 genes |
| positive regulation of mitosis, NAS | 1 genes |
| positive regulation of mitotic metaphase/anaphase transition, NAS | 1 genes |
| positive regulation of transcription, DNA-dependent, IMP | 1 genes |
| positive regulation of transcription, DNA-dependent, TAS | 1 genes |
| positive regulation of vasodilation, NAS | 1 genes |
| positive regulation of DNA recombination, NAS | 1 genes |
| positive regulation of complement activation, ISS | 1 genes |
| positive regulation of transcription, IMP | 1 genes |
| positive regulation of transcription, TAS | 1 genes |
| positive regulation of transcription from Pol II promoter, ISS | 1 genes |
| positive regulation of transcription from Pol II promoter, TAS | 1 genes |
| positive regulation of smooth muscle contraction, IDA | 1 genes |
| positive regulation of glucose import, ISS | 1 genes |
| positive regulation of glucose import, NAS | 1 genes |
| positive regulation of JNK cascade, IDA | 1 genes |
| positive regulation of JNK cascade, ISS | 1 genes |
| polynucleotide 3'-phosphatase activity, IDA | 1 genes |
| phosphatidylinositol metabolism, NAS | 1 genes |
| passive viral induction of host immune response, ISS | 1 genes |
| phospholipid dephosphorylation, TAS | 1 genes |
| positive regulation of follicle-stimulating hormone secretion, IPI | 1 genes |
| peptide-O-fucosyltransferase activity, IEA | 1 genes |
| peptide-O-fucosyltransferase activity, TAS | 1 genes |
| phosphatidylinositol 3-kinase regulator activity, ISS | 1 genes |
| phosphatidylinositol 3-kinase regulator activity, TAS | 1 genes |
| protein heterodimerization activity, IDA | 1 genes |
| protein dimerization activity, IPI | 1 genes |
| protein dimerization activity, ISS | 1 genes |
| protein dimerization activity, NAS | 1 genes |
| prostaglandin-F synthase activity, IEA | 1 genes |
| phospholipid-hydroperoxide glutathione peroxidase activity, IEA | 1 genes |
| phosphatidylcholine-retinol O-acyltransferase activity, IEA | 1 genes |
| positive regulation of eye pigmentation, TAS | 1 genes |
| positive regulation of cuticle pigmentation, TAS | 1 genes |
| positive regulation of fibroblast proliferation, NAS | 1 genes |
| plasma membrane to endosome transport, NAS | 1 genes |
| phytanoyl-CoA dioxygenase activity, IEA | 1 genes |
| positive regulation of receptor mediated endocytosis, NAS | 1 genes |
| phenylpyruvate tautomerase activity, IEA | 1 genes |
| prostaglandin-E synthase activity, IDA | 1 genes |
| prostaglandin-E synthase activity, IEA | 1 genes |
| prostaglandin-E2 9-reductase activity, IEA | 1 genes |
| positive regulation of urothelial cell proliferation, IDA | 1 genes |
| proteoglycan sulfotransferase activity, NAS | 1 genes |
| positive regulation of protein secretion, TAS | 1 genes |
| positive regulation of interleukin-1 secretion, NAS | 1 genes |
| positive regulation of interleukin-1 beta secretion, NAS | 1 genes |
| positive regulation of interleukin-1 beta biosynthesis, IDA | 1 genes |
| positive regulation of inflammatory response, IEP | 1 genes |
| positive regulation of inflammatory response, NAS | 1 genes |
| positive regulation of peptidyl-tyrosine phosphorylation, IDA | 1 genes |
| positive regulation of fractalkine biosynthesis, IDA | 1 genes |
| positive regulation of phagocytosis, TAS | 1 genes |
| positive regulation of neurogenesis, IDA | 1 genes |
| protein stabilization, IEP | 1 genes |
| protein stabilization, IPI | 1 genes |
| peptide antigen stabilization, ISS | 1 genes |
| protein kinase A binding, IDA | 1 genes |
| protein kinase A binding, ISS | 1 genes |
| protein kinase A binding, NR | 1 genes |
AS3D Human
