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Human Gene Lists K
KRAB, KRAB box. The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally enco
341 genes
kinase activity, IEA
141 genes
Kelch, Kelch motif. The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown for one member that it is related to Galactose Oxidase for which a structure has been solved. The kelch
60 genes
K_tetra, K+ channel tetramerisation domain. The N-terminal, cytoplasmic tetramerisation domain (T1) of voltage-gated K+ channels encodes molecular determinants for subfamily-specific assembly of alpha-subunits into functional tetrameric channe
53 genes
Kinesin, Kinesin motor domain
50 genes
KH, KH domain. KH motifs can bind RNA in vitro. Autoantibodies to Nova, a KH domain protein, cause paraneoplastic opsoclonus ataxia
30 genes
Kazal, Kazal-type serine protease inhibitor domain. Usually indicative of serine protease inhibitors. However, kazal-like domains are also seen in the extracellular part of agrins, which are not known to be protease inhibitors. Kazal domains o
22 genes
Kdo, Lipopolysaccharide kinase (Kdo/WaaP) family. These lipopolysaccharide kinases are related to protein kinases pfam00069. This family includes waaP (rfaP) gene product is required for the addition of phosphate to O-4 of the first heptose re
18 genes
Kunitz_BPTI, Kunitz/Bovine pancreatic trypsin inhibitor domain. Indicative of a protease inhibitor, usually a serine protease inhibitor. Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensivel
17 genes
Kringle, Kringle domain. Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta
17 genes
keratin filament, IEA
17 genes
kinetochore, TAS
13 genes
Keratin, Keratin. This family represents avian keratin proteins, found in feathers, scale and claw
9 genes
Krr1, Krr1 family. The yeast member of this family is found to be required for 40S ribosome biogenesis in the nucleolus
9 genes
KE2, KE2 family protein. The function of members of this family is unknown, although they have been suggested to contain a DNA binding leucine zipper motif
8 genes
Kinesin-related, Kinesin-related. This family represents a region within kinesin-related proteins from higher plants. Many family members also contain the pfam00225 domain. Kinesins are ATP-driven microtubule motor proteins that produce direct
8 genes
kinesin complex, TAS
8 genes
kainate selective glutamate receptor activity, TAS
6 genes
ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain. The structure of beta-ketoacyl synthase is similar to that of the thiolase family (Pfam::PF00108) and also chalcone sythase. The active site of beta-ketoacyl synthase is located between
5 genes
KCNQ_channel, KCNQ voltage-gated potassium channel. This family matches to the C-terminal tail of KCNQ type potassium channels
5 genes
KA1, Kinase associated domain 1
4 genes
Ku, Ku70/Ku80 beta-barrel domain. The Ku heterodimer (composed of Ku70 and Ku80) contributes to genomic integrity through its ability to bind DNA double-strand breaks and facilitate repair by the non-homologous end-joining pathway. This is the
4 genes
Ku_N, Ku70/Ku80 N-terminal alpha/beta domain. The Ku heterodimer (composed of Ku70 and Ku80) contributes to genomic integrity through its ability to bind DNA double-strand breaks and facilitate repair by the non-homologous end-joining pathway.
4 genes
KAP, Kinesin-associated protein (KAP). This family consists of several eukaryotic kinesin-associated (KAP) proteins. Kinesins are intracellular multimeric transport motor proteins that move cellular cargo on microtubule tracks. It has been sho
4 genes
kinesin complex, IEA
4 genes
Keratin_B2, Keratin, high sulfur B2 protein. High sulfur proteins are cysteine-rich proteins synthesised during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family
3 genes
Ku_C, Ku70/Ku80 C-terminal arm. The Ku heterodimer (composed of Ku70 and Ku80) contributes to genomic integrity through its ability to bind DNA double-strand breaks and facilitate repair by the non-homologous end-joining pathway. This is the C
3 genes
Keratin_matx, Keratin, high-sulphur matrix protein. Family of Keratin, high-sulfur matrix proteins. The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other prote
3 genes
keratinocyte differentiation, NAS
3 genes
KIX, KIX domain. CBP and P300 bind to the CREB via a domain known as KIX. The KIX domain of CBP also binds to transactivation domains of other nuclear factors including Myb and Jun
2 genes
Ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain. The structure of beta-ketoacyl synthase is similar to that of the thiolase family (Pfam::PF00108) and also chalcone sythase. The active site of beta-ketoacyl synthase is located betwe
2 genes
Kv2channel, Kv2 voltage-gated K+ channel
2 genes
KCl_Cotrans_1, K-Cl Co-transporter type 1 (KCC1)
2 genes
KDEL sequence binding, TAS
2 genes
kinetochore microtubule, IDA
2 genes
kynurenine-oxoglutarate transaminase activity, IEA
2 genes
kinase inhibitor activity, ISS
2 genes
kinesin binding, ISS
2 genes
KOW, KOW motif. The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG
1 genes
kinetochore, IDA
1 genes
kinetochore, NAS
1 genes
ketohexokinase activity, TAS
1 genes
kynurenine 3-monooxygenase activity, TAS
1 genes
kappa-opioid receptor activity, TAS
1 genes
kainate selective glutamate receptor activity, IDA
1 genes
kainate selective glutamate receptor activity, NR
1 genes
kinase activity, NAS
1 genes
kinesin II complex, ISS
1 genes
kinase inhibitor activity, IDA
1 genes
kinase inhibitor activity, NAS
1 genes
kinesin binding, IEA
1 genes
kinesin binding, IPI
1 genes
kinesin binding, TAS
1 genes
kinase binding, IPI
1 genes
kinase binding, ISS
1 genes
keratinocyte differentiation, IEA
1 genes
keratinocyte differentiation, ISS
1 genes
kynureninase activity, IEA
1 genes
AS3D: Alternative Splicing Structural Genomics Projects
CARB/UMBI