| DNA binding, IEA | 633 genes |
| development, IEA | 214 genes |
| development, TAS | 141 genes |
| DUF164, Uncharacterized ACR, COG1579 | 126 genes |
| Daxx, Daxx Family. The Daxx protein (also known as the Fas-binding protein) is thought to play a role in apoptosis, but precise role played by Daxx remians to be determined | 112 genes |
| DNA binding, TAS | 102 genes |
| DUF1421, Protein of unknown function (DUF1421). This family represents a conserved region approximately 350 residues long within a number of plant proteins of unknown function | 98 genes |
| DNA_pol_V, DNA polymerase V. This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localised exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units | 95 genes |
| DUF869, Plant protein of unknown function (DUF869). This family consists of a number of sequences found in Arabidopsis thaliana, Oryza sativa and Lycopersicon esculentum (Tomato). The function of this family is unknown | 88 genes |
| DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transc | 79 genes |
| DNA binding, NAS | 69 genes |
| DUF874, Helicobacter pylori protein of unknown function (DUF874). This family consists of several hypothetical proteins specific to Helicobacter pylori. The function of this family is unknown | 60 genes |
| Drf_FH1, Formin Homology Region 1. This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues | 58 genes |
| DAG_PE-bind, Phorbol esters/diacylglycerol binding domain (C1 domain). This domain is also known as the Protein kinase C conserved region 1 (C1) domain | 55 genes |
| development, NAS | 49 genes |
| DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens are conf | 48 genes |
| DNA repair, IEA | 47 genes |
| DSPc, Dual specificity phosphatase, catalytic domain. Ser/Thr and Tyr protein phosphatases. The enzyme's tertiary fold is highly similar to that of tyrosine-specific phosphatases, except for a "recognition" region | 46 genes |
| DUF390, Protein of unknown function (DUF390). This family of long proteins are currently only found in the rice genome. They have no known function. However they may be some kind of transposable element | 45 genes |
| DUF605, Protein of unknown function, DUF605. This family includes several uncharacterised eukaryotic proteins | 43 genes |
| DNA repair, TAS | 43 genes |
| DUF827, Plant protein of unknown function (DUF827). This family consists of several plant proteins of unknown function. Several sequences in this family are described as being "myosin heavy chain-like" | 40 genes |
| DNA replication, IEA | 39 genes |
| DUF1210, Protein of unknown function (DUF1210). This family represents a conserved region within plant proline-rich proteins | 35 genes |
| defense response, TAS | 33 genes |
| digestion, TAS | 33 genes |
| Duffy_binding, Plasmodium Duffy binding protein. This family contains several Plasmodium Duffy binding proteins.Plasmodium vivax and Plasmodium knowlesi merozoites invade human erythrocytes that express Duffy blood group surface determinants. | 32 genes |
| diacylglycerol binding, IEA | 31 genes |
| Death, Death domain | 29 genes |
| defense response, IEA | 29 genes |
| DUF566, Family of unknown function (DUF566). Family of related proteins that is plant specific | 28 genes |
| DEC-1_N, DEC-1 protein, N terminal region. The defective chorion-1 gene (dec-1) in Drosophila encodes follicle cell proteins necessary for proper eggshell assembly. Multiple products of the dec-1 gene are formed by alternative RNA splicing and | 28 genes |
| DNA replication, TAS | 28 genes |
| DUF1167, Protein of unknown function (DUF1167). This family consists of several uncharacterised mammalian proteins of unknown function | 26 genes |
| DUF1517, Protein of unknown function (DUF1517). This family consists of several hypothetical glycine rich plant and bacterial proteins of around 300 residues in length. The function of this family is unknown | 26 genes |
| DUF729, Protein of unknown function (DUF729). This family consists of several uncharacterised eukaryotic proteins of unknown function | 23 genes |
| Disintegrin, Disintegrin | 22 genes |
| DUF1220, Repeat of unknown function (DUF1220). This family consists of several mammalian specific repeats of around 65 residues in length and is found in multiple copies in several human proteins. The function of this family is unknown | 22 genes |
| DUF572, Family of unknown function (DUF572). Family of eukaryotic proteins with undetermined function | 20 genes |
| DEP, Domain found in Dishevelled, Egl-10, and Pleckstrin. Domain of unknown function present in signaling proteins that contain pfam00169, rasGEF, rhoGEF, rhoGAP, pfam00615, pfam00595 domains | 19 genes |
| DUF1423, Protein of unknown function (DUF1423). This family represents a conserved region approximately 500 residues long within a number of Arabidopsis thaliana proteins of unknown function | 19 genes |
| dsrm, Double-stranded RNA binding motif. Sequences gathered for seed by HMM_iterative_training Putative motif shared by proteins that bind to dsRNA. At least some DSRM proteins seem to bind to specific RNA targets. Exemplified by Staufen, whic | 17 genes |
| DUF1509, Protein of unknown function (DUF1509). This family consists of several uncharacterised viral proteins from the Marek's disease-like viruses. Members of this family are typically around 400 residues in length. The function of this fami | 17 genes |
| double-stranded RNA binding, IEA | 17 genes |
| development, NR | 17 genes |
| DENN, DENN (AEX-3) domain. DENN (after differentially expressed in neoplastic vs normal cells) is a domain which occurs in several proteins involved in Rab- mediated processes or regulation of MAPK signalling pathways | 16 genes |
| DUF812, Protein of unknown function (DUF812). This family consists of several eukaryotic proteins of unknown function | 16 genes |
| damaged DNA binding, IEA | 16 genes |
| DNA-directed RNA polymerase activity, IEA | 16 genes |
| DAGK_cat, Diacylglycerol kinase catalytic domain (presumed). Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologues | 15 genes |
| Dynein_heavy, Dynein heavy chain. This family represents the C-terminal region of dynein heavy chain. The chain also contains ATPase activity and microtubule binding ability and acts as a motor for the movement of organelles and vesicles along | 15 genes |
| dDENN, dDENN domain. This region is always found associated with pfam02141. It is predicted to form a globular domain. This domain is predicted to be completely alpha helical. Although not statistically supported it has been suggested that thi | 15 genes |
| DMP1, Dentin matrix protein 1 (DMP1). This family consists of several mammalian dentin matrix protein 1 (DMP1) sequences. The dentin matrix acidic phosphoprotein 1 (DMP1) gene has been mapped to human chromosome 4q21. DMP1 is a bone and teeth | 15 genes |
| damaged DNA binding, TAS | 15 genes |
| DNA-dependent ATPase activity, IEA | 15 genes |
| disulfide oxidoreductase activity, IEA | 15 genes |
| Dicty_REP, Dictyostelium (Slime Mold) REP protein. This family consists of REP proteins from Dictyostelium (Slime molds). REP protein is likely involved in transcription regulation and control of DNA replication, specifically amplification of | 14 genes |
| DNA recombination, TAS | 14 genes |
| DDE, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE s | 13 genes |
| DUF590, Protein of unknown function, DUF590. This family contains several uncharacterised eukaryotic proteins | 13 genes |
| double-stranded DNA binding, TAS | 13 genes |
| DNA metabolism, IEA | 13 genes |
| DNA replication, NAS | 13 genes |
| DAO, FAD dependent oxidoreductase. This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4 | 12 genes |
| DUF634, Protein of unknown function (DUF634). Mammalian protein of unknown function | 11 genes |
| DUF936, Plant protein of unknown function (DUF936). This family consists of several hypothetical proteins from Arabidopsis thaliana and Oryza sativa. The function of this family is unknown | 11 genes |
| Ded_cyto, Dedicator of cytokinesis. This family represents a conserved region approximately 200 residues long within a number of eukaryotic dedicator of cytokinesis proteins. These are potential guanine nucleotide exchange factors, which activ | 11 genes |
| DNA-directed RNA polymerase II, core complex, TAS | 11 genes |
| DNA recombination, IEA | 11 genes |
| dynein complex, IEA | 11 genes |
| defense response to fungi, IEA | 11 genes |
| DAGK_acc, Diacylglycerol kinase accessory domain (presumed). Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. This domain is assumed to be an accessory domain: its function is unknown | 10 genes |
| DLH, Dienelactone hydrolase family | 10 genes |
| DCX, Doublecortin | 10 genes |
| DNA binding, NR | 10 genes |
| DnaJ_C, DnaJ C terminal region. This family consists of the C terminal region form the DnaJ protein. Although the function of this region is unknown, it is always found associated with pfam00226 and pfam00684. DnaJ is a chaperone associated wi | 9 genes |
| Dala_Dala_ligas, D-ala D-ala ligase. This family contains D-alanine--D-alanine ligase enzymes EC:6.3.2.4 | 9 genes |
| DUF612, Protein of unknown function, DUF612. This family includes several uncharacterized proteins from Caenorhabditis elegans | 9 genes |
| Drf_FH3, Diaphanous FH3 Domain. This region is found in the Formin-like and and diaphanous proteins | 9 genes |
| Drf_GBD, Diaphanous GTPase-binding Domain. This domain is bound to by GTP-attached Rho proteins, leading to activation of the Drf protein | 9 genes |
| DNA-directed RNA polymerase activity, TAS | 9 genes |
| delayed rectifier potassium channel activity, TAS | 9 genes |
| DNA replication initiation, TAS | 9 genes |
| DAGAT, Diacylglycerol acyltransferase. The terminal step of triacylglycerol (TAG) formation is catalysed by the enzyme diacylglycerol acyltransferase (DAGAT) | 8 genes |
| DAG1, Dystroglycan (Dystrophin-associated glycoprotein 1). Dystroglycan is one of the dystrophin-associated glycoproteins, which is encoded by a 5.5 kb transcript in human. The protein product is cleaved into two non-covalently associated subu | 8 genes |
| DUF857, Domain of unknown function (DUF857). This family consists of several domains of unknown function which are commonly found in multiple copies in the pfam00246 family | 8 genes |
| DNA helicase activity, TAS | 8 genes |
| double-stranded RNA binding, TAS | 8 genes |
| diacylglycerol kinase activity, IEA | 8 genes |
| DNA metabolism, TAS | 8 genes |
| DNA-dependent DNA replication, TAS | 8 genes |
| defense response, NR | 8 genes |
| Dynamin_N, Dynamin family | 7 genes |
| DM, DM DNA binding domain. The DM domain is named after dsx and mab-3. dsx contains a single amino-terminal DM domain, whereas mab-3 contains two amino-terminal domains. The DM domain has a pattern of conserved zinc chelating residues C2H2C4. | 7 genes |
| DPPIV_N, Dipeptidyl peptidase IV (DPP IV) N-terminal region. This family is an alignment of the region to the N-terminal side of the active site | 7 genes |
| DED, Death effector domain | 7 genes |
| Dicty_CAR, Slime mold cyclic AMP receptor. This family consists of cyclic AMP receptor (CAR) proteins from slime molds. CAR proteins are responsible for controlling development in Dictyostelium discoideum | 7 genes |
| DUF1041, Domain of Unknown Function (DUF1041). This family consists of several eukaryotic domains of unknown function. Members of this family are often found in tandem repeats and co-occur with pfam00168, pfam00130 and pfam00169 domains | 7 genes |
| DUF1053, Domain of Unknown Function (DUF1053). This domain is found in Adenylate cyclases | 7 genes |
| DNA binding, ISS | 7 genes |
| DNA-directed DNA polymerase activity, IEA | 7 genes |
| diacylglycerol kinase activity, TAS | 7 genes |
| DNA topological change, IEA | 7 genes |
| DNA replication initiation, IEA | 7 genes |
| DNA repair, NAS | 7 genes |
| double-strand break repair, TAS | 7 genes |
| DNA packaging, TAS | 7 genes |
| dicarboxylic acid transport, IEA | 7 genes |
| defense response to bacteria, TAS | 7 genes |
| dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region | 6 genes |
| DIX, DIX domain. The DIX domain is present in Dishevelled and axin. This domain is involved in homo- and hetero-oligomerisation. It is involved in the homo- oligomerisation of mouse axin. The axin DIX domain also interacts with the dishevelled | 6 genes |
| Defensin_propep, Defensin propeptide | 6 genes |
| Dynamin_M, Dynamin central region. This region lies between the GTPase domain, see pfam00350, and the pleckstrin homology (PH) domain, see pfam00169 | 6 genes |
| Dynein_light, Dynein light chain type 1 | 6 genes |
| DIL, DIL domain. The DIL domain has no known function | 6 genes |
| DDHD, DDHD domain. The DDHD domain is 180 residues long and contains four conserved residues that may form a metal binding site. The domain is named after these four residues. This pattern of conservation of metal binding residues is often see | 6 genes |
| DAN, DAN domain. This domain contains 9 conserved cysteines and is extracellular. Therefore the cysteines may form disulphide bridges. This family of proteins has been termed the DAN family after the first member to be reported. This family in | 6 genes |
| DUF609, Protein of unknown function, DUF609. This family represents a conserved domain which is found in a number of eukaryotic proteins including CED-12, ELMO I and ELMO II. ELMO1 is a component of signalling pathways that regulate phagocytos | 6 genes |
| DUF618, Protein of unknown function, DUF618. This family represents a conserved region found in a number of uncharacterised eukaryotic proteins | 6 genes |
| DUF663, Protein of unknown function (DUF663). This family contains several uncharacterised eukaryotic proteins | 6 genes |
| DUF803, Protein of unknown function (DUF803). This family consists of several eukaryotic proteins of unknown function | 6 genes |
| DUF914, Eukaryotic protein of unknown function (DUF914). This family consists of several hypothetical proteins of unknown function. Some of the sequences in this family are annotated as being putative membrane proteins | 6 genes |
| DUF1014, Protein of unknown function (DUF1014). This family consists of several hypothetical eukaryotic proteins of unknown function | 6 genes |
| DEAD_2, DEAD_2. This represents a conserved region within a number of RAD3-like DNA-binding helicases that are seemingly ubiquitous - members include proteins of eukaryotic, bacterial and archaeal origin. RAD3 is involved in nucleotide excisio | 6 genes |
| DNA damage checkpoint, TAS | 6 genes |
| DNA repair, NR | 6 genes |
| DNA methylation, TAS | 6 genes |
| DNA damage response, signal transduction resulting in induction of apoptosis, TAS | 6 genes |
| Defensin_1, Mammalian defensin | 5 genes |
| DegT_DnrJ_EryC1, DegT/DnrJ/EryC1/StrS aminotransferase family. The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. T | 5 genes |
| Dus, Dihydrouridine synthase (Dus). Members of this family catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also in some archa | 5 genes |
| DNA_pol_B_exo, DNA polymerase family B, exonuclease domain. This domain has 3' to 5' exonuclease activity and adopts a ribonuclease H type fold | 5 genes |
| DUF298, Domain of unknown function (DUF298). Members of this family contain a basic helix-loop-helix leucine zipper motif | 5 genes |
| DUF580, Protein of unknown function, DUF580 | 5 genes |
| DFNA5, DFNA5 protein. The precise function of this protein is unknown. A deletion/insertion mutation is associated with an autosomal dominant non-syndromic hearing impairment form. In addition, this protein has also been found to contribute to | 5 genes |
| Dpy-30, Dpy-30 motif. This motif is found in a wide variety of domain contexts. It is found in the Dpy-30 proteins hence the motifs name. It is about 40 residues long and is probably formed of two alpha-helices. It may be a dimerisation motif | 5 genes |
| DUF745, Protein of unknown function (DUF745). This family consists of several uncharacterised Drosophila melanogaster proteins of unknown function | 5 genes |
| DUF758, Domain of unknown function (DUF758). Family of eukaryotic proteins with unknown function, which are induced by tumour necrosis factor | 5 genes |
| DUF887, Eukaryotic protein of unknown function (DUF887). This family consists of several conserved eukaryotic proteins of unknown function | 5 genes |
| DUF958, Domain of Unknown Function (DUF958) | 5 genes |
| DUF1042, Domain of Unknown Function (DUF1042) | 5 genes |
| DUF1172, Protein of unknown function (DUF1172). This family represents a conserved region of unknown function within NAC1 and a number of hypothetical proteins whose sequences bear resemblance to it. NAC1 is a constitutively-expressed POZ/BTB | 5 genes |
| DNA replication and chromosome cycle, TAS | 5 genes |
| DNA-directed RNA polymerase activity, NAS | 5 genes |
| dipeptidyl-peptidase IV activity, IEA | 5 genes |
| dopamine receptor activity, TAS | 5 genes |
| death receptor binding, TAS | 5 genes |
| DNA replication factor C complex, IEA | 5 genes |
| dopamine receptor signaling pathway, TAS | 5 genes |
| development, ISS | 5 genes |
| digestion, IEA | 5 genes |
| digestion, NR | 5 genes |
| DNA restriction, IEA | 5 genes |
| detection of pest, pathogen or parasite, TAS | 5 genes |
| dipeptidase activity, IEA | 5 genes |
| DNA_pol_B, DNA polymerase family B. This region of DNA polymerase B appears to consist of more than one structural domain, possibly including elongation, DNA-binding and dNTP binding activities | 4 genes |
| DNA_methylase, C-5 cytosine-specific DNA methylase | 4 genes |
| DNA_topoisoIV, DNA gyrase/topoisomerase IV, subunit A | 4 genes |
| DnaJ_CXXCXGXG, DnaJ central domain (4 repeats). The central cysteine-rich (CR) domain of DnaJ proteins contains four repeats of the motif CXXCXGXG where X is any amino acid. The isolated cysteine rich domain folds in zinc dependent fashion. Ea | 4 genes |
| DUF6, Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region | 4 genes |
| DNA_mis_repair, DNA mismatch repair protein, C-terminal domain. This family represents the C-terminal domain of the mutL/hexB/PMS1 family. This domain has a ribosomal S5 domain 2-like fold | 4 genes |
| DSL, Delta serrate ligand | 4 genes |
| dNK, Deoxynucleoside kinase. This family consists of various deoxynucleoside kinases cytidine EC:2.7.1.74, guanosine EC:2.7.1.113, adenosine EC:2.7.1.76 and thymidine kinase EC:2.7.1.21 (which also phosphorylates deoxyuridine and deoxycytosine | 4 genes |
| DDT, DDT domain. This domain is predicted to be a DNA binding domain. The DDT domain is named after (DNA binding homeobox and Different Transcription factors) | 4 genes |
| DIM1, Mitosis protein DIM1 | 4 genes |
| DUF258, Protein of unknown function, DUF258 | 4 genes |
| DnaB_C, DnaB-like helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA a | 4 genes |
| DUF343, Protein of unknown function (DUF343). This family of short proteins have no known function. The bacterial members are about 60-70 amino acids in length and the eukaryotic examples are about 120 amino acids in length. The C terminus con | 4 genes |
| Dickkopf_N, Dickkopf N-terminal cysteine-rich region. Dickkopf proteins are a class of Wnt antagonists. They possess two conserved cysteine-rich regions. This family represents the N-terminal one. The C-terminal region has been found to share | 4 genes |
| DUF625, Protein of unknown function (DUF625). Family of uncharacterised proteins | 4 genes |
| DUF636, Protein of unknown function (DUF636). This family of proteins has no known function, but several strongly conserved cysteine residues | 4 genes |
| DUF741, Protein of unknown function (DUF741). This family contains several uncharacterized human proteins. The function of this family is unknown, however, the family member FKSG56 is a hepatocellular carcinoma-associated antigen | 4 genes |
| DUF798, Protein of unknown function (DUF798). This family consists of several eukaryotic proteins of unknown function | 4 genes |
| DUF1055, Domain of Unknown Function (DUF1055). This region is found in Ubiquitin-specific proteases | 4 genes |
| DMAP_binding, DMAP1-binding Domain. This domain binds DMAP1, a transcriptional co-repressor | 4 genes |
| DUF1168, Protein of unknown function (DUF1168). This family consists of several hypothetical eukaryotic proteins of unknown function | 4 genes |
| DUF1193, Protein of unknown function (DUF1193). This family represents the C-terminus of several hypothetical eukaryotic proteins of unknown function. Family members contain two conserved motifs: DRHHYE and QCC, as well as a number of conserve | 4 genes |
| DUF1394, Protein of unknown function (DUF1394). This family consists of several hypothetical eukaryotic proteins of around 320 residues in length. The function of this family is unknown | 4 genes |
| DNA replication checkpoint, TAS | 4 genes |
| DNA binding, IDA | 4 genes |
| damaged DNA binding, NAS | 4 genes |
| DNA replication origin binding, TAS | 4 genes |
| dihydropyrimidinase activity, TAS | 4 genes |
| DNA replication factor A complex, TAS | 4 genes |
| DNA replication factor C complex, TAS | 4 genes |
| DNA-directed RNA polymerase II, core complex, NR | 4 genes |
| DNA unwinding, IEA | 4 genes |
| DNA methylation, IEA | 4 genes |
| DNA catabolism, IEA | 4 genes |
| DNA fragmentation, TAS | 4 genes |
| D-alanyl-D-alanine endopeptidase activity, IEA | 4 genes |
| detection of abiotic stimulus, TAS | 4 genes |
| dihydropyridine-sensitive calcium channel activity, TAS | 4 genes |
| dystrophin-associated glycoprotein complex, TAS | 4 genes |
| detection of bacteria, IDA | 4 genes |
| diacylglycerol binding, NAS | 4 genes |
| defense response to bacteria, NAS | 4 genes |
| defense response to Gram-positive bacteria, IDA | 4 genes |
| DNA_pol_A, DNA polymerase family A | 3 genes |
| DNA_ligase_A_M, ATP dependent DNA ligase domain. This domain belongs to a more diverse superfamily, including pfam01331 and pfam01653 | 3 genes |
| DUF21, Domain of unknown function DUF21. This transmembrane region has no known function. Many of the sequences in this family are annotated as hemolysins, however this is due to a similarity to a protein, which does not contain this domain. T | 3 genes |
| DJ-1_PfpI, DJ-1/PfpI family. The family includes the protease PfpI. This domain is also found in transcriptional regulators. This family appears to be distantly related to Glutamine amidotransferases pfam00117 | 3 genes |
| Dishevelled, Dishevelled specific domain. This domain is specific to the signaling protein dishevelled. The domain is found adjacent to the PDZ domain pfam00595, often in conjunction with DEP (pfam00610) and DIX (pfam00778) | 3 genes |
| DUF221, Domain of unknown function DUF221. This family consists of hypothetical transmembrane proteins none of which have any function, the aligned region is at 538 residues at maximum length | 3 genes |
| DUF229, Protein of unknown function (DUF229). Members of this family are uncharacterised. They are 500-1200 amino acids in length and share a long region conservation that probably corresponds to several domains | 3 genes |
| DUF270, Protein of unknown function, DUF270 | 3 genes |
| DOMON, DOMON domain. The DOMON (named after dopamine beta-monooxygenase N-terminal) domain is 110-125 residues long. It is predicted to form an all beta fold with 7-8 strands. The domain may mediate extracellular adhesive interactions | 3 genes |
| DMA, DMRTA motif. This region is found to the C-terminus of the pfam00751. DM-domain proteins with this motif are known as DMRTA proteins. The function of this region is unknown | 3 genes |
| DUF300, Domain of unknown function | 3 genes |
| DUF342, Protein of unknown function (DUF342). This family of bacterial proteins has no known function. The proteins are in the region of 500-600 amino acid residues in length | 3 genes |
| Dysbindin, Dysbindin (Dystrobrevin binding protein 1). Dysbindin is an evolutionary conserved 40-kDa coiled-coil-containing protein that binds to alpha- and beta-dystrobrevin in muscle and brain. Dystrophin and alpha-dystrobrevin are co-immuno | 3 genes |
| DER1, Der1-like family. The endoplasmic reticulum (ER) of the yeast Saccharomyces cerevisiae contains of proteolytic system able to selectively degrade misfolded lumenal secretory proteins. For examination of the components involved in this de | 3 genes |
| DNA_ligase_A_N, DNA ligase N terminus. This region is found in many but not all ATP-dependent DNA ligase enzymes (EC:6.5.1.1). It is thought to be involved in DNA binding and in catalysis. In human DNA ligase I, and in Saccharomyces cerevisiae | 3 genes |
| DNA_ligase_A_C, ATP dependent DNA ligase C terminal region. This region is found in many but not all ATP-dependent DNA ligase enzymes (EC:6.5.1.1). It is thought to constitute part of the catalytic core of ATP dependent DNA ligase | 3 genes |
| DUF614, Protein of unknown function, DUF614. This family includes a number of uncharacterised eukaryotic proteins | 3 genes |
| DUF716, Family of unknown function (DUF716). This family is equally distributed in both metazoa and plants. Annotation associated with some members suggest that it may be involved in response to viral attack in plants. However, no clear functi | 3 genes |
| DUF652, Protein of unknown function, DUF652. This family includes several uncharacterized eukaryotic proteins | 3 genes |
| DUF667, Protein of unknown function (DUF667). This family of proteins are highly conserved in eukaryotes. Some proteins in the family are annotated as transcription factors. However, there is currently no support for this in the literature | 3 genes |
| DUF726, Protein of unknown function (DUF726). This family consists of several uncharacterised eukaryotic proteins | 3 genes |
| DARPP-32, Protein phosphatase inhibitor 1/DARPP-32. This family consists of several mammalian protein phosphatase inhibitor 1 (IPP-1) and dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32) proteins. Protein phosphatase inhibitor-1 | 3 genes |
| DUF755, Domain of unknown function (DUF755). This family is predominated by ORFs from Circoviridae. The function of this family remains to be determined | 3 genes |
| DREPP, DREPP plasma membrane polypeptide. This family contains several plant plasma membrane proteins termed DREPPs as they are developmentally regulated plasma membrane polypeptides | 3 genes |
| DUF813, Arabidopsis thaliana protein of unknown function (DUF813). This family consists of several uncharacterised proteins from Arabidopsis thaliana | 3 genes |
| DUF821, Arabidopsis thaliana protein of unknown function (DUF821). This family consists of a group of Arabidopsis thaliana proteins with no known function | 3 genes |
| DLIC, Dynein light intermediate chain (DLIC). This family consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-tran | 3 genes |
| DUF846, Eukaryotic protein of unknown function (DUF846). This family consists of several of unknown function from a variety of eukaryotic organisms | 3 genes |
| DUF862, Eukaryotic protein of unknown function (DUF862). This family consists of the N terminal portion of several eukaryotic sequences and is found in both animals and plants. The function of this family is unknown | 3 genes |
| DUF881, Bacterial protein of unknown function (DUF881). This family consists of a series of hypothetical bacterial proteins. One of the family members from Bacillus subtilis is thought to be involved in cell division and sporulation | 3 genes |
| DUF895, Eukaryotic protein of unknown function (DUF895). This family consists of several hypothetical eukaryotic proteins of unknown function | 3 genes |
| DUF1011, Protein of unknown function (DUF1011). Family of uncharacterised eukaryotic proteins | 3 genes |
| DUF1162, Protein of unknown function (DUF1162). This family represents a conserved region within several hypothetical eukaryotic proteins. Family members might be vacuolar protein sorting related-proteins. Vacuolar sorting protein is an ATPase | 3 genes |
| DUF1208, Protein of unknown function (DUF1208). This family consists of several eukaryotic sequences of around 270 residues in length. Members of this family are found in mouse, human and Drosophila melanogaster. The function of this family is | 3 genes |
| DUF1279, Protein of unknown function (DUF1279). This family represents the C-terminus (approx. 120 residues) of a number of eukaryotic proteins of unknown function | 3 genes |
| DUF1325, Protein of unknown function (DUF1325). This family consists of several hypothetical eukaryotic proteins of around 300 residues in length. The function of this family is unknown | 3 genes |
| DUF1356, Protein of unknown function (DUF1356). This family consists of several hypothetical mammalian proteins of around 250 residues in length. The function of this family is unknown | 3 genes |
| DUF1518, Domain of unknown function (DUF1518). This domain, which is usually found tandemly repeated, is found various receptor co-activating proteins | 3 genes |
| DNA replication and chromosome cycle, IEA | 3 genes |
| DNA binding, IC | 3 genes |
| delta DNA polymerase activity, TAS | 3 genes |
| DNA ligase (ATP) activity, IEA | 3 genes |
| DNA photolyase activity, IEA | 3 genes |
| DNA topoisomerase type I activity, IEA | 3 genes |
| dodecenoyl-CoA delta-isomerase activity, IEA | 3 genes |
| dimethylaniline monooxygenase (N-oxide-forming) activity, IEA | 3 genes |
| dopamine beta-monooxygenase activity, IEA | 3 genes |
| deoxyribonuclease activity, TAS | 3 genes |
| delta-DNA polymerase cofactor complex, TAS | 3 genes |
| dynactin complex, TAS | 3 genes |
| DNA metabolism, NR | 3 genes |
| DNA replication, NR | 3 genes |
| double-strand break repair via nonhomologous end-joining, TAS | 3 genes |
| DNA modification, IEA | 3 genes |
| DNA recombination, NAS | 3 genes |
| DNA packaging, NR | 3 genes |
| defense response, NAS | 3 genes |
| determination of left/right symmetry, TAS | 3 genes |
| digestion, NAS | 3 genes |
| dipeptidyl-peptidase activity, IEA | 3 genes |
| DNA bending activity, NAS | 3 genes |
| diphosphoinositol-polyphosphate diphosphatase activity, ISS | 3 genes |
| drug transporter activity, IEA | 3 genes |
| diuresis, TAS | 3 genes |
| dendrite, ISS | 3 genes |
| defense response to pathogen, IEA | 3 genes |
| DiHfolate_red, Dihydrofolate reductase | 2 genes |
| DNA_gyraseB, DNA gyrase B. This family represents the second domain of DNA gyrase B which has a ribosomal S5 domain 2-like fold. This family is structurally related to PF01119 | 2 genes |
| DNA_pol_viral_N, DNA polymerase (viral) N-terminal domain | 2 genes |
| dUTPase, dUTPase. dUTPase hydrolyses dUTP to dUMP and pyrophosphate | 2 genes |
| DHDPS, Dihydrodipicolinate synthetase family. This family has a TIM barrel structure | 2 genes |
| DNA_photolyase, DNA photolyase. This domain binds a light harvesting cofactor | 2 genes |
| DHO_dh, Dihydroorotate dehydrogenase | 2 genes |
| Diphthamide_syn, Putative diphthamide synthesis protein. One member is a candidate tumour suppressor gene. DPH2 from yeast, which confers resistance to diphtheria toxin has been found to be involved in diphthamide synthesis. Diphtheria toxin i | 2 genes |
| DUF59, Domain of unknown function DUF59. This family includes prokaryotic proteins of unknown function. The family also includes PhaH from Pseudomonas putida. PhaH forms a complex with PhaF, PhaG and PhaI, which hydroxylates phenylacetic acid | 2 genes |
| DUF89, Protein of unknown function DUF89. This family has no known function | 2 genes |
| DUF101, Protein of unknown function DUF101. The members of this family are uncharacterised. The alignment of these proteins contains several conserved polar residues that might be potential catalytic residues | 2 genes |
| DUF173, Uncharacterised ACR, COG1354 | 2 genes |
| DUF227, Domain of unknown function (DUF227). This family includes a large number of drosophila proteins of unknown function. The family also includes several C. elegans proteins. The alignment contains many histidines and aspartates that are c | 2 genes |
| DUF254, SAND. Members of this family are uncharacterised proteins that have been called SAND proteins. These proteins do not contain a SAND domain. The members of this family are 500-600 amino acids long and contain several conserved motifs. T | 2 genes |
| DNase_II, Deoxyribonuclease II | 2 genes |
| DUF323, Domain of unknown function (DUF323). This presumed domain is found in bacterial proteins. In some cases these proteins also contain a protein kinase domain. The function of this domain is unknown | 2 genes |
| DTW, DTW domain. This presumed domain is found in bacterial and eukaryotic proteins. Its function is unknown. The domain contains multiple conserved motifs including a DTXW motif that this domain has been named after | 2 genes |
| DNA_pol_E_B, DNA polymerase epsilon subunit B. DNA polymerase epsilon is essential for cell viability and chromosomal DNA replication in budding yeast. In addition, DNA polymerase epsilon may be involved in DNA repair and cell-cycle checkpoint | 2 genes |
| DNA_pol_alpha_B, DNA polymerase alpha subunit B. The B subunit of the DNA polymerase alpha plays an essential role at the initial stage of DNA replication in S. cerevisiae and is phosphorylated in a cell cycle-dependent manner | 2 genes |
| Dopey_N, Dopey, N-terminal. DopA is the founding member of the Dopey family and is required for correct cell morphology and spatiotemporal organisation of multicellular structures in the filamentous fungus Aspergillus nidulans. DopA homologues | 2 genes |
| Dor1, Dor1-like family. Dor1 is involved in vesicle targeting to the yeast Golgi apparatus and complexes with a number of other trafficking proteins, which include Sec34 and Sec35 | 2 genes |
| DUF525, Protein of unknown function (DUF525). Members of this family include the bacterial protein ApaG and the C termini of some F-box proteins (pfam00646). F-box proteins contain a carboxy-terminal domain that interacts with protein substrat | 2 genes |
| DUF541, Protein of unknown function (DUF541). Members of this family have so far been found in bacteria and mouse. However possible family members have also been identified in translated rat (Genbank:AW144450) and human (Genbank:AI478629) ESTs | 2 genes |
| DUF544, Protein of unknown function (DUF544). Eukaryotic protein of unknown function | 2 genes |
| DUF563, Protein of unknown function (DUF563). Family of uncharacterised proteins | 2 genes |
| DUF571, Protein of unknown function (DUF571). Family of hypothetical bacterial proteins | 2 genes |
| DUF598, Protein of unknown function, DUF598. This family contains several uncharacterised proteins | 2 genes |
| DUF607, Protein of unknown function, DUF607. This family represents a conserved region found in several uncharacterized eukaryotic proteins | 2 genes |
| DIE2_ALG10, DIE2/ALG10 family. The ALG10 protein from Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum. This protein has been characterised in rat as potassium channel regulator 1 | 2 genes |
| DUF676, Putative serine esterase (DUF676). This family of proteins are probably serine esterase type enzymes | 2 genes |
| DUF704, Aha1 domain. The function of this presumed domain is unknown. It is found in a range of bacterial as well as eukaryotic proteins. This domain is found in Aha1, which is found to interact with Hsp90. It is not certain if this interactio | 2 genes |
| DUF714, Domain of unknown function. This family of proteins has no known function. This region may contain transmembrane alpha helices. The domain is found in a variety of metazoan species | 2 genes |
| DUF737, Protein of unknown function (DUF737). This family consists of several uncharacterised mammalian proteins of unknown function | 2 genes |
| DUF719, Protein of unknown function (DUF719). This family consists of several eukaryotic proteins of unknown function | 2 genes |
| DUF740, Protein of unknown function (DUF740). This family consists of several uncharacterised plant proteins of unknown function | 2 genes |
| DUF773, Protein of unknown function (DUF773). This family contains several eukaryotic sequences which are thought to be CDK5 activator-binding proteins, however, the function of this family is unknown | 2 genes |
| DUF783, Protein of unknown function (DUF783). This family consists of several eukaryotic proteins of unknown function | 2 genes |
| DUF800, Protein of unknown function (DUF800). This family consists of several eukaryotic proteins of unknown function | 2 genes |
| DcpS, Scavenger mRNA decapping enzyme (DcpS). This family consists of several scavenger mRNA decapping enzymes (DcpS). DcpS is a scavenger pyrophosphatase that hydrolyses the residual cap structure following 3' to 5' decay of an mRNA. The asso | 2 genes |
| DUF814, Domain of unknown function (DUF814). This domain occurs in proteins that have been annotated as Fibronectin/fibrinogen binding protein by similarity. This annotation comes from a sequence, where the N-terminal region is involved in thi | 2 genes |
| DUF837, Protein of unknown function (DUF837). This family consists of several eukaryotic proteins of unknown function. One of the family members is a circulating cathodic antigen (CCA) found in Schistosoma mansoni (Blood fluke) | 2 genes |
| DUF858, Eukaryotic protein of unknown function (DUF858). This family consists of several eukaryotic proteins of unknown function | 2 genes |
| DUF872, Eukaryotic protein of unknown function (DUF872). This family consists of several uncharacterised eukaryotic proteins. The function of this family is unknown | 2 genes |
| DUF902, Domain of Unknown Function (DUF902) | 2 genes |
| DUF904, Protein of unknown function (DUF904). This family consists of several bacterial and archaeal hypothetical proteins of unknown function | 2 genes |
| DUF906, Domain of Unknown Function (DUF906) | 2 genes |
| DUF926, Domain of Unknown Function (DUF926). Family of eukaryotic proteins with undetermined function | 2 genes |
| DCP1, Dcp1-like decapping family. An essential step in mRNA turnover is decapping. In yeast, two proteins have been identified that are essential for decapping, Dcp1 (this family) and Dcp2 (pfam05026). The precise role of these proteins in the | 2 genes |
| DUF941, Domain of unknown function (DUF941). Family of eukaryotic proteins with unknown function | 2 genes |
| DUF947, Domain of unknown function (DUF947). Family of eukaryotic proteins with unknown function | 2 genes |
| DUF1000, Domain of Unknown Function (DUF1000) | 2 genes |
| DUF1086, Domain of Unknown Function (DUF1086). This family consists of several eukaryotic domains of unknown function which are present in chromodomain helicase DNA binding proteins. This domain is often found in conjunction with pfam00176, pf | 2 genes |
| DUF1087, Domain of Unknown Function (DUF1087) | 2 genes |
| DUF1088, Domain of Unknown Function (DUF1088). This family is found in the neurobeachins. The function of this region is not known | 2 genes |
| DUF1115, Protein of unknown function (DUF1115). This family represents the C-terminus of hypothetical eukaryotic proteins of unknown function | 2 genes |
| DUF1126, Repeat of unknown function (DUF1126). This family consists of several eukaryote specific repeats of around 35 residues in length. The function of this family is unknown | 2 genes |
| DUF1151, Protein of unknown function (DUF1151). This family consists of several hypothetical eukaryotic proteins of unknown function | 2 genes |
| DUF1170, Protein of unknown function (DUF1170). This family represents a conserved region of unknown function within MAGUIN, a neuronal membrane-associated guanylate kinase-interacting protein. This region is situated between the pfam00595 and | 2 genes |
| DUF1180, Protein of unknown function (DUF1180). This family consists of several hypothetical mammalian proteins of around 190 residues in length. The function of this family is unknown | 2 genes |
| DUF1222, Protein of unknown function (DUF1222). This family, which includes bacterial and eukaryotic members, represents a conserved region located towards the C-terminal end of a number of hypothetical proteins of unknown function. These are | 2 genes |
| DUF1226, Protein of unknown function (DUF1226). This family consists of several hypothetical eukaryotic proteins of unknown function | 2 genes |
| DUF1242, Protein of unknown function (DUF1242). This family consists of a number of eukaryotic proteins of around 72 residues in length. The function of this family is unknown | 2 genes |
| DUF1253, Protein of unknown function (DUF1253). This family represents the C-terminal portion (approximately 500 residues) of several hypothetical eukaryotic proteins of unknown function | 2 genes |
| DUF1295, Protein of unknown function (DUF1295). This family contains a number of bacterial and eukaryotic proteins of unknown function that are approximately 300 residues long | 2 genes |
| DUF1370, Protein of unknown function (DUF1370). This family consists of several hypothetical eukaryotic proteins of around 200 residues in length. Members of this family seem to be specific to mammals and their function is unknown | 2 genes |
| DUF1387, Protein of unknown function (DUF1387). This family represents a conserved region approximately 300 residues long within a number of hypothetical proteins of unknown function that seem to be restricted to mammals | 2 genes |
| DGCR6, DiGeorge syndrome critical region 6 (DGCR6) protein. This family contains DiGeorge syndrome critical region 6 (DGCR6) proteins (approximately 200 residues long) of a number of vertebrates. DGCR6 is a candidate for involvement in the DiG | 2 genes |
| DUF1487, Protein of unknown function (DUF1487). This family consists of several uncharacterised proteins from Drosophila melanogaster. The function of this family is unknown | 2 genes |
| damaged DNA binding, NR | 2 genes |
| double-stranded DNA binding, IDA | 2 genes |
| double-stranded RNA binding, IDA | 2 genes |
| DNA (cytosine-5-)-methyltransferase activity, TAS | 2 genes |
| DNA primase activity, TAS | 2 genes |
| DNA topoisomerase (ATP-hydrolyzing) activity, IEA | 2 genes |
| dihydroorotate dehydrogenase activity, IEA | 2 genes |
| dihydroorotate oxidase activity, IEA | 2 genes |
| dolichyl-phosphate-mannose-protein mannosyltransferase activity, IEA | 2 genes |
| dimethylaniline monooxygenase (N-oxide-forming) activity, NAS | 2 genes |
| dolichyl-diphosphooligosaccharide-protein glycotransferase activity, IEA | 2 genes |
| DNA-directed RNA polymerase III complex, NAS | 2 genes |
| DNA-directed RNA polymerase III complex, TAS | 2 genes |
| DNA ligation, TAS | 2 genes |
| DNA unwinding, NAS | 2 genes |
| DNA replication, synthesis of RNA primer, TAS | 2 genes |
| DNA strand elongation, TAS | 2 genes |
| DNA methylation, IDA | 2 genes |
| DNA methylation, ISS | 2 genes |
| DNA dealkylation, TAS | 2 genes |
| DNA recombination, ISS | 2 genes |
| DNA recombination, NR | 2 genes |
| DNA transposition, IEA | 2 genes |
| DNA replication-dependent nucleosome assembly, TAS | 2 genes |
| dicarboxylic acid transport, TAS | 2 genes |
| DNA damage induced protein phosphorylation, TAS | 2 genes |
| dopamine receptor, adenylate cyclase activating pathway, TAS | 2 genes |
| development, IEP | 2 genes |
| digestion, ISS | 2 genes |
| DNA-dependent ATPase activity, TAS | 2 genes |
| drug binding, NR | 2 genes |
| determination of anterior/posterior axis, embryo, NAS | 2 genes |
| deoxyribonucleoside diphosphate metabolism, IEA | 2 genes |
| detection of virus, NAS | 2 genes |
| dimethylargininase activity, IEA | 2 genes |
| D-amino acid catabolism, IEA | 2 genes |
| desmosome, NAS | 2 genes |
| dendrite, NAS | 2 genes |
| Dehydrin, Dehydrin | 1 genes |
| DapB_N, Dihydrodipicolinate reductase, N-terminus. Dihydrodipicolinate reductase (DapB) reduces the alpha,beta-unsaturated cyclic imine, dihydro-dipicolinate. This reaction is the second committed step in the biosynthesis of L-lysine and its p | 1 genes |
| DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure pfam00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyse one step in prokaryotic | 1 genes |
| DHH, DHH family. It is predicted that this family of proteins all perform a phosphoesterase function. It included the single stranded DNA exonuclease RecJ | 1 genes |
| DUF28, Domain of unknown function DUF28. This domain is found in bacterial and yeast proteins it compromises the entire length or central region of most of the proteins in the family, all of which are hypothetical with no known function. The a | 1 genes |
| DUF32, Domain of unknown function DUF32. This domain is found in hypothetical C. elegans proteins all of which are function unknown. The aligned region is approximately 160 amino acids long | 1 genes |
| DeoC, Deoxyribose-phosphate aldolase. This family includes the enzyme deoxyribose-phosphate aldolase EC:4.1.2.4, which is involved in nucleotide metabolism. The family also includes a group of related bacterial proteins of unknown function | 1 genes |
| DNA_primase_S, DNA primase small subunit. DNA primase synthesises the RNA primers for the Okazaki fragments in lagging strand DNA synthesis. DNA primase is a heterodimer of large and small subunits | 1 genes |
| DUF75, Protein of unknown function DUF75. Archaebacterial proteins of unknown function. Members of this family may be transmembrane proteins. Several of the family members are thought to be 3-isopropylmalate dehydratase | 1 genes |
| DS, Deoxyhypusine synthase. Eukaryotic initiation factor 5A (eIF-5A) contains an unusual amino acid, hypusine [N epsilon-(4-aminobutyl-2-hydroxy)lysine]. The first step in the post-translational formation of hypusine is catalysed by the enzyme | 1 genes |
| DUF82, Protein of unknown function DUF82. This prokaryotic protein family has no known function. The protein contains four conserved cysteines that may be involved in metal binding or disulphide bridges | 1 genes |
| DUF84, Protein of unknown function DUF84. The function of this prokaryotic protein family is unknown | 1 genes |
| DUF92, Integral membrane protein DUF92. Members of this family have several predicted transmembrane helices. The function of these prokaryotic proteins is unknown | 1 genes |
| DUF108, Domain of unknown function DUF108. This family has no known function. It is found to compose the complete protein in archaebacteria and a single domain in a large C. elegans protein | 1 genes |
| dsDNA_bind, Double-stranded DNA-binding domain. This domain is believed to bind double-stranded DNA of 20 bases length | 1 genes |
| DAD, DAD family. Members of this family are thought to be integral membrane proteins. Some members of this family have been shown to cause apoptosis if mutated, these proteins are known as DAD for defender against death. The family also includ | 1 genes |
| DHHA1, DHHA1 domain. This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, sug | 1 genes |
| DUF141, Domain of unknown function DUF141. This is a family of hypothetical C. elegans proteins. The aligned region has no known function nor do any of the proteins which possess it. The aligned region is approximately 130 amino acids long and | 1 genes |
| DUF143, Domain of unknown function DUF143. This domain has no known function nor do any of the proteins that possess it. The aligned region is approximately 100 amino acids long | 1 genes |
| DUF152, Uncharacterised ACR, YfiH family COG1496 | 1 genes |
| DUF155, Uncharacterised ACR, YagE family COG1723 | 1 genes |
| DUF158, Uncharacterised LmbE-like protein, COG2120 | 1 genes |
| DUF159, Uncharacterised ACR, COG2135 | 1 genes |
| DUF167, Uncharacterized ACR, YggU family COG1872 | 1 genes |
| DUF171, Uncharacterized ACR, COG2106 | 1 genes |
| DUF185, Uncharacterized ACR, COG1565. This family contains several uncharacterized proteins. One member has been described as an ATP synthase beta subunit transcription termination factor rho protein | 1 genes |
| DUF207, Uncharacterized ACR, COG1590 | 1 genes |
| Dak1, Dak1 domain. This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29 | 1 genes |
| Dak2, DAK2 domain. This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family | 1 genes |
| DHHA2, DHHA2 domain. This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members. The domain is about 120 residues long and contains a cons | 1 genes |
| DUF248, Putative methyltransferase. Members of this family of hypothetical plant proteins are probably methyltransferases: several of the aligned sequences either match a methyltransferase profile or contain a SAM-binding motif; one member con | 1 genes |
| DUF255, Protein of unknown function, DUF255 | 1 genes |
| DUF265, Protein of unknown function, DUF265 | 1 genes |
| DDOST_48kD, Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kD subunit. Members of this family are involved in asparagine-linked protein glycosylation. In particular, dolichyl-diphosphooligosaccharide-protein glycosyltransferas | 1 genes |
| DUF278, DUF278. This is a family of C. elegans proteins | 1 genes |
| DUF283, Domain of unknown function. This putative domain is found in members of the Dicer protein family. This protein is a dsRNA nuclease that is involved in RNAi and related processes. This domain of about 100 amino acids has no known functi | 1 genes |
| DUF280, Caenorhabditis protein of unknown function, DUF280 | 1 genes |
| DUF292, Eukaryotic protein of unknown function, DUF292 | 1 genes |
| DNA_RNApol_7kD, DNA directed RNA polymerase, 7 kDa subunit | 1 genes |
| DUF335, Putative metallopeptidase (SprT family). This family of uncharacterised proteins may be zinc metallopeptidases | 1 genes |
| DUF341, Domain of unknown function (DUF341) | 1 genes |
| DUF367, Domain of unknown function (DUF367) | 1 genes |
| DUF382, Domain of unknown function (DUF382). This domain is specific to the human splicing factor 3b subunit 2 and it's orthologues. Splicing factor 3b subunit 2 or SAP145 is a suppressor of U2 snRNA mutations. Pre-mRNA splicing is catalysed b | 1 genes |
| DUF383, Domain of unknown function (DUF383) | 1 genes |
| DUF384, Domain of unknown function (DUF384) | 1 genes |
| DNA_pol_delta_4, DNA polymerase delta, subunit 4 | 1 genes |
| DNA_primase_lrg, Eukaryotic-type DNA primase, large subunit. DNA primase is the polymerase that synthesises small RNA primers for the Okazaki fragments made during discontinuous DNA replication. DNA primase is a heterodimer of two subunits, th | 1 genes |
| DFP, DNA / pantothenate metabolism flavoprotein. The DNA/pantothenate metabolism flavoprotein (EC:4.1.1.36) affects synthesis of DNA, and pantothenate metabolism | 1 genes |
| DUF396, Protein of unknown function (DUF396). A family of conserved eukaryotic transmembrane proteins | 1 genes |
| DUF408, Domain of Unknown Function (DUF408) | 1 genes |
| DUF409, Protein of unknown function (DUF409). Family of eukaryotic membrane proteins with unknown function | 1 genes |
| DUF410, Protein of unknown function (DUF410). Family of conserved eukaryotic proteins with undetermined function | 1 genes |
| DUF423, Protein of unknown function (DUF423). Potential integral membrane protein | 1 genes |
| DUF500, Family of unknown function (DUF500). Proteins in this family often also contain an SH3 domain (pfam00018), or a FYVE zinc finger (pfam01363) | 1 genes |
| DUF537, Protein of unknown function, DUF537. This family represents a conserved region of unknown function within plant proteins. Some family members have one or more zinc-finger motifs towards the C-terminus | 1 genes |
| DUF543, Domain of unknown function (DUF543). This family of short eukaryotic proteins has no known function. Most of the members of this family are only 80 amino acid residues long. However the Arabidopsis homologue is over 300 residues long. | 1 genes |
| DUF498, Protein of unknown function (DUF498). Family of uncharacterised proteins. Possibly involved in DNA repair | 1 genes |
| DUF549, Family of unknown function (DUF549). Family of uncharacterised eukaryotic proteins | 1 genes |
| DUF589, Family of unknown function (DUF589). Family of uncharacterised proteins | 1 genes |
| DUF602, Protein of unknown function, DUF602. This family represents several uncharacterised eukaryotic proteins | 1 genes |
| DUF608, Protein of unknown function, DUF608. This family represents a conserved region with a pankaryotic distribution in a number of uncharacterised proteins | 1 genes |
| DUF750, Domain of unknown function (DUF750). Domain of unknown function that is found eukaryotic protein. There can be between 1 and 3 copies of this domain per protein. The domain is commonly associated with Transglutaminase-like domains (pfa | 1 genes |
| DUF611, Protein of unknown function, DUF611. This family includes several uncharacterised Bacillus halodurans proteins | 1 genes |
| DUF619, Protein of unknown function (DUF619). This region of unknown function is found at the C-terminus of Neurospora crassa acetylglutamate synthase (amino-acid acetyltransferase, EC: 2.3.1.1). It is also found C-terminal to the amino acid k | 1 genes |
| DUF632, Protein of unknown function (DUF632). This plant protein may be a leucine zipper, but there is no experimental evidence for this | 1 genes |
| DUF622, Protein of unknown function, DUF622. This family includes several uncharacterised mouse proteins | 1 genes |
| DUF647, Protein of unknown function, DUF647 | 1 genes |
| DUF654, Protein of unknown function, DUF654. This family includes a number of poorly characterised eukaryotic proteins | 1 genes |
| Dynamitin, Dynamitin. Dynamitin is a subunit of the microtubule-dependent motor complex and in implicated in cell adhesion by binding to macrophage-enriched myristoylated alanine-rice C kinase substrate (MacMARCKS) | 1 genes |
| DUF662, Family of unknown function (DUF662). Family of hypothetical eukaryotic proteins | 1 genes |
| DBR1, Lariat debranching enzyme, C-terminal domain. This presumed domain is found at the C-terminus of lariat debranching enzyme. This domain is always found in association with pfam00149 | 1 genes |
| DCP2, Dcp2, box A domain. This presumed domain is always found to the amino terminal side of pfam00293. This domain appears to be specific to mRNA decapping protein 2 and its close homologues. This region has been termed Box A | 1 genes |
| DUF677, Protein of unknown function (DUF677). This family consists of AT14A like proteins from Arabidopsis thaliana. At14a has a small domain that has sequence similarities to integrins from fungi, insects and humans. Transcripts of At14a are | 1 genes |
| DUF689, Protein of unknown function (DUF689). This family contains several uncharacterised eukaryotic proteins of unknown function | 1 genes |
| DivIVA, DivIVA protein. The Bacillus subtilis divIVA1 mutation causes misplacement of the septum during cell division, resulting in the formation of small, circular, anucleate minicells. Inactivation of divIVA produces a minicell phenotype, wh | 1 genes |
| DUF699, Putative ATPase (DUF699). This putative domain is about 350 amino acid residues long and appears to have a P-loop motif, suggesting this is an ATPase. This domain is often associated with pfam00583. This domain is found in isolation in | 1 genes |
| DUF701, Putative zinc binding domain (DUF701). This family of short proteins contains a putative zinc binding domain with four conserved cysteines | 1 genes |
| DUF702, Domain of unknown function (DUF702). Family of uncharacterised plant proteins | 1 genes |
| DUF706, Family of unknown function (DUF706). Family of uncharacterised eukaryotic function. Some members have a described putative function, but a common theme is not evident | 1 genes |
| DSS1_SEM1, DSS1/SEM1 family. This family contains SEM1 and DSS1 which are short acidic proteins | 1 genes |
| DUF712, Protein of unknown function (DUF712). This family of proteins is functionally uncharacterised | 1 genes |
| DUF715, Protein of unknown function (DUF715). This family of eukaryotic proteins has no characterised function. The alignment contains some conserved cysteine and histidines that might form a zinc binding site (Bateman A pers obs) | 1 genes |
| DREV, DREV methyltransferase. This family contains DREV protein homologues from several eukaryotes. The function of this protein is unknown. However, these proteins appear to be related to other methyltransferases (Bateman A pers obs) | 1 genes |
| DUF738, Protein of unknown function (DUF738). This family consists of several uncharacterised eukaryotic proteins of unknown function | 1 genes |
| DUF720, Protein of unknown function (DUF720). This family consists of several uncharacterised Chlamydia proteins of unknown function | 1 genes |
| DUF727, Protein of unknown function (DUF727). This family consists of several uncharacterised eukaryotic proteins of unknown function | 1 genes |
| DUF747, Eukaryotic membrane protein (cytomegalovirus gH-receptor) family. This family of eukaryotic membrane proteins includes the putative receptor for human cytomegalovirus gH. The cellular function of this family remains unknown | 1 genes |
| DegS, Sensor protein DegS. This is small family of Bacillus DegS proteins. The DegS-DegU two-component regulatory system of Bacillus subtilis controls various processes that characterise the transition from the exponential to the stationary gr | 1 genes |
| DMAP1, DNA methyltransferase 1-associated protein 1 (DMAP1). DNA methylation can contribute to transcriptional silencing through several transcriptionally repressive complexes, which include methyl-CpG binding domain proteins (MBDs) and histon | 1 genes |
| Dynactin_p62, Dynactin p62 family. Dynactin is a multi-subunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein. p62 binds directly to the Arp1 subunit of dyn | 1 genes |
| DUF757, Domain of Unknown Function (DUF757). Family of eukaryotic proteins with undetermined function | 1 genes |
| DUF761, Cotton fibre expressed protein. This family consists of several plant proteins of unknown function. Three of the sequences (from Gossypium hirsutum) in this family are described as cotton fibre expressed proteins. The remaining sequenc | 1 genes |
| DUF766, Protein of unknown function (DUF766). This family consists of several eukaryotic proteins of unknown function | 1 genes |
| DUF775, Protein of unknown function (DUF775). This family consists of several eukaryotic proteins of unknown function | 1 genes |
| DUF776, Protein of unknown function (DUF776). This family consists of several highly related mouse and human proteins of unknown function | 1 genes |
| DUF778, Protein of unknown function (DUF778). This family consists of several eukaryotic proteins of unknown function | 1 genes |
| DUF781, Mouse protein of unknown function (DUF781). This family consists of uncharacterised mouse proteins of unknown function | 1 genes |
| DUF788, Protein of unknown function (DUF788). This family consists of several eukaryotic proteins of unknown function | 1 genes |
| DUF791, Protein of unknown function (DUF791). This family consists of several eukaryotic proteins of unknown function | 1 genes |
| DUF786, Protein of unknown function (DUF786). This family consists of several eukaryotic proteins of unknown function | 1 genes |
| DUF815, Protein of unknown function (DUF815). This family consists of several bacterial proteins of unknown function | 1 genes |
| DUF822, Plant protein of unknown function (DUF822). This family consists of the N terminal regions of several plant proteins of unknown function | 1 genes |
| DUF829, Eukaryotic protein of unknown function (DUF829). This family consists of several uncharacterised eukaryotic proteins | 1 genes |
| DUF833, Protein of unknown function (DUF833). This family is found in eukaryotes, prokaryotes and viruses and has no known function. One member has been found to be expressed during early embryogenesis in mice | 1 genes |
| DUF841, Eukaryotic protein of unknown function (DUF841). This family consists of several eukaryotic proteins with no known function | 1 genes |
| DUF842, Eukaryotic protein of unknown function (DUF842). This family consists of a number of conserved eukaryotic proteins of unknown function | 1 genes |
| DUF850, Eukaryotic protein of unknown function (DUF850). This family consists of several eukaryotic putative membrane proteins of unknown function | 1 genes |
| DUF852, Eukaryotic protein of unknown function (DUF852). This family consists of several eukaryotic proteins with no known function. The family contains a fragment match to a protein, which is thought to be a ubiquitin carrier protein | 1 genes |
| DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. One member is thought to be an ATPase | 1 genes |
| DUF855, Baculovirus protein of unknown function (DUF855). This family consists of several Baculovirus proteins of around 130 residues in length. The function of this family is unknown | 1 genes |
| DUF866, Eukaryotic protein of unknown function (DUF866). This family consists of a number of hypothetical eukaryotic proteins of unknown function with an average length of around 165 residues | 1 genes |
| DUF885, Bacterial protein of unknown function (DUF885). This family consists of several hypothetical bacterial proteins several of which are putative membrane proteins | 1 genes |
| DUF890, Protein of unknown function (DUF890). This family consists of several conserved hypothetical proteins from both eukaryotes and prokaryotes. The function of this family is unknown | 1 genes |
| DUF894, Bacterial protein of unknown function (DUF894). This family consists of several bacterial proteins, many of which are annotated as putative transmembrane transport proteins | 1 genes |
| DUF900, Protein of unknown function (DUF900). This family consists of several hypothetical proteins of unknown function mostly found in Rhizobium species | 1 genes |
| DUF907, Fungal protein of unknown function (DUF907). This family consists of several hypothetical fungal proteins of unknown function | 1 genes |
| DUF921, Streptomyces protein of unknown function (DUF921). This family consists of several putative regulatory proteins from Streptomyces coelicolor and Streptomyces griseus. One of the sequences in this family is thought to be involved in spo | 1 genes |
| DUF933, Protein of unknown function (DUF933). This family consists of several GTP binding proteins and represents the C terminal domain of the constituent proteins. The family contains both prokaryotic and eukaryotic sequences which are highly | 1 genes |
| DUF938, Protein of unknown function (DUF938). This family consists of several hypothetical proteins from both prokaryotes and eukaryotes. The function of this family is unknown | 1 genes |
| DUF939, Bacterial protein of unknown function (DUF939). This family consists of several hypothetical bacterial proteins of unknown function | 1 genes |
| DUF953, Eukaryotic protein of unknown function (DUF953). This family consists of several hypothetical eukaryotic proteins of unknown function | 1 genes |
| DUF959, Domain of Unknown Function (DUF959). This N-terminal domain is not expressed in the 'Short' isoform of Collagen A | 1 genes |
| DUF972, Protein of unknown function (DUF972). This family consists of several hypothetical bacterial and one Caenorhabditis elegans sequence. The function of this family is unknown | 1 genes |
| DUF974, Protein of unknown function (DUF974). Family of uncharacterised eukaryotic proteins | 1 genes |
| DUF1032, Protein of unknown function (DUF1032). This family consists of several conserved eukaryotic proteins of unknown function | 1 genes |
| DUF1057, Protein of unknown function (DUF1057). This family consists of several Caenorhabditis elegans specific proteins of unknown function | 1 genes |
| DUF1075, Protein of unknown function (DUF1075). This family consists of several eukaryotic proteins of unknown function | 1 genes |
| DUF1077, Protein of unknown function (DUF1077). This family consists of several hypothetical eukaryotic proteins of unknown function | 1 genes |
| DUF1081, Domain of Unknown Function (DUF1081). This region is found in Apolipophorin proteins | 1 genes |
| DUF1090, Protein of unknown function (DUF1090). This family consists of several bacterial proteins of unknown function and is known as YqjC in E. coli | 1 genes |
| DUF1119, Protein of unknown function (DUF1119). This family consists of several hypothetical archaeal proteins of unknown function | 1 genes |
| DUF1135, Protein of unknown function (DUF1135). This family consists of several hypothetical mammalian proteins of unknown function | 1 genes |
| DIRP, DIRP. DIRP (Domain in Rb-related Pathway) is postulated to be involved in the Rb-related pathway, which is encoded by multiple eukaryotic genomes and is present in proteins including lin-9 of Caenorhabditis elegans, aly of fruit fly and | 1 genes |
| DUF1143, Protein of unknown function (DUF1143). This family consists of several hypothetical mammalian proteins (from mouse and human). The function of this family is unknown | 1 genes |
| DUF1154, Protein of unknown function (DUF1154). This family represents a small conserved region of unknown function within eukaryotic phospholipase C (EC:3.1.4.3). All members also contain pfam00387 and pfam00388 | 1 genes |
| DUF1171, Protein of unknown function (DUF1171). This family represents a conserved region of unknown function within a number of hypothetical eukaryotic proteins | 1 genes |
| DUF1183, Protein of unknown function (DUF1183). This family consists of several eukaryotic proteins of around 360 residues in length. The function of this family is unknown | 1 genes |
| DUF1191, Protein of unknown function (DUF1191). This family contains hypothetical plant proteins of unknown function | 1 genes |
| DUF1211, Protein of unknown function (DUF1211). This family represents a conserved region within a number of hypothetical proteins of unknown function found in eukaryotes, bacteria and archaea. These may possibly be integral membrane proteins | 1 genes |
| DiS_P_DiS, Bacterial Peptidase A24 N-terminal domain. This family is found at the N-terminus of the prepilin peptidases (pfam01478). It's function has not been specifically determined; however some of the family have been characterised as bifu | 1 genes |
| DUF1227, Protein of unknown function (DUF1227). This family represents a conserved region within a number of eukaryotic DNA repair helicases (EC:3.6.1.-) | 1 genes |
| DUF1232, Protein of unknown function (DUF1232). This family represents a conserved region of approximately 60 residues within a number of hypothetical bacterial and archaeal proteins of unknown function | 1 genes |
| DUF1241, Protein of unknown function (DUF1241). This family consists of several programmed cell death 10 protein (PDCD10 or TFAR15) sequences. The function of this family is unknown | 1 genes |
| DUF1301, Protein of unknown function (DUF1301). This family contains a number of eukaryotic proteins of unknown function that are approximately 160 residues long | 1 genes |
| DUF1308, Protein of unknown function (DUF1308). This family consists of several hypothetical eukaryotic sequences of around 400 residues in length. The function of this family is unknown | 1 genes |
| DUF1337, Protein of unknown function (DUF1337) | 1 genes |
| DUF1339, Protein of unknown function (DUF1339). This family represents a conserved region approximately 300 residues long within a number of hypothetical eukaryotic proteins of unknown function. These are possibly integral membrane proteins | 1 genes |
| D123, D123. This family contains a number of eukaryotic D123 proteins approximately 330 residues long. It has been shown that mutated variants of D123 exhibit temperature-dependent differences in their degradation rate | 1 genes |
| DUF1346, Protein of unknown function (DUF1346). This family consists of several hypothetical mammalian proteins of around 320 residues in length. The function of this family is unknown although several of the family members are annotated as pu | 1 genes |
| DUF1351, Protein of unknown function (DUF1351). This family consists of several bacterial and phage proteins of around 230 residues in length. The function of this family is unknown | 1 genes |
| DUF1352, Protein of unknown function (DUF1352). This family consists of several hypothetical eukaryotic proteins of around 190 residues in length. The function of this family is unknown | 1 genes |
| DUF1358, Protein of unknown function (DUF1358). This family consists of several hypothetical eukaryotic proteins of around 125 residues in length. The function of this family is unknown | 1 genes |
| DUF1395, Protein of unknown function (DUF1395). This family consists of several hypothetical eukaryotic proteins of around 250 residues in length. The function of this family is unknown | 1 genes |
| DAP10, DAP10 membrane protein. This family consists of several mammalian DAP10 membrane proteins. In activated mouse natural killer (NK) cells, the NKG2D receptor associates with two intracellular adaptors, DAP10 and DAP12, which trigger phosp | 1 genes |
| DUF1445, Protein of unknown function (DUF1445). This family represents a conserved region approximately 150 residues long within a number of hypothetical bacterial and eukaryotic proteins of unknown function | 1 genes |
| DUF1448, Protein of unknown function (DUF1448). This family consists of several eukaryotic proteins of around 375 residues in length. The function of this family is unknown | 1 genes |
| DPM2, Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2). This family consists of several eukaryotic dolichol phosphate-mannose biosynthesis regulatory (DPM2) proteins. Biosynthesis of glycosylphosphatidylinositol and N-glycan p | 1 genes |
| DUF1466, Protein of unknown function (DUF1466). This family consists of several hypothetical mammalian proteins of around 240 residues in length | 1 genes |
| Dynactin_p22, Dynactin subunit p22. This family contains p22, the smallest subunit of dynactin, a complex that binds to cytoplasmic dynein and is a required activator for cytoplasmic dynein-mediated vesicular transport. Dynactin localises to t | 1 genes |
| DNA replication and chromosome cycle, NR | 1 genes |
| DNA damage checkpoint, IMP | 1 genes |
| DNA damage checkpoint, ISS | 1 genes |
| double-strand break repair via homologous recombination, NAS | 1 genes |
| double-strand break repair via homologous recombination, TAS | 1 genes |
| DNA synthesis during DNA repair, NAS | 1 genes |
| DNA strand annealing activity, IDA | 1 genes |
| DNA binding, IMP | 1 genes |
| DNA helicase activity, IDA | 1 genes |
| DNA helicase activity, IEA | 1 genes |
| damaged DNA binding, ISS | 1 genes |
| double-stranded DNA binding, NAS | 1 genes |
| double-stranded RNA binding, ISS | 1 genes |
| double-stranded RNA binding, NAS | 1 genes |
| double-stranded RNA adenosine deaminase activity, TAS | 1 genes |
| D-amino-acid oxidase activity, IEA | 1 genes |
| D-amino-acid oxidase activity, TAS | 1 genes |
| DNA (cytosine-5-)-methyltransferase activity, IDA | 1 genes |
| DNA (cytosine-5-)-methyltransferase activity, IEA | 1 genes |
| DNA (cytosine-5-)-methyltransferase activity, ISS | 1 genes |
| DNA-directed DNA polymerase activity, NAS | 1 genes |
| DNA-directed DNA polymerase activity, NR | 1 genes |
| DNA-directed DNA polymerase activity, TAS | 1 genes |
| delta DNA polymerase activity, NAS | 1 genes |
| DNA-directed RNA polymerase activity, IEP | 1 genes |
| DNA-directed RNA polymerase activity, NR | 1 genes |
| DNA-(apurinic or apyrimidinic site) lyase activity, IDA | 1 genes |
| DNA-(apurinic or apyrimidinic site) lyase activity, TAS | 1 genes |
| DNA ligase (ATP) activity, TAS | 1 genes |
| DNA nucleotidylexotransferase activity, IEA | 1 genes |
| DNA nucleotidylexotransferase activity, TAS | 1 genes |
| DNA topoisomerase type I activity, TAS | 1 genes |
| DNA topoisomerase (ATP-hydrolyzing) activity, TAS | 1 genes |
| dCMP deaminase activity, TAS | 1 genes |
| deoxycytidine kinase activity, TAS | 1 genes |
| deoxyguanosine kinase activity, TAS | 1 genes |
| dephospho-CoA kinase activity, IEA | 1 genes |
| diacylglycerol cholinephosphotransferase activity, ISS | 1 genes |
| diacylglycerol cholinephosphotransferase activity, TAS | 1 genes |
| diacylglycerol kinase activity, NAS | 1 genes |
| diacylglycerol O-acyltransferase activity, IDA | 1 genes |
| diacylglycerol O-acyltransferase activity, TAS | 1 genes |
| diamine N-acetyltransferase activity, TAS | 1 genes |
| dihydrofolate reductase activity, IEA | 1 genes |
| dihydrofolate reductase activity, NAS | 1 genes |
| dihydrolipoyl dehydrogenase activity, TAS | 1 genes |
| dihydrolipoyllysine-residue succinyltransferase activity, IEA | 1 genes |
| dihydrolipoyllysine-residue succinyltransferase activity, NAS | 1 genes |
| dihydroorotase activity, IEA | 1 genes |
| dihydroorotate dehydrogenase activity, NAS | 1 genes |
| dihydropteroate synthase activity, IEA | 1 genes |
| dimethylallyltranstransferase activity, IEA | 1 genes |
| diphosphomevalonate decarboxylase activity, TAS | 1 genes |
| diphthine synthase activity, IEA | 1 genes |
| dopachrome isomerase activity, IEA | 1 genes |
| dopachrome isomerase activity, TAS | 1 genes |
| dolichyl-phosphate-mannose-protein mannosyltransferase activity, TAS | 1 genes |
| dUTP diphosphatase activity, TAS | 1 genes |
| dipeptidyl-peptidase I activity, IEA | 1 genes |
| dipeptidyl-peptidase IV activity, NAS | 1 genes |
| dipeptidyl-peptidase IV activity, TAS | 1 genes |
| deoxyribonuclease I activity, IEA | 1 genes |
| deoxyribonuclease II activity, IEA | 1 genes |
| deoxyribonuclease II activity, TAS | 1 genes |
| deoxyribonuclease activity, IEA | 1 genes |
| dolichyl-diphosphooligosaccharide-protein glycotransferase activity, TAS | 1 genes |
| dolichyl-phosphate beta-glucosyltransferase activity, IEA | 1 genes |
| dolichyl-phosphate beta-D-mannosyltransferase activity, TAS | 1 genes |
| DNA-dependent protein kinase activity, TAS | 1 genes |
| diacylglycerol-activated phospholipid-dependent protein kinase C activity, TAS | 1 genes |
| dihydrolipoyllysine-residue acetyltransferase activity, IEA | 1 genes |
| dihydrolipoyllysine-residue acetyltransferase activity, NAS | 1 genes |
| dopamine receptor activity, IEA | 1 genes |
| delta-opioid receptor activity, TAS | 1 genes |
| death receptor activity, TAS | 1 genes |
| death receptor binding, ISS | 1 genes |
| death receptor binding, NAS | 1 genes |
| delayed rectifier potassium channel activity, IDA | 1 genes |
| delayed rectifier potassium channel activity, NR | 1 genes |
| dicarboxylic acid transporter activity, TAS | 1 genes |
| dopamine:sodium symporter activity, IEA | 1 genes |
| delta DNA polymerase complex, NAS | 1 genes |
| delta-DNA polymerase cofactor complex, NAS | 1 genes |
| DNA-directed RNA polymerase II, core complex, IC | 1 genes |
| DNA-directed RNA polymerase II, core complex, IEA | 1 genes |
| DNA-directed RNA polymerase II, core complex, ISS | 1 genes |
| DNA-directed RNA polymerase II, core complex, NAS | 1 genes |
| DNA-directed RNA polymerase III complex, IDA | 1 genes |
| DNA-directed RNA polymerase III complex, NR | 1 genes |
| DNA-directed RNA polymerase I complex, NAS | 1 genes |
| DNA-directed RNA polymerase I complex, TAS | 1 genes |
| dynactin complex, ISS | 1 genes |
| dynactin complex, NR | 1 genes |
| DNA-dependent protein kinase complex, IEA | 1 genes |
| DNA-dependent protein kinase complex, NAS | 1 genes |
| disaccharide metabolism, TAS | 1 genes |
| D-ribose metabolism, IEA | 1 genes |
| dADP biosynthesis, TAS | 1 genes |
| dTMP biosynthesis, IEA | 1 genes |
| dTDP biosynthesis, IEA | 1 genes |
| dTTP biosynthesis, IEA | 1 genes |
| DNA replication, ISS | 1 genes |
| DNA-dependent DNA replication, NAS | 1 genes |
| DNA unwinding, IMP | 1 genes |
| DNA replication, synthesis of RNA primer, NR | 1 genes |
| DNA replication initiation, NAS | 1 genes |
| DNA replication initiation, NR | 1 genes |
| DNA repair, IGI | 1 genes |
| DNA repair, ISS | 1 genes |
| double-strand break repair, NR | 1 genes |
| double-strand break repair via nonhomologous end-joining, IEA | 1 genes |
| DNA modification, TAS | 1 genes |
| DNA methylation, NAS | 1 genes |
| DNA fragmentation, NAS | 1 genes |
| DNA transposition, TAS | 1 genes |
| DNA packaging, NAS | 1 genes |
| diacylglycerol biosynthesis, ISS | 1 genes |
| diacylglycerol biosynthesis, TAS | 1 genes |
| defense response, IMP | 1 genes |
| defense response, ISS | 1 genes |
| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, IDA | 1 genes |
| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, NAS | 1 genes |
| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, TAS | 1 genes |
| DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, TAS | 1 genes |
| dopamine receptor, adenylate cyclase inhibiting pathway, TAS | 1 genes |
| determination of left/right symmetry, ISS | 1 genes |
| determination of left/right symmetry, NAS | 1 genes |
| drug binding, NAS | 1 genes |
| drug binding, TAS | 1 genes |
| dipeptidyl-peptidase activity, NAS | 1 genes |
| dipeptidyl-peptidase activity, TAS | 1 genes |
| DNA bending activity, TAS | 1 genes |
| double-stranded DNA specific exodeoxyribonuclease activity, TAS | 1 genes |
| D-aspartate oxidase activity, TAS | 1 genes |
| dTDP-glucose 4,6-dehydratase activity, IEA | 1 genes |
| diphosphoinositol-polyphosphate diphosphatase activity, NR | 1 genes |
| determination of anterior/posterior axis, embryo, TAS | 1 genes |
| diuretic hormone activity, TAS | 1 genes |
| DNA damage response, signal transduction resulting in induction of apoptosis, IDA | 1 genes |
| D-alanyl-D-alanine endopeptidase activity, TAS | 1 genes |
| D-lactate dehydrogenase activity, ISS | 1 genes |
| dTDP-4-dehydrorhamnose reductase activity, IEA | 1 genes |
| DNA-methyltransferase activity, TAS | 1 genes |
| deoxyribonucleoside monophosphate biosynthesis, TAS | 1 genes |
| DNA supercoiling activity, IEP | 1 genes |
| detection of visible light, TAS | 1 genes |
| detection of sound, TAS | 1 genes |
| detection of chemical substance, TAS | 1 genes |
| detection of pathogenic bacteria, ISS | 1 genes |
| detection of pathogenic bacteria, NAS | 1 genes |
| dorsal/ventral pattern formation, ISS | 1 genes |
| DNA integration, TAS | 1 genes |
| drug transporter activity, TAS | 1 genes |
| drug transport, IEA | 1 genes |
| diadenosine polyphosphate catabolism, TAS | 1 genes |
| dystrophin-associated glycoprotein complex, ISS | 1 genes |
| detection of bacteria, TAS | 1 genes |
| detection of fungi, NAS | 1 genes |
| dephosphorylation, IDA | 1 genes |
| dephosphorylation, NAS | 1 genes |
| dendrite morphogenesis, IDA | 1 genes |
| dendrite morphogenesis, ISS | 1 genes |
| dipeptidase activity, NAS | 1 genes |
| dipeptidyl-peptidase III activity, IEA | 1 genes |
| D-erythro-sphingosine kinase activity, ISS | 1 genes |
| dihydropyrimidine dehydrogenase (NADP+) activity, NAS | 1 genes |
| drug metabolism, NAS | 1 genes |
| DEAD/H-box RNA helicase binding, TAS | 1 genes |
| DNA N-glycosylase activity, IDA | 1 genes |
| deaminase activity, IEA | 1 genes |
| D-ribose catabolism, NAS | 1 genes |
| diacylglycerol binding, ISS | 1 genes |
| diacylglycerol binding, TAS | 1 genes |
| dermatan sulfate biosynthesis, IDA | 1 genes |
| dermatan sulfate biosynthesis, ISS | 1 genes |
| deoxynucleotide transporter activity, TAS | 1 genes |
| deoxynucleotide transport, NAS | 1 genes |
| DNA polymerase processivity factor activity, IEA | 1 genes |
| dendrite, IDA | 1 genes |
| DNA protection, NAS | 1 genes |
| detection of triacylated bacterial lipoprotein, ISS | 1 genes |
| defense response to bacteria, IDA | 1 genes |
| defense response to bacteria, ISS | 1 genes |
| DNA damage response, perception of DNA damage, IDA | 1 genes |
| DNA damage response, signal transduction, IDA | 1 genes |
| defense response to pathogen, NAS | 1 genes |
| defense response to pathogenic protozoa, NAS | 1 genes |
| DNA methylation during embryonic development, NAS | 1 genes |
| DNA methylation during gametogenesis, TAS | 1 genes |
| dynein binding, IDA | 1 genes |
| dynein binding, ISS | 1 genes |
| dUTP metabolism, IEA | 1 genes |
| diacylglycerol metabolism, NAS | 1 genes |
| dimethylglycine dehydrogenase activity, IEA | 1 genes |
| dolichyldiphosphatase activity, ISS | 1 genes |
| delta14-sterol reductase activity, IEA | 1 genes |
| dermatan sulfate proteoglycan biosynthesis, polysaccharide chain biosynthesis, TAS | 1 genes |
| dermatan sulfate proteoglycan metabolism, IDA | 1 genes |
| defense response to Gram-negative bacteria, TAS | 1 genes |
| dihydrobiopterin metabolism, TAS | 1 genes |
AS3D Human
