| calcium ion binding, IEA | 461 genes |
| cellular_component unknown, ND | 418 genes |
| cytoplasm, TAS | 274 genes |
| CD2, T-cell surface antigen CD2 protein. This family consists of several mammalian T-cell surface antigen CD2 proteins as well as homologous African swine fever virus sequences. CD2 mediates T cell adhesion via its ectodomain and signal transd | 267 genes |
| cell adhesion, IEA | 219 genes |
| cell-cell signaling, TAS | 195 genes |
| cell growth and/or maintenance, IEA | 186 genes |
| cell proliferation, TAS | 171 genes |
| Caldesmon, Caldesmon | 151 genes |
| cytoskeleton, IEA | 150 genes |
| cytoplasm, IEA | 149 genes |
| catalytic activity, IEA | 144 genes |
| cation transport, IEA | 142 genes |
| C2, C2 domain | 120 genes |
| cell adhesion, TAS | 120 genes |
| Cadherin, Cadherin domain | 119 genes |
| cell cycle, IEA | 106 genes |
| carbohydrate metabolism, IEA | 104 genes |
| cytoplasm, NAS | 103 genes |
| CobT, Cobalamin biosynthesis protein CobT. This family consists of several bacterial cobalamin biosynthesis (CobT) proteins. CobT is involved in the transformation of precorrin-3 into cobyrinic acid | 96 genes |
| chymotrypsin activity, IEA | 92 genes |
| cell surface receptor linked signal transduction, TAS | 91 genes |
| Candida_ALS, Candida agglutinin-like protein (ALS). This family consists of several agglutinin-like proteins from different Candida species. ALS genes of Candida albicans encode a family of cell-surface glycoproteins with a three-domain struct | 76 genes |
| chemotaxis, TAS | 74 genes |
| calmodulin binding, IEA | 73 genes |
| cytoplasm, NR | 69 genes |
| CH, Calponin homology (CH) domain. The CH domain is found in both cytoskeletal proteins and signal transduction proteins. The CH domain is involved in actin binding in some members of the family. However in calponins there is evidence that the | 68 genes |
| CAP, CAP protein | 68 genes |
| cell motility, TAS | 66 genes |
| chaperone activity, IEA | 63 genes |
| calcium ion binding, TAS | 62 genes |
| cell-cell signaling, NR | 58 genes |
| Collagen, Collagen triple helix repeat (20 copies). Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contai | 54 genes |
| cytosol, TAS | 54 genes |
| central nervous system development, TAS | 54 genes |
| CUB, CUB domain | 53 genes |
| cellular defense response, TAS | 53 genes |
| cell differentiation, IEA | 50 genes |
| cytoplasm, IDA | 48 genes |
| chromosome, IEA | 47 genes |
| cytokine activity, IEA | 46 genes |
| cell growth and/or maintenance, TAS | 45 genes |
| Cytadhesin_P30, Cytadhesin P30/P32. This family consists of several Mycoplasma species specific Cytadhesin P32 and P30 proteins. P30 has been found to be membrane associated and localised on the tip organelle. It is thought that it is importan | 43 genes |
| chromatin, IEA | 43 genes |
| carbohydrate metabolism, TAS | 42 genes |
| cation channel activity, IEA | 41 genes |
| cytoskeleton, TAS | 41 genes |
| cell cycle arrest, TAS | 40 genes |
| chemokine activity, TAS | 40 genes |
| cysteine-type endopeptidase activity, IEA | 37 genes |
| calcium ion transport, IEA | 37 genes |
| chloride transport, IEA | 37 genes |
| calcium ion binding, NAS | 36 genes |
| circulation, TAS | 36 genes |
| cNMP_binding, Cyclic nucleotide-binding domain | 35 genes |
| cell motility, NR | 35 genes |
| chromosome organization and biogenesis (sensu Eukarya), IEA | 35 genes |
| cytosolic calcium ion concentration elevation, TAS | 34 genes |
| C1q, C1q domain. C1q is a subunit of the C1 enzyme complex that activates the serum complement system | 32 genes |
| cytoplasm, ISS | 32 genes |
| coated pit, IEA | 31 genes |
| Cyclin_N, Cyclin, N-terminal domain. Cyclins regulate cyclin dependent kinases (CDKs). One member is a Uracil-DNA glycosylase, which is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, this family corresponds to | 28 genes |
| cytosolic large ribosomal subunit (sensu Eukarya), TAS | 28 genes |
| cell adhesion, NR | 26 genes |
| cell-matrix adhesion, IEA | 26 genes |
| chaperone activity, TAS | 25 genes |
| chromatin assembly/disassembly, IEA | 25 genes |
| chemotaxis, IEA | 25 genes |
| complement activation, classical pathway, IEA | 25 genes |
| cytoskeleton organization and biogenesis, IEA | 25 genes |
| chromatin modification, IEA | 25 genes |
| cytosol, NAS | 24 genes |
| Carb_anhydrase, Eukaryotic-type carbonic anhydrase | 23 genes |
| chromatin binding, IEA | 23 genes |
| COesterase, Carboxylesterase | 22 genes |
| cytosol, NR | 22 genes |
| cell proliferation, IEA | 22 genes |
| cell proliferation, NAS | 22 genes |
| Cpn60_TCP1, TCP-1/cpn60 chaperonin family. This family includes members from the HSP60 chaperone family and the TCP-1 (T-complex protein) family | 21 genes |
| Cadherin_C, Cadherin cytoplasmic region. Cadherins are vital in cell-cell adhesion during tissue differentiation. Cadherins are linked to the cytoskeleton by catenins. Catenins bind to the cytoplasmic tail of the cadherin. Cadherins cluster to | 21 genes |
| cytoskeleton, NR | 21 genes |
| cell-cell adhesion, NAS | 21 genes |
| Connexin, Connexin | 20 genes |
| Cystatin, Cystatin domain. Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. Domains descr | 20 genes |
| CBFD_NFYB_HMF, Histone-like transcription factor (CBF/NF-Y) and archaeal histone. This family includes archaebacterial histones and histone like transcription factors from eukaryotes | 20 genes |
| carboxypeptidase A activity, IEA | 20 genes |
| copper ion binding, IEA | 20 genes |
| Chromo, 'chromo' (CHRromatin Organisation MOdifier) domain | 19 genes |
| collagen, IEA | 19 genes |
| clathrin vesicle coat, IEA | 19 genes |
| cytosolic small ribosomal subunit (sensu Eukarya), TAS | 18 genes |
| cytoskeleton organization and biogenesis, NAS | 18 genes |
| cytoskeletal protein binding, IEA | 18 genes |
| cysteine-type peptidase activity, IEA | 18 genes |
| CARD, Caspase recruitment domain. Motif contained in proteins involved in apoptotic signaling. Predicted to possess a DEATH (pfam00531) domain-like fold | 17 genes |
| cytosol, IDA | 17 genes |
| calcium ion homeostasis, TAS | 17 genes |
| chromosome organization and biogenesis (sensu Eukarya), NAS | 17 genes |
| cell adhesion, NAS | 17 genes |
| cell-matrix adhesion, TAS | 17 genes |
| cation transporter activity, IEA | 17 genes |
| cell differentiation, NAS | 17 genes |
| Cation_ATPase_N, Cation transporter/ATPase, N-terminus. Members of this families are involved in Na+/K+, H+/K+, Ca++ and Mg++ transport | 16 genes |
| carboxypeptidase activity, IEA | 16 genes |
| cysteine-type endopeptidase activity, TAS | 16 genes |
| carbohydrate metabolism, NR | 16 genes |
| cholesterol biosynthesis, IEA | 16 genes |
| collagen catabolism, IEA | 16 genes |
| Cyt-b5, Cytochrome b5-like Heme/Steroid binding domain. This family includes heme binding domains from a diverse range of proteins. This family also includes proteins that bind to steroids. The family includes progesterone receptors. Many memb | 15 genes |
| Cation_ATPase_C, Cation transporting ATPase, C-terminus. Members of this families are involved in Na+/K+, H+/K+, Ca++ and Mg++ transport | 15 genes |
| CD34_antigen, CD34 antigen protein. This family consists of several mammalian CD34 antigen proteins. The CD34 antigen is a human leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. CD34 is a phosphoprotei | 15 genes |
| chromosome organization and biogenesis (sensu Eukarya), TAS | 15 genes |
| cholesterol metabolism, IEA | 15 genes |
| carbohydrate transport, IEA | 15 genes |
| C-C chemokine receptor activity, IEA | 15 genes |
| Crystall, Beta/Gamma crystallin. The alignment comprises two Greek key motifs since the similarity between them is very low | 14 genes |
| CNH, CNH domain. Domain found in NIK1-like kinase, mouse citron and yeast ROM1, ROM2. Unpublished observations | 14 genes |
| CD20, CD20/IgE Fc receptor beta subunit family. This family includes the CD20 protein and the beta subunit of the high affinity receptor for IgE Fc. The high affinity receptor for IgE is a tetrameric structure consisting of a single IgE-bindin | 14 genes |
| Chon_Sulph_att, Chondroitin sulphate attachment domain. This family represents the chondroitin sulphate attachment domain of vertebrate neural transmembrane proteoglycans that contain EGF modules. Evidence has been accumulated to support the i | 14 genes |
| centrosome, TAS | 14 genes |
| cytosol, ISS | 14 genes |
| connexon complex, IEA | 14 genes |
| cell communication, IEA | 14 genes |
| cell surface receptor linked signal transduction, NAS | 14 genes |
| calcium-dependent cell-cell adhesion, NAS | 14 genes |
| Clat_adaptor_s, Clathrin adaptor complex small chain | 13 genes |
| cellular morphogenesis, IEA | 13 genes |
| carbonate dehydratase activity, TAS | 13 genes |
| calmodulin binding, NAS | 13 genes |
| cell cycle, TAS | 13 genes |
| cell surface receptor linked signal transduction, NR | 13 genes |
| cell-cell signaling, NAS | 13 genes |
| connexon channel activity, IEA | 13 genes |
| cell growth, NAS | 13 genes |
| CRAL_TRIO, CRAL/TRIO domain. The original profile has been extended to include the carboxyl domain from the known structure of Sec14 | 12 genes |
| Cyclin_C, Cyclin, C-terminal domain. Cyclins regulate cyclin dependent kinases (CDKs). One member is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresp | 12 genes |
| cysteine protease inhibitor activity, IEA | 12 genes |
| cytokine activity, TAS | 12 genes |
| calmodulin binding, TAS | 12 genes |
| cytoskeleton, NAS | 12 genes |
| calcium ion transport, TAS | 12 genes |
| cell cycle arrest, IEA | 12 genes |
| chromosome segregation, IEA | 12 genes |
| cholesterol metabolism, TAS | 12 genes |
| cell proliferation, NR | 12 genes |
| cytolysis, IEA | 12 genes |
| Cys_knot, Cystine-knot domain. The family comprises glycoprotein hormones and the C-terminal domain of various extracellular proteins. It is believed to be involved in disulfide-linked dimerisation | 11 genes |
| CBS, CBS domain. CBS domains are small intracellular modules of unknown function. They are mostly found in 2 or four copies within a protein. Pairs of CBS domains dimerise to form a stable globular domain. Two CBS domains are found in inosine- | 11 genes |
| Calpain_III, Calpain large subunit, domain III. The function of the domain III and I are currently unknown. Domain II is a cysteine protease and domain IV is a calcium binding domain. Calpains are believed to participate in intracellular signa | 11 genes |
| COLFI, Fibrillar collagen C-terminal domain. Found at C-termini of fibrillar collagens: Ephydatia muelleri procollagen EMF1 alpha, vertebrate collagens alpha(1)III, alpha(1)II, alpha(2)V etc | 11 genes |
| Cation_efflux, Cation efflux family. Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remov | 11 genes |
| CRAL_TRIO_N, CRAL/TRIO, N-terminus. This all-alpha domain is found to the N-terminus of pfam00650 | 11 genes |
| CENP-B_N, CENP-B N-terminal DNA-binding domain. Centromere Protein B (CENP-B) is a DNA-binding protein localised to the centromere. Within the N-terminal 125 residues, there is a DNA-binding region, which binds to a corresponding 17bp CENP-B b | 11 genes |
| CITED, CITED. CITED, CBP/p300-interacting transactivator with ED-rich tail, are characterized by a conserved 32-amino acid sequence at the C-terminus. CITED proteins do not bind DNA directly and are thought to function as transcriptional co-ac | 11 genes |
| chromatin binding, TAS | 11 genes |
| chaperone activity, NAS | 11 genes |
| cytochrome-c oxidase activity, TAS | 11 genes |
| cytosol, IEA | 11 genes |
| complement activation, alternative pathway, IEA | 11 genes |
| cytoskeleton organization and biogenesis, TAS | 11 genes |
| Cofilin_ADF, Cofilin/tropomyosin-type actin-binding protein. Severs actin filaments and binds to actin monomers | 10 genes |
| CAP_GLY, CAP-Gly domain. Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in | 10 genes |
| CDC45, CDC45-like protein. CDC45 is an essential gene required for initiation of DNA replication in S. cerevisiae, forming a complex with MCM5/CDC46. Homologues of CDC45 have been identified in human, mouse and smut fungus, amongst others | 10 genes |
| CHGN, Chondroitin N-acetylgalactosaminyltransferase | 10 genes |
| Cripto, Cripto growth factor. This family consists of several eukaryotic cripto growth factor related proteins. Within a multicellular organism, communication between cells is essential during development to ensure proper execution of cell mig | 10 genes |
| CTP biosynthesis, IEA | 10 genes |
| C21-steroid hormone biosynthesis, IEA | 10 genes |
| calcium ion transport, NAS | 10 genes |
| cell cycle, NAS | 10 genes |
| circadian rhythm, TAS | 10 genes |
| carbohydrate biosynthesis, IEA | 10 genes |
| cell wall catabolism, IEA | 10 genes |
| CSD, 'Cold-shock' DNA-binding domain | 9 genes |
| Cullin, Cullin family | 9 genes |
| Corona_nucleoca, Coronavirus nucleocapsid protein | 9 genes |
| Coprinus_mating, Coprinus cinereus mating-type protein. This family consists of several mating-type alpha and beta proteins from Coprinus cinereus (Inky cap fungus) as well as a related sequence from Schizophyllum commune (Bracket fungus). The | 9 genes |
| Copine, Copine. This family represents a conserved region approximately 180 residues long within eukaryotic copines. Copines are Ca(2+)-dependent phospholipid-binding proteins that are thought to be involved in membrane-trafficking, and may al | 9 genes |
| chromatin, TAS | 9 genes |
| cytochrome-c oxidase activity, IEA | 9 genes |
| cytokine activity, NAS | 9 genes |
| calcium ion binding, ISS | 9 genes |
| calcium ion binding, NR | 9 genes |
| cGMP biosynthesis, IEA | 9 genes |
| cell-matrix adhesion, NAS | 9 genes |
| cell surface receptor linked signal transduction, IEA | 9 genes |
| cell growth and/or maintenance, NAS | 9 genes |
| cAMP-dependent protein kinase regulator activity, IEA | 9 genes |
| cell surface, IDA | 9 genes |
| channel or pore class transporter activity, TAS | 9 genes |
| CN_hydrolase, Carbon-nitrogen hydrolase. This family contains hydrolases that break carbon-nitrogen bonds. The family includes: Nitrilase EC:3.5.5.1, Aliphatic amidase EC:3.5.1.4, Biotidinase EC:3.5.1.12, Beta-ureidopropionase EC:3.5.1.6 | 8 genes |
| CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain. Carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl-phosphate from glutamine or ammonia and bicarbonate. This important enzyme initiates both the | 8 genes |
| Calx-beta, Calx-beta domain | 8 genes |
| CHCH, CHCH domain. we have identified a conserved motif in the LOC118487 protein that we have called the CHCH motif. Alignment of this protein with related members showed the presence of three subgroups of proteins, which are called the S (Sma | 8 genes |
| cell cycle checkpoint, TAS | 8 genes |
| cyclin-dependent protein kinase activity, TAS | 8 genes |
| copper ion binding, NAS | 8 genes |
| calcium-dependent phospholipid binding, IEA | 8 genes |
| chromatin remodeling, NAS | 8 genes |
| catecholamine metabolism, IEA | 8 genes |
| cellular defense response, NR | 8 genes |
| circulation, NR | 8 genes |
| cell proliferation, ISS | 8 genes |
| coreceptor activity, TAS | 8 genes |
| chromatin modification, TAS | 8 genes |
| clathrin coat of trans-Golgi network vesicle, IEA | 8 genes |
| CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain. Carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl-phosphate from glutamine or ammonia and bicarbonate. This important enzyme initiates both t | 7 genes |
| Carn_acyltransf, Choline/Carnitine o-acyltransferase | 7 genes |
| CTF_NFI, CTF/NF-I family transcription modulation region | 7 genes |
| CTP_transf_2, Cytidylyltransferase. This family includes: Cholinephosphate cytidylyltransferase, Glycerol-3-phosphate cytidylyltransferase | 7 genes |
| CUT, CUT domain. The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein | 7 genes |
| CUE, CUE domain. CUE domains have been shown to bind ubiquitin. It has been suggested that CUE domains are related to pfam00627. CUE domains also occur in two protein of the IL-1 signal transduction pathway, tollip and TAB2 | 7 genes |
| CBM_21, Putative phosphatase regulatory subunit. This family consists of several eukaryotic proteins that are thought to be involved in the regulation of glycogen metabolism. For instance, the mouse PTG protein has been shown to interact with | 7 genes |
| CD225, Interferon-induced transmembrane protein. This family includes the human leukocyte antigen CD225, which is an interferon inducible transmembrane protein, and is associated with interferon induced cell growth suppression | 7 genes |
| CHL4, CHL4 family. This family includes CHL4 that is involved in chromosome segregation | 7 genes |
| Complex1_LYR, Complex 1 protein (LYR family). This family of short proteins includes proteins from the NADH-ubiquinone oxidoreductase complex I. The family includes the B14 subunit from Cow, and the B22 subunit from human. We would predict tha | 7 genes |
| chromosome, telomeric region, IEA | 7 genes |
| cytokinesis, NAS | 7 genes |
| cytokinesis, TAS | 7 genes |
| calpain activity, TAS | 7 genes |
| cyclin-dependent protein kinase inhibitor activity, TAS | 7 genes |
| cysteine protease inhibitor activity, TAS | 7 genes |
| calcium channel activity, IEA | 7 genes |
| calcium-transporting ATPase activity, TAS | 7 genes |
| collagen binding, TAS | 7 genes |
| cytoplasm, IC | 7 genes |
| cAMP biosynthesis, IEA | 7 genes |
| caspase activation, NAS | 7 genes |
| central nervous system development, NAS | 7 genes |
| chemokine activity, IEA | 7 genes |
| caspase activator activity, NAS | 7 genes |
| caspase activity, TAS | 7 genes |
| Calponin, Calponin family repeat | 6 genes |
| CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. All of these members have the ability to catalyse the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond and concomitant breaking of a phosph | 6 genes |
| Calsequestrin, Calsequestrin | 6 genes |
| C4, C-terminal tandem repeated domain in type 4 procollagen. Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome | 6 genes |
| Cons_hypoth95, Conserved hypothetical protein 95 | 6 genes |
| CP2, CP2 transcription factor. This family represents a conserved region in the CP2 transcription factor family | 6 genes |
| CS, CS domain. The role of the CS domain is unclear. The CS and CHORD (pfam04968) are fused into a single polypeptide chain in metazoans but are found in separate proteins in plants is is thought to be indicative of an interaction between CS a | 6 genes |
| chromosome, pericentric region, IEA | 6 genes |
| chaperone activity, NR | 6 genes |
| cAMP-specific phosphodiesterase activity, TAS | 6 genes |
| copper, zinc superoxide dismutase activity, IEA | 6 genes |
| copper ion binding, TAS | 6 genes |
| calcium ion storage activity, IEA | 6 genes |
| calmodulin binding, ISS | 6 genes |
| chromatin assembly complex, TAS | 6 genes |
| cytoplasm, IEP | 6 genes |
| cAMP-dependent protein kinase complex, IEA | 6 genes |
| chromatin remodeling, TAS | 6 genes |
| cotranslational membrane targeting, TAS | 6 genes |
| copper ion transport, TAS | 6 genes |
| cell communication, NAS | 6 genes |
| cell-cell signaling, IEA | 6 genes |
| cell death, TAS | 6 genes |
| connexon channel activity, TAS | 6 genes |
| cyclosporin A binding, TAS | 6 genes |
| cell growth, IEA | 6 genes |
| cell-cell adhesion, IEA | 6 genes |
| calcium-mediated signaling, ISS | 6 genes |
| caspase activity, IEA | 6 genes |
| Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme. This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase | 5 genes |
| CIDE-N, CIDE-N domain. This domain is found in CAD nuclease, ICAD the inhibitor of CAD nuclease. The two proteins interact through this domain | 5 genes |
| Cornifin, Cornifin (SPRR) family. SPRR genes (formerly SPR) encode a novel class of polypeptides (small proline rich proteins) that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo.The most char | 5 genes |
| cobW, Cobalamin synthesis protein/P47K. This family of proteins contains P47K, a Pseudomonas chlororaphis protein needed for nitrile hydratase expression, and the cobW gene product, which may be involved in cobalamin biosynthesis in Pseudomona | 5 genes |
| Cache, Cache domain | 5 genes |
| Cytochrom_B561, Cytochrome b561 | 5 genes |
| CDK5_activator, Cyclin-dependent kinase 5 activator protein | 5 genes |
| CAF1, CAF1 family ribonuclease. The major pathways of mRNA turnover in eukaryotes initiate with shortening of the polyA tail. CAF1 encodes a critical component of the major cytoplasmic deadenylase in yeast. Both Caf1p is required for normal mR | 5 genes |
| Chromadorea_ALT, Chromadorea ALT protein. This family consists of several ALT protein homologues found in nematodes. Lymphatic filariasis is a major tropical disease caused by the mosquito borne nematodes Brugia and Wuchereria. About 120 milli | 5 genes |
| chromatin binding, ISS | 5 genes |
| chromatin binding, NAS | 5 genes |
| cGMP-specific phosphodiesterase activity, TAS | 5 genes |
| chemokine receptor activity, TAS | 5 genes |
| cytokine activity, NR | 5 genes |
| calcium channel activity, TAS | 5 genes |
| carrier activity, IEA | 5 genes |
| chromatin silencing complex, IEA | 5 genes |
| cell-cell signaling, IC | 5 genes |
| central nervous system development, ISS | 5 genes |
| chemosensory behavior, TAS | 5 genes |
| calcium sensitive guanylate cyclase activator activity, TAS | 5 genes |
| coreceptor activity, NAS | 5 genes |
| cell migration, NAS | 5 genes |
| chromatin modification, NAS | 5 genes |
| COPII vesicle coat, IEA | 5 genes |
| cell differentiation, ISS | 5 genes |
| collagen fibril organization, NAS | 5 genes |
| catecholamine biosynthesis, IEA | 5 genes |
| Calreticulin, Calreticulin family | 4 genes |
| Clathrin, Region in Clathrin and VPS. Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain | 4 genes |
| Ca_channel_B, Dihydropyridine sensitive L-type calcium channel (Beta subunit) | 4 genes |
| Carboxyl_trans, Carboxyl transferase domain. All of the members in this family are biotin dependent carboxylases. The carboxyl transferase domain carries out the following reaction; transcarboxylation from biotin to an acceptor molecule. There | 4 genes |
| Chromo_shadow, Chromo shadow domain. This domain is distantly related to pfam00385. This domain is always found in association with a chromo domain | 4 genes |
| CorA, CorA-like Mg2+ transporter protein. The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli. CorA is virtually ubiquitous in the Bacteria and Archaea. There are also eukaryotic relatives | 4 genes |
| Choline_kinase, Choline/ethanolamine kinase. Choline kinase catalyses the committed step in the synthesis of phosphatidylcholine by the CDP-choline pathway | 4 genes |
| COX7a, Cytochrome c oxidase subunit VIIa. Cytochrome c oxidase, a 13 sub-unit complex, is the terminal oxidase in the mitochondrial electron transport chain. This family is composed of the heart and liver isoforms of cytochrome c oxidase subun | 4 genes |
| CaMBD, Calmodulin binding domain. Small-conductance Ca2+-activated K+ channels (SK channels) are independent of voltage and gated solely by intracellular Ca2+. These membrane channels are heteromeric complexes that comprise pore-forming alpha- | 4 genes |
| Chitin_synth_2, Chitin synthase. Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They catalyse chitin synthesis as follows: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N) <=> UDP + {(1,4)-(N-acety | 4 genes |
| CaKB, Calcium-activated potassium channel, beta subunit | 4 genes |
| Cornichon, Cornichon protein | 4 genes |
| Caudal_act, Caudal like protein activation region. This family consists of the amino termini of proteins belonging to the caudal-related homeobox protein family. This region is thought to mediate transcription activation. The level of activati | 4 genes |
| Calcipressin, Calcipressin. Calcipressin is also known as calcineurin-binding protein, since it inhibits calcineurin-mediated transcriptional modulation by binding to calcineurin's catalytic domain | 4 genes |
| CNPase, 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase). This family consists of the eukaryotic protein 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP). 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) is one of the earliest | 4 genes |
| condensed nuclear chromosome, TAS | 4 genes |
| cartilage condensation, TAS | 4 genes |
| cell fate determination, NAS | 4 genes |
| chaperone activity, ISS | 4 genes |
| carbonate dehydratase activity, IEA | 4 genes |
| creatine kinase activity, TAS | 4 genes |
| cytochrome-b5 reductase activity, TAS | 4 genes |
| casein kinase I activity, TAS | 4 genes |
| calcium- and calmodulin-dependent protein kinase activity, IDA | 4 genes |
| calcium- and calmodulin-dependent protein kinase activity, TAS | 4 genes |
| cAMP-dependent protein kinase activity, NAS | 4 genes |
| cAMP-dependent protein kinase activity, TAS | 4 genes |
| carrier activity, TAS | 4 genes |
| calcium-transporting ATPase activity, IEA | 4 genes |
| cytoplasmic dynein complex, NAS | 4 genes |
| connexon complex, TAS | 4 genes |
| cAMP-dependent protein kinase complex, NAS | 4 genes |
| chromatin remodeling, NR | 4 genes |
| chromatin silencing, IEA | 4 genes |
| ceramide metabolism, TAS | 4 genes |
| cation transport, NAS | 4 genes |
| cation transport, TAS | 4 genes |
| caspase activation, TAS | 4 genes |
| cell motility, NAS | 4 genes |
| cytoskeleton organization and biogenesis, ISS | 4 genes |
| cytoskeletal anchoring, TAS | 4 genes |
| cytosolic calcium ion concentration elevation, IDA | 4 genes |
| cell recognition, TAS | 4 genes |
| cytoskeletal protein binding, TAS | 4 genes |
| cytoskeletal adaptor activity, NAS | 4 genes |
| cell death, IEA | 4 genes |
| cysteine-type peptidase activity, TAS | 4 genes |
| cell proliferation, IDA | 4 genes |
| cholesterol binding, IEA | 4 genes |
| coenzyme A biosynthesis, IEA | 4 genes |
| carbon utilization by fixation of carbon dioxide, IEA | 4 genes |
| cell growth, ISS | 4 genes |
| carboxy-lyase activity, IEA | 4 genes |
| cholesterol transporter activity, IEA | 4 genes |
| COPII vesicle coat, NAS | 4 genes |
| cell differentiation, TAS | 4 genes |
| cortical actin cytoskeleton organization and biogenesis, IEA | 4 genes |
| cytoplasmic sequestering of transcription factor, TAS | 4 genes |
| cadmium ion binding, NAS | 4 genes |
| Calc_CGRP_IAPP, Calcitonin / CGRP / IAPP family | 3 genes |
| Crystallin, Alpha crystallin A chain, N terminal | 3 genes |
| CBM_20, Starch binding domain | 3 genes |
| Cu2_monooxygen, Copper type II ascorbate-dependent monooxygenase, N-terminal domain. The N and C-terminal domains of members of this family adopt the same PNGase F-like fold | 3 genes |
| Cobalamin_bind, Eukaryotic cobalamin-binding protein | 3 genes |
| CD36, CD36 family. The CD36 family is thought to be a novel class of scavenger receptors. There is also evidence suggesting a possible role in signal transduction. CD36 is involved in cell adhesion | 3 genes |
| Caveolin, Caveolin | 3 genes |
| CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kina | 3 genes |
| Cu_amine_oxid, Copper amine oxidase, enzyme domain. Copper amine oxidases are a ubiquitous and novel group of quinoenzymes that catalyse the oxidative deamination of primary amines to the corresponding aldehydes, with concomitant reduction of | 3 genes |
| CBM_14, Chitin binding Peritrophin-A domain. This domain is called the Peritrophin-A domain and is found in chitin binding proteins particularly peritrophic matrix proteins of insects and animal chitinases. Copies of the domain are also found | 3 genes |
| COX6A, Cytochrome c oxidase subunit VIa | 3 genes |
| CDI, Cyclin-dependent kinase inhibitor. Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (CDIs). CDIs are involved in cell cycle arrest at the G1 phase | 3 genes |
| Cbl_N, CBL proto-oncogene N-terminal domain 1. Cbl is an adaptor protein that binds EGF receptors (or other tyrosine kinases) and SH3 domains, functioning as a negative regulator of many signaling pathways. The N-terminal domain is evolutionar | 3 genes |
| COX6B, Cytochrome oxidase c subunit VIb. Cytochrome c oxidase, a 13 sub-unit complex, EC:1.9.3.1 is the terminal oxidase in the mitochondrial electron transport chain. This family is composed of the potentially heme-binding subunit IVb of the | 3 genes |
| Cu_amine_oxidN2, Copper amine oxidase, N2 domain. This domain is the first or second structural domain in copper amine oxidases, it is known as the N2 domain. Its function is uncertain. The catalytic domain can be found in pfam01179. Copper am | 3 genes |
| Cu_amine_oxidN3, Copper amine oxidase, N3 domain. This domain is the second or third structural domain in copper amine oxidases, it is known as the N3 domain. Its function is uncertain. The catalytic domain can be found in pfam01179. Copper am | 3 genes |
| Cbl_N2, CBL proto-oncogene N-terminus, EF hand-like domain. Cbl is an adaptor protein that binds EGF receptors (or other tyrosine kinases) and SH3 domains, functioning as a negative regulator of many signaling pathways. The N-terminal domain i | 3 genes |
| Cbl_N3, CBL proto-oncogene N-terminus, SH2-like domain. Cbl is an adaptor protein that binds EGF receptors (or other tyrosine kinases) and SH3 domains, functioning as a negative regulator of many signaling pathways. The N-terminal domain is ev | 3 genes |
| COX4, Cytochrome c oxidase subunit IV. Cytochrome c oxidase, a 13 sub-unit complex, EC:1.9.3.1 is the terminal oxidase in the mitochondrial electron transport chain. This family is composed of cytochrome c oxidase subunit IV. The Dictyostelium | 3 genes |
| CPSF_A, CPSF A subunit region. This family includes a region that lies towards the C-terminus of the cleavage and polyadenylation specificity factor (CPSF) A (160 kDa) subunit. CPSF is involved in mRNA polyadenylation and binds the AAUAAA cons | 3 genes |
| CDC37, Cdc37 family. In the budding yeast Saccharomyces cerevisiae, Cdc37 is required for the productive formation of Cdc28-cyclin complexes. Cdc37 may be a kinase targeting subunit of Hsp90 | 3 genes |
| Cu2_monoox_C, Copper type II ascorbate-dependent monooxygenase, C-terminal domain. The N and C-terminal domains of members of this family adopt the same PNGase F-like fold | 3 genes |
| CBF, CBF/Mak21 family | 3 genes |
| CD47, CD47 integrin associated protein. This family represents the CD47 leukocyte antigen | 3 genes |
| Cnd1, Non-SMC condensin subunit, XCAP-D2/Cnd1. Condensin is a multi-subunit protein complex that acts as an essential regulator of chromosome condensation. It contains both SMC (structural maintenance of chromosomes) and non-SMC subunits. This | 3 genes |
| Cor1, Cor1/Xlr/Xmr conserved region. Cor1 is a component of the chromosome core in the meiotic prophase chromosomes. Xlr is a lymphoid cell specific protein. Xlm is abundantly transcribed in testis in a tissue-specific and developmentally regu | 3 genes |
| Cwf_Cwc_15, Cwf15/Cwc15 cell cycle control protein. This family represents Cwf15/Cwc15 (from Schizosaccharomyces pombe and Saccharomyces cerevisiae respectively) and their homologues. The function of these proteins is unknown, but they form pa | 3 genes |
| CHORD, CHORD. CHORD represents a Zn binding domain. Silencing of the C. elegans CHORD-containing gene results in semisterility and embryo lethality, suggesting an essential function of the wild-type gene in nematode development | 3 genes |
| Complex1_17_2kD, NADH:ubiquinone oxidoreductase 17.2 kD subunit. This family contains the 17.2 kD subunit of complex I and its homologues. The family also contains a second related eukaryotic protein of unknown function | 3 genes |
| Calsarcin, Calcineurin-binding protein (Calsarcin). This family consists of several mammalian calcineurin-binding proteins. The calcium- and calmodulin-dependent protein phosphatase calcineurin has been implicated in the transduction of signal | 3 genes |
| Calcyon, D1 dopamine receptor-interacting protein (calcyon). This family consists of several D1 dopamine receptor-interacting (calcyon) proteins. D1/D5 dopamine receptors in the basal ganglia, hippocampus, and cerebral cortex modulate motor, r | 3 genes |
| COG6, Conserved oligomeric complex COG6. COG6 is a component of the conserved oligomeric golgi complex, which is composed of eight different subunits and is required for normal golgi morphology and localisation | 3 genes |
| Clp1, Pre-mRNA cleavage complex II protein Clp1. This family consists of several pre-mRNA cleavage complex II Clp1 (or HeaB) proteins. Six different protein factors are required in vitro for 3' end formation of mammalian pre-mRNAs by endonucle | 3 genes |
| chromosome, pericentric region, TAS | 3 genes |
| chromosome, telomeric region, IC | 3 genes |
| chromatin, NR | 3 genes |
| condensed nuclear chromosome, ISS | 3 genes |
| cartilage condensation, NR | 3 genes |
| ciliary/flagellar motility, IEA | 3 genes |
| co-chaperonin activity, TAS | 3 genes |
| calmodulin-dependent cyclic-nucleotide phosphodiesterase activity, TAS | 3 genes |
| cytidine deaminase activity, TAS | 3 genes |
| carboxypeptidase A activity, TAS | 3 genes |
| calpain activity, IEA | 3 genes |
| calcium- and calmodulin-dependent protein kinase activity, ISS | 3 genes |
| cytokine activity, ISS | 3 genes |
| calcium channel regulator activity, TAS | 3 genes |
| copper ion transporter activity, TAS | 3 genes |
| calcium:sodium antiporter activity, IEA | 3 genes |
| calcium ion binding, IDA | 3 genes |
| calcium ion sensing, TAS | 3 genes |
| collagen binding, NAS | 3 genes |
| calcium-dependent phospholipid binding, NAS | 3 genes |
| calcium-dependent phospholipid binding, TAS | 3 genes |
| collagen type I, NR | 3 genes |
| collagen type V, TAS | 3 genes |
| collagen type IX, TAS | 3 genes |
| centrosome, IDA | 3 genes |
| cytosol, IEP | 3 genes |
| cytosolic large ribosomal subunit (sensu Eukarya), NR | 3 genes |
| cytoplasmic dynein complex, TAS | 3 genes |
| cAMP biosynthesis, NAS | 3 genes |
| cholesterol biosynthesis, TAS | 3 genes |
| calcium ion transport, IDA | 3 genes |
| calcium ion transport, NR | 3 genes |
| cobalt ion transport, IEA | 3 genes |
| calcium ion homeostasis, NAS | 3 genes |
| copper ion homeostasis, TAS | 3 genes |
| chemotaxis, NR | 3 genes |
| cytoskeleton organization and biogenesis, NR | 3 genes |
| cytoskeletal anchoring, NR | 3 genes |
| cell cycle arrest, IDA | 3 genes |
| cell cycle arrest, ISS | 3 genes |
| chromosome segregation, TAS | 3 genes |
| cell communication, TAS | 3 genes |
| cell adhesion, IDA | 3 genes |
| cell adhesion, ISS | 3 genes |
| cell surface receptor linked signal transduction, ISS | 3 genes |
| cytosolic calcium ion concentration elevation, IGI | 3 genes |
| cytosolic calcium ion concentration elevation, ISS | 3 genes |
| cytoplasmic sequestering of NF-kappaB, NAS | 3 genes |
| cell recognition, NAS | 3 genes |
| cyclin catabolism, TAS | 3 genes |
| chitin binding, IEA | 3 genes |
| cytoskeletal adaptor activity, TAS | 3 genes |
| collagenase activity, TAS | 3 genes |
| cell growth and/or maintenance, NR | 3 genes |
| cholesterol metabolism, NAS | 3 genes |
| cell death, NAS | 3 genes |
| cell death, NR | 3 genes |
| cytochrome c oxidase biogenesis, TAS | 3 genes |
| cAMP-dependent protein kinase regulator activity, TAS | 3 genes |
| cyclic nucleotide metabolism, NAS | 3 genes |
| cobalt ion transporter activity, IEA | 3 genes |
| calcium-release channel activity, TAS | 3 genes |
| cytoplasmic vesicle, TAS | 3 genes |
| cell growth, IDA | 3 genes |
| carotenoid biosynthesis, IEA | 3 genes |
| C-X-C chemokine receptor activity, IEA | 3 genes |
| caveolar membrane, IEA | 3 genes |
| cytokine and chemokine mediated signaling pathway, IDA | 3 genes |
| calcium-mediated signaling, IEA | 3 genes |
| calcium-mediated signaling, NAS | 3 genes |
| calcium-mediated signaling, TAS | 3 genes |
| cyclic-nucleotide-mediated signaling, ISS | 3 genes |
| caspase inhibitor activity, IDA | 3 genes |
| calcium-dependent phospholipase A2 activity, TAS | 3 genes |
| cofactor binding, IEA | 3 genes |
| Cpn10, Chaperonin 10 Kd subunit | 2 genes |
| Citrate_synt, Citrate synthase | 2 genes |
| Cu-oxidase, Multicopper oxidase. Many of the proteins in this family contain multiple similar copies of this plastocyanin-like domain | 2 genes |
| CRF, Corticotropin-releasing factor family | 2 genes |
| CPSase_sm_chain, Carbamoyl-phosphate synthase small chain, CPSase domain. The carbamoyl-phosphate synthase domain is in the amino terminus of protein. Carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl-phosphate fro | 2 genes |
| Clathrin_lg_ch, Clathrin light chain | 2 genes |
| Clusterin, Clusterin | 2 genes |
| CKS, Cyclin-dependent kinase regulatory subunit | 2 genes |
| CoaE, Dephospho-CoA kinase. This family catalyses the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form Coenzyme A EC:2.7.1.24. This enzyme uses ATP in its reaction | 2 genes |
| CoA_trans, Coenzyme A transferase | 2 genes |
| Clathrin_propel, Clathrin propeller repeat. Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended thr | 2 genes |
| CBAH, Linear amide C-N hydrolases, choloylglycine hydrolase family. This family includes several hydrolases which cleave carbon-nitrogen bonds, other than peptide bonds, in linear amides. These include choloylglycine hydrolase (conjugated bile | 2 genes |
| COX8, Cytochrome oxidase c subunit VIII. Cytochrome c oxidase, a 13 sub-unit complex, EC:1.9.3.1 is the terminal oxidase in the mitochondrial electron transport chain. This family is composed of cytochrome c oxidase subunit VIII | 2 genes |
| CDC48_N, Cell division protein 48 (CDC48), N-terminal domain. This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal function | 2 genes |
| CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria | 2 genes |
| CoA_binding, CoA binding domain. This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases | 2 genes |
| CPSase_L_D3, Carbamoyl-phosphate synthetase large chain, oligomerisation domain. Carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl-phosphate from glutamine or ammonia and bicarbonate. The carbamoyl-phosphate syntha | 2 genes |
| CDC50, LEM3 (ligand-effect modulator 3) family / CDC50 family. Members of this family have been predicted to contain transmembrane helices. The family member LEM3 is a ligand-effect modulator, mutation of which increases glucocorticoid recepto | 2 genes |
| CO_deh_flav_C, CO dehydrogenase flavoprotein C-terminal domain | 2 genes |
| CXC, Tesmin/TSO1-like CXC domain. This family includes proteins that have two copies of a cysteine rich motif as follows: C-X-C-X4-C-X3-YC-X-C-X6-C-X3-C-X-C-X2-C. The family includes Tesmin and TSO1. This family is called a CXC domain in | 2 genes |
| CG-1, CG-1 domain. CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite NLS and named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein. CG- | 2 genes |
| Coatomer_WDAD, Coatomer WD associated region | 2 genes |
| Ctr, Ctr copper transporter family. The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress protection, hormone production, and pigmentation. A widely conser | 2 genes |
| Cnd3_C, Chromosome condensation protein 3, C-terminal region. Cnd3 is a Member of the five subunit condensin complex. Each subunit is essential for mitotic condensation | 2 genes |
| CHD5, CHD5-like protein. Members of this family are probably coiled-coil proteins that are similar to the CHD5 (Congenital heart disease 5) protein. The exact molecular function of these eukaryotic proteins is unknown | 2 genes |
| CwfJ_C_2, Protein similar to CwfJ C-terminus 2. This region is found in the N terminus of Schizosaccharomyces pombe protein CwfJ. CwfJ is part of the Cdc5p complex involved in mRNA splicing | 2 genes |
| CwfJ_C_1, Protein similar to CwfJ C-terminus 1. This region is found in the N terminus of Schizosaccharomyces pombe protein CwfJ. CwfJ is part of the Cdc5p complex involved in mRNA splicing | 2 genes |
| Coatomer_E, Coatomer epsilon subunit. This family represents the epsilon subunit of the coatomer complex, which is involved in the regulation of intracellular protein trafficking between the endoplasmic reticulum and the Golgi complex | 2 genes |
| Cytochrom_B558a, Cytochrome Cytochrome b558 alpha-subunit. Cytochrome b-245 light chain (p22-phox) is one of the key electron transfer elements of the NADPH oxidase in phagocytes | 2 genes |
| CybS, CybS. This family consists of several eukaryotic succinate dehydrogenase [ubiquinone] cytochrome B small subunit, mitochondrial precursor (CybS) proteins. SDHD encodes the small subunit (cybS) of cytochrome b in succinate-ubiquinone oxid | 2 genes |
| COX7B, Cytochrome C oxidase chain VIIB | 2 genes |
| CLPTM1, Cleft lip and palate transmembrane protein 1 (CLPTM1). This family consists of several eukaryotic cleft lip and palate transmembrane protein 1 sequences. Cleft lip with or without cleft palate is a common birth defect that is genetical | 2 genes |
| COG2, COG (conserved oligomeric Golgi) complex component, COG2. The COG complex comprises of eight proteins COG1-8. The COG complex plays critical roles in Golgi structure and function | 2 genes |
| CTP_synth_N, CTP synthase N-terminus. This family consists of the N-terminal region of the CTP synthase protein (EC:6.3.4.2). This family is found in conjunction with pfam00117 located in the C-terminal region of the protein. CTP synthase cata | 2 genes |
| COPI_C, Coatomer (COPI) alpha subunit C-terminus. This family represents the C-terminus (approximately 500 residues) of the eukaryotic coatomer alpha subunit. Coatomer (COPI) is a large cytosolic protein complex which forms a coat around vesic | 2 genes |
| Chlorophyllase, Chlorophyllase. This family consists of several plant specific Chlorophyllase proteins (EC:3.1.1.14). Chlorophyllase (Chlase) is the first enzyme involved in chlorophyll (Chl) degradation and catalyses the hydrolysis of ester b | 2 genes |
| centromere and kinetochore complex maturation, NAS | 2 genes |
| chromosome, pericentric region, NAS | 2 genes |
| cornified envelope, NAS | 2 genes |
| cell glucose homeostasis, ISS | 2 genes |
| cell fate determination, ISS | 2 genes |
| cell fate determination, TAS | 2 genes |
| chromatin binding, IDA | 2 genes |
| chaperone activity, IDA | 2 genes |
| co-chaperone activity, TAS | 2 genes |
| coagulation factor XIa activity, TAS | 2 genes |
| catalytic activity, ISS | 2 genes |
| catalytic activity, NR | 2 genes |
| C-terminal protein carboxyl methyltransferase activity, TAS | 2 genes |
| CTP synthase activity, TAS | 2 genes |
| copper-exporting ATPase activity, TAS | 2 genes |
| carbonyl reductase (NADPH) activity, TAS | 2 genes |
| carnitine O-palmitoyltransferase activity, TAS | 2 genes |
| choline-phosphate cytidylyltransferase activity, TAS | 2 genes |
| cGMP-inhibited cyclic-nucleotide phosphodiesterase activity, TAS | 2 genes |
| carboxypeptidase activity, TAS | 2 genes |
| carboxypeptidase A activity, NAS | 2 genes |
| cathepsin L activity, TAS | 2 genes |
| caspase-activated deoxyribonuclease activity, TAS | 2 genes |
| calcium- and calmodulin-dependent protein kinase activity, NAS | 2 genes |
| cGMP-dependent protein kinase activity, IEA | 2 genes |
| calcium-dependent protein serine/threonine phosphatase activity, NAS | 2 genes |
| cysteine-tRNA ligase activity, IEA | 2 genes |
| cysteine protease inhibitor activity, NR | 2 genes |
| cannabinoid receptor activity, TAS | 2 genes |
| calcium channel regulator activity, NR | 2 genes |
| chloride channel activity, TAS | 2 genes |
| cation channel activity, TAS | 2 genes |
| calcium channel activity, ISS | 2 genes |
| copper ion transporter activity, IEA | 2 genes |
| carrier activity, NAS | 2 genes |
| calcium ion sensing, IDA | 2 genes |
| calmodulin binding, IDA | 2 genes |
| collagen binding, IEA | 2 genes |
| collagen binding, NR | 2 genes |
| calcium-dependent phospholipid binding, NR | 2 genes |
| collagen, NR | 2 genes |
| collagen, TAS | 2 genes |
| collagen type IV, IDA | 2 genes |
| collagen type IV, TAS | 2 genes |
| complement component C1q complex, TAS | 2 genes |
| cell, TAS | 2 genes |
| centrosome, ISS | 2 genes |
| centriole, TAS | 2 genes |
| cytosolic small ribosomal subunit (sensu Eukarya), NR | 2 genes |
| cytoskeleton, ISS | 2 genes |
| cell-cell adherens junction, NR | 2 genes |
| calcineurin complex, NAS | 2 genes |
| citrate metabolism, TAS | 2 genes |
| cAMP biosynthesis, TAS | 2 genes |
| chromatin assembly/disassembly, TAS | 2 genes |
| chromatin remodeling, IDA | 2 genes |
| chromatin silencing, TAS | 2 genes |
| cysteinyl-tRNA aminoacylation, IEA | 2 genes |
| cysteine metabolism, TAS | 2 genes |
| creatine biosynthesis, TAS | 2 genes |
| ceramide metabolism, IEA | 2 genes |
| ceramide metabolism, ISS | 2 genes |
| ceramide metabolism, NAS | 2 genes |
| calcium ion transport, ISS | 2 genes |
| chloride transport, NAS | 2 genes |
| chloride transport, TAS | 2 genes |
| cell ion homeostasis, TAS | 2 genes |
| calcium ion homeostasis, ISS | 2 genes |
| chemotaxis, IDA | 2 genes |
| cytoskeletal anchoring, NAS | 2 genes |
| cell cycle arrest, IMP | 2 genes |
| centrosome cycle, TAS | 2 genes |
| cell-matrix adhesion, NR | 2 genes |
| cell-cell signaling, ISS | 2 genes |
| chemokine activity, NR | 2 genes |
| cholesterol metabolism, ISS | 2 genes |
| cysteine-type peptidase activity, NAS | 2 genes |
| cellular_component unknown, NAS | 2 genes |
| caspase activation via cytochrome c, TAS | 2 genes |
| caspase activator activity, TAS | 2 genes |
| cyanate catabolism, TAS | 2 genes |
| cell surface, IEA | 2 genes |
| cell surface, ISS | 2 genes |
| cell surface, NAS | 2 genes |
| cell-cell recognition, TAS | 2 genes |
| cardioblast differentiation, ISS | 2 genes |
| corticotrophin-releasing factor receptor activity, TAS | 2 genes |
| calcium ion transporter activity, TAS | 2 genes |
| choline transporter activity, TAS | 2 genes |
| calcium-activated potassium channel activity, IDA | 2 genes |
| calcium-activated potassium channel activity, IEA | 2 genes |
| calcium-activated potassium channel activity, TAS | 2 genes |
| cyclin-dependent protein kinase 5 activator complex, IEA | 2 genes |
| cyclin-dependent protein kinase 5 activator activity, IEA | 2 genes |
| chromatin remodeling complex, NAS | 2 genes |
| cytokine and chemokine mediated signaling pathway, IEA | 2 genes |
| cytokine and chemokine mediated signaling pathway, TAS | 2 genes |
| centromeric DNA binding, TAS | 2 genes |
| cell homeostasis, NAS | 2 genes |
| cation-transporting ATPase activity, NAS | 2 genes |
| clathrin coat of trans-Golgi network vesicle, ISS | 2 genes |
| cell differentiation, IDA | 2 genes |
| clathrin binding, ISS | 2 genes |
| cholesterol absorption, NAS | 2 genes |
| cholesterol transport, IEA | 2 genes |
| collagen catabolism, NAS | 2 genes |
| caspase activity, NAS | 2 genes |
| cAMP metabolism, TAS | 2 genes |
| ceramide cholinephosphotransferase activity, IDA | 2 genes |
| cholestenol delta-isomerase activity, IEA | 2 genes |
| chromatin-mediated maintenance of transcription, NAS | 2 genes |
| cobalt ion binding, IEA | 2 genes |
| Cytochrom_C, Cytochrome c. The cytochrome 556 and cytochrome c' families are not included | 1 genes |
| Cellulase, Cellulase (glycosyl hydrolase family 5) | 1 genes |
| Catalase, Catalase | 1 genes |
| Complex1_30kDa, Respiratory-chain NADH dehydrogenase, 30 Kd subunit | 1 genes |
| Complex1_49kDa, Respiratory-chain NADH dehydrogenase, 49 Kd subunit | 1 genes |
| COX3, Cytochrome c oxidase subunit III | 1 genes |
| CLP_protease, Clp protease. The Clp protease has an active site catalytic triad. In E. coli Clp protease, ser-111, his-136 and asp-185 form the catalytic triad. One member has lost all of these active site residues and is therefore inactive. S | 1 genes |
| Cathelicidins, Cathelicidin. A novel protein family, showing a conserved proregion and a variable carboxyl-terminal antimicrobial domain. This region shows similarity to cystatins | 1 genes |
| Calpain_inhib, Calpain inhibitor. This region is found multiple times in calpain inhibitor proteins | 1 genes |
| Cys_rich_FGFR, Cysteine rich repeat. This cysteine rich repeat contains four cysteines. It is found in multiple copies in a protein that binds to fibroblast growth factors. The repeat is also found in MG160 and E-selectin ligand (ESL-1) | 1 genes |
| CIMR, Cation-independent mannose-6-phosphate receptor repeat. The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat | 1 genes |
| Casein_kappa, Kappa casein. Kappa-casein is a mammalian milk protein involved in a number of important physiological processes. In the gut, the ingested protein is split into an insoluble peptide (para kappa-casein) and a soluble hydrophilic g | 1 genes |
| CNTF, Ciliary neurotrophic factor | 1 genes |
| Colipase, N-terminal domain. SCOP reports duplication of common fold with Colipase C-terminal domain | 1 genes |
| CK_II_beta, Casein kinase II regulatory subunit | 1 genes |
| COX5B, Cytochrome c oxidase subunit Vb | 1 genes |
| Coprogen_oxidas, Coproporphyrinogen III oxidase | 1 genes |
| Carb_kinase, Carbohydrate kinase. This family is related to pfam02110 and pfam00294 implying that it also is a carbohydrate kinase. (personal obs Yeats C) | 1 genes |
| Complex1_24kDa, Respiratory-chain NADH dehydrogenase 24 Kd subunit | 1 genes |
| Cyto_heme_lyase, Cytochrome c/c1 heme lyase | 1 genes |
| Complex1_51K, Respiratory-chain NADH dehydrogenase 51 Kd subunit | 1 genes |
| Corona_S2, Coronavirus S2 glycoprotein. The coronavirus spike glycoprotein forms the characteristic 'corona' after which the group is named. The Spike glycoprotein is translated as a large polypeptide that is subsequently cleaved to S1 pfam016 | 1 genes |
| Chorion_1, Chorion protein. This family consists of the chorion superfamily proteins classes A, B, CA, CB and high-cysteine HCB from silk, gypsy and polyphemus moths. The chorion proteins make up the moths egg shell a complex extracellular str | 1 genes |
| Cob_adeno_trans, Cobalamin adenosyltransferase. Cobalamin adenosyltransferase This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase ac | 1 genes |
| CYTH, CYTH domain | 1 genes |
| CBFB_NFYA, CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B | 1 genes |
| Cytochrom_C1, Cytochrome C1 family | 1 genes |
| COX5A, Cytochrome c oxidase subunit Va. Cytochrome c oxidase, a 13 sub-unit complex, EC:1.9.3.1 is the terminal oxidase in the mitochondrial electron transport chain. This family is composed of cytochrome c oxidase subunit Va | 1 genes |
| CBF_beta, Core binding factor beta subunit. Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subuni | 1 genes |
| Cyto_ox_2, Cytochrome oxidase subunit II. This Family consists of cytochrome bd type terminal oxidases that catalyses Quinol dependent, Na+ independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohea | 1 genes |
| CTP_transf_3, Cytidylyltransferase. This family consists of two main Cytidylyltransferase activities: 1) 3-deoxy-manno-octulosonate cytidylyltransferase, EC:2.7.7.38 catalysing the reaction:- CTP + 3-deoxy-D-manno-octulosonate <=> diphosphate | 1 genes |
| CLN3, CLN3 protein. This is a family of proteins from the CLN3 gene. A missense mutation of glutamic acid (E) to lysine (K) at position 295 in the human protein has been implicated in Juvenile neuronal ceroid lipofuscinosis (Batten disease) | 1 genes |
| CO_dh, CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit. This family consists of Carbon monoxide dehydrogenase I/II beta subunit EC:1.2.99.2 and acetyl-CoA synthase epsilon subunit. Carbon monoxide beta subunit catalyses the r | 1 genes |
| COX15-CtaA, Cytochrome oxidase assembly protein. This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast | 1 genes |
| Colipase_C, Colipase, C-terminal domain. SCOP reports duplication of common fold with Colipase N-terminal domain | 1 genes |
| CDC48_2, Cell division protein 48 (CDC48), domain 2. This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domain | 1 genes |
| COX7C, Cytochrome c oxidase subunit VIIc. Cytochrome c oxidase, a 13 sub-unit complex, EC:1.9.3.1 is the terminal oxidase in the mitochondrial electron transport chain. This family is composed of cytochrome c oxidase subunit VIIc. The yeast me | 1 genes |
| COX6C, Cytochrome c oxidase subunit VIc. Cytochrome c oxidase, a 13 sub-unit complex, EC:1.9.3.1 is the terminal oxidase in the mitochondrial electron transport chain. This family is composed of cytochrome c oxidase subunit VIc | 1 genes |
| CutA1, CutA1 divalent ion tolerance protein. Several gene loci with a possible involvement in cellular tolerance to copper have been identified. One such locus in eubacteria and archaebacteria, cutA, is thought to be involved in cellular toler | 1 genes |
| COQ7, Ubiquinone biosynthesis protein COQ7. Members of this family contain two repeats of about 90 amino acids, that contains two conserved motifs. One of these DXEXXH may be part of an enzyme active site | 1 genes |
| CAS_CSE1, CAS/CSE protein, C-terminus. Mammalian cellular apoptosis susceptibility (CAS) proteins are homologous to the yeast chromosome-segregation protein, CSE1. This family aligns the C-terminal halves (approximately). CAS is involved in bo | 1 genes |
| Connexin43, Gap junction alpha-1 protein (Cx43) | 1 genes |
| Connexin50, Gap junction alpha-8 protein (Cx50) | 1 genes |
| Competence, Competence protein. Members of this family are integral membrane proteins with 6 predicted transmembrane helices. Some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. | 1 genes |
| CLAG, Cytoadherence-linked asexual protein. Clag (cytoadherence linked asexual gene) is a malaria surface protein which has been shown to be involved in the binding of Plasmodium falciparum infected erythrocytes to host endothelial cells, a pr | 1 genes |
| Cgr1, Cgr1 family. Members of this family are coiled-coil proteins that are involved in pre-rRNA processing | 1 genes |
| CutC, CutC family. Copper transport in Escherichia coli is mediated by the products of at least six genes, cutA, cutB, cutC, cutD, cutE, and cutF. A mutation in one or more of these genes results in an increased copper sensitivity. Members of | 1 genes |
| CtaG_Cox11, Cytochrome c oxidase assembly protein CtaG / Cox11. Cytochrome c oxidase assembly protein is essential for the assembly of functional cytochrome oxidase protein. In eukaryotes it is an integral protein of the mitochondrial inner me | 1 genes |
| Ceramidase_alk, Neutral/alkaline non-lysosomal ceramidase. This family represents a group of neutral/alkaline ceramidases found in both bacteria and eukaryotes | 1 genes |
| ChaC, ChaC-like protein. The ChaC protein is thought to be associated with the putative ChaA Ca2+/H+ cation transport protein in Escherichia coli. Its function is not known. This family also includes homologues regions from several other bacte | 1 genes |
| Coq4, Coenzyme Q (ubiquinone) biosynthesis protein Coq4. Coq4p was shown to peripherally associate with the matrix face of the mitochondrial inner membrane. The putative mitochondrial- targeting sequence present at the amino-terminus of the po | 1 genes |
| COX17, Cytochrome C oxidase copper chaperone (COX17). Cox17 is essential for the assembly of functional cytochrome c oxidase (CCO) and for delivery of copper ions to the mitochondrion for insertion into the enzyme in yeast | 1 genes |
| CDC73, RNA pol II accessory factor, Cdc73 family | 1 genes |
| CSF-1, Macrophage colony stimulating factor-1 (CSF-1). Colony stimulating factor 1 (CSF-1) is a homodimeric polypeptide growth factor whose primary function is to regulate the survival, proliferation, differentiation, and function of cells of | 1 genes |
| Chorion_3, Chorion family 3. This family consists of several Drosophila chorion proteins S36 and S38. The chorion genes of Drosophila are amplified in response to developmental signals in the follicle cells of the ovary | 1 genes |
| CRF-BP, Corticotropin-releasing factor binding protein (CRF-BP). This family consists of several eukaryotic corticotropin-releasing factor binding proteins (CRF-BP or CRH-BP). Corticotropin-releasing hormone (CRH) plays multiple roles in verte | 1 genes |
| Chlam_CT223, Chlamydia inclusion membrane protein CT223. This family consists of several Chlamydia CT223 inclusion membrane proteins | 1 genes |
| CDKN3, Cyclin-dependent kinase inhibitor 3 (CDKN3). This family consists of cyclin-dependent kinase inhibitor 3 or kinase associated phosphatase proteins from several mammalian species. The cyclin-dependent kinase (Cdk)-associated protein phos | 1 genes |
| Coiled, Coiled coil. This region is found in a group of Dictyostelium discoideum proteins. It is likely to form a coiled-coil. Some of the proteins are regulated by cyclic AMP and are expressed late in development | 1 genes |
| CENP-H, Centromere protein H (CENP-H). This family consists of several eukaryotic centromere protein H (CENP-H) sequences. Macromolecular centromere-kinetochore complex plays a critical role in sister chromatid separation, but its complete pro | 1 genes |
| CDO_I, Cysteine dioxygenase type I. Cysteine dioxygenase type I (EC:1.13.11.20) converts cysteine to cysteinesulphinic acid and is the rate-limiting step in sulphate production | 1 genes |
| COBRA1, Cofactor of BRCA1 (COBRA1). This family consists of several cofactor of BRCA1 (COBRA1) like proteins. It is thought that COBRA1 along with BRCA1 is involved in chromatin unfolding. COBRA1 is recruited to the chromosome site by the firs | 1 genes |
| CART, Cocaine and amphetamine regulated transcript protein (CART). This family consists of several cocaine and amphetamine regulated transcript type I protein (CART) sequences. Cocaine and amphetamine regulated transcript (CART) peptide has be | 1 genes |
| Churchill, Churchill protein. This family consists of several eukaryotic Churchill proteins. This protein contains a novel zinc binding region that mediates FGF signaling during neural development (unpublished obs Sheng G and Stern C) | 1 genes |
| C5-epim_C, D-glucuronyl C5-epimerase C-terminus. This family represents the C-terminus of D-glucuronyl C5-epimerase (EC:5.1.3.-). Glucuronyl C5-epimerases catalyse the conversion of D-glucuronic acid (GlcUA) to L-iduronic acid (IdceA) units du | 1 genes |
| CI-B14_5a, NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a). This family contains the eukaryotic NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) (EC:1.6.5.3). This is approximately 100 residues long, and forms | 1 genes |
| CHRD, CHRD domain. CHRD is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologues. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited si | 1 genes |
| centromere and kinetochore complex maturation, IDA | 1 genes |
| centromere and kinetochore complex maturation, TAS | 1 genes |
| cell cycle checkpoint, IDA | 1 genes |
| cell cycle checkpoint, ISS | 1 genes |
| cell cycle checkpoint, NAS | 1 genes |
| cytoplasmic exosome (RNase complex), IDA | 1 genes |
| C-8 sterol isomerase activity, IEA | 1 genes |
| C-5 sterol desaturase activity, TAS | 1 genes |
| C-4 methyl sterol oxidase activity, TAS | 1 genes |
| cell fraction, NAS | 1 genes |
| chromosome, telomeric region, IDA | 1 genes |
| chromosome, telomeric region, TAS | 1 genes |
| chromatin, IDA | 1 genes |
| cytoplasmic chromatin, IDA | 1 genes |
| condensed nuclear chromosome, IDA | 1 genes |
| condensin complex, TAS | 1 genes |
| condensin core heterodimer, NAS | 1 genes |
| cellular morphogenesis, IMP | 1 genes |
| cellular morphogenesis, ISS | 1 genes |
| cellular morphogenesis, NAS | 1 genes |
| cytokinesis, ISS | 1 genes |
| cytokinesis, NR | 1 genes |
| cornified envelope, IEA | 1 genes |
| ciliary/flagellar motility, NAS | 1 genes |
| ceramide kinase activity, IDA | 1 genes |
| co-chaperone activity, IEA | 1 genes |
| co-chaperone activity, ISS | 1 genes |
| co-chaperone activity, NR | 1 genes |
| coagulation factor VIIa activity, TAS | 1 genes |
| coagulation factor IXa activity, NAS | 1 genes |
| coagulation factor IXa activity, TAS | 1 genes |
| coagulation factor Xa activity, TAS | 1 genes |
| coagulation factor XIIa activity, TAS | 1 genes |
| classical-complement-pathway C3/C5 convertase activity, IEA | 1 genes |
| complement component C1r activity, TAS | 1 genes |
| complement component C1s activity, TAS | 1 genes |
| complement factor D activity, IEA | 1 genes |
| complement factor D activity, TAS | 1 genes |
| complement factor I activity, TAS | 1 genes |
| catalytic activity, TAS | 1 genes |
| CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity, IEA | 1 genes |
| CTP synthase activity, IEA | 1 genes |
| carbamoyl-phosphate synthase (ammonia) activity, TAS | 1 genes |
| carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity, TAS | 1 genes |
| carbonyl reductase (NADPH) activity, IEA | 1 genes |
| carboxylesterase activity, TAS | 1 genes |
| carnitine O-acetyltransferase activity, IEA | 1 genes |
| carnitine O-palmitoyltransferase activity, IEA | 1 genes |
| carnitine O-palmitoyltransferase activity, NAS | 1 genes |
| catalase activity, IEA | 1 genes |
| catalase activity, TAS | 1 genes |
| cerebroside-sulfatase activity, IEA | 1 genes |
| choline O-acetyltransferase activity, IEA | 1 genes |
| choline kinase activity, NAS | 1 genes |
| choline kinase activity, TAS | 1 genes |
| cholinesterase activity, IEA | 1 genes |
| cholinesterase activity, NAS | 1 genes |
| citrate (Si)-synthase activity, IEA | 1 genes |
| citrate (Si)-synthase activity, TAS | 1 genes |
| coproporphyrinogen oxidase activity, IEA | 1 genes |
| coproporphyrinogen oxidase activity, TAS | 1 genes |
| cGMP-specific phosphodiesterase activity, IEA | 1 genes |
| cGMP-stimulated cyclic-nucleotide phosphodiesterase activity, TAS | 1 genes |
| cystathionine beta-synthase activity, TAS | 1 genes |
| cystathionine gamma-lyase activity, IEA | 1 genes |
| cytidine deaminase activity, NAS | 1 genes |
| cytidylate kinase activity, IEA | 1 genes |
| cytochrome-b5 reductase activity, IDA | 1 genes |
| cytochrome-c oxidase activity, IDA | 1 genes |
| cytochrome-c oxidase activity, NAS | 1 genes |
| carboxypeptidase activity, NAS | 1 genes |
| carboxypeptidase A activity, ISS | 1 genes |
| carboxypeptidase E activity, IEA | 1 genes |
| carboxypeptidase C activity, IEA | 1 genes |
| carboxypeptidase D activity, TAS | 1 genes |
| cathepsin D activity, TAS | 1 genes |
| cathepsin E activity, IDA | 1 genes |
| cysteine-type endopeptidase activity, IDA | 1 genes |
| cysteine-type endopeptidase activity, NR | 1 genes |
| calpain activity, NAS | 1 genes |
| cathepsin B activity, IEA | 1 genes |
| cathepsin B activity, TAS | 1 genes |
| cathepsin H activity, TAS | 1 genes |
| cathepsin K activity, TAS | 1 genes |
| cathepsin S activity, TAS | 1 genes |
| cathepsin G activity, TAS | 1 genes |
| chymotrypsin activity, NAS | 1 genes |
| calcidiol 1-monooxygenase activity, NR | 1 genes |
| chitinase activity, IDA | 1 genes |
| chitinase activity, TAS | 1 genes |
| CAAX-protein geranylgeranyltransferase activity, TAS | 1 genes |
| calmodulin-dependent protein kinase I activity, TAS | 1 genes |
| cyclin-dependent protein kinase activity, IEA | 1 genes |
| cyclin-dependent protein kinase activity, NR | 1 genes |
| copper, zinc superoxide dismutase activity, TAS | 1 genes |
| cyclin-dependent protein kinase inhibitor activity, IEA | 1 genes |
| cyclin-dependent protein kinase inhibitor activity, NAS | 1 genes |
| cAMP-dependent protein kinase inhibitor activity, IEA | 1 genes |
| cAMP-dependent protein kinase inhibitor activity, TAS | 1 genes |
| cysteine protease inhibitor activity, NAS | 1 genes |
| complement receptor activity, NAS | 1 genes |
| complement component C3a receptor activity, TAS | 1 genes |
| complement component C3b receptor activity, NR | 1 genes |
| ciliary neurotrophic factor receptor activity, TAS | 1 genes |
| C3a anaphylatoxin receptor activity, TAS | 1 genes |
| C5a anaphylatoxin receptor activity, IEA | 1 genes |
| C5a anaphylatoxin receptor activity, TAS | 1 genes |
| calcitonin receptor activity, IEA | 1 genes |
| calcitonin receptor activity, NAS | 1 genes |
| calcitonin receptor activity, TAS | 1 genes |
| chemokine receptor activity, NR | 1 genes |
| cholecystokinin receptor activity, TAS | 1 genes |
| ciliary neurotrophic factor receptor binding, TAS | 1 genes |
| CD40 receptor binding, IPI | 1 genes |
| CD27 receptor binding, IEA | 1 genes |
| calcium activated cation channel activity, NAS | 1 genes |
| chloride channel activity, IEA | 1 genes |
| channel-conductance-controlling ATPase activity, NAS | 1 genes |
| cation channel activity, NAS | 1 genes |
| creatine:sodium symporter activity, TAS | 1 genes |
| carrier activity, IDA | 1 genes |
| calcium-transporting ATPase activity, NR | 1 genes |
| CMP-sialic acid transporter activity, TAS | 1 genes |
| copper ion binding, IDA | 1 genes |
| copper ion binding, NR | 1 genes |
| calcium ion binding, IC | 1 genes |
| calcium ion storage activity, NR | 1 genes |
| calmodulin binding, NR | 1 genes |
| calmodulin inhibitor activity, NAS | 1 genes |
| collagen binding, IPI | 1 genes |
| cytoskeletal regulatory protein binding, TAS | 1 genes |
| collagen, NAS | 1 genes |
| collagen type XV, NR | 1 genes |
| collagen type II, NR | 1 genes |
| collagen type III, TAS | 1 genes |
| collagen type IV, NAS | 1 genes |
| collagen type IV, NR | 1 genes |
| collagen type VI, NAS | 1 genes |
| collagen type VI, TAS | 1 genes |
| collagen type VII, TAS | 1 genes |
| collagen type VIII, TAS | 1 genes |
| collagen type XI, NAS | 1 genes |
| collagen type XI, TAS | 1 genes |
| collagen type XII, NAS | 1 genes |
| collagen type XII, TAS | 1 genes |
| collagen type XIV, NAS | 1 genes |
| collagen type XVI, TAS | 1 genes |
| collagen type XIII, TAS | 1 genes |
| complement component C2 complex, TAS | 1 genes |
| cell wall, NR | 1 genes |
| chromosome, TAS | 1 genes |
| centric heterochromatin, IDA | 1 genes |
| cytoplasm, IMP | 1 genes |
| centrosome, IEP | 1 genes |
| centrosome, NAS | 1 genes |
| centriole, IDA | 1 genes |
| contractile ring, ISS | 1 genes |
| cytosolic ribosome (sensu Eukarya), TAS | 1 genes |
| cytosolic large ribosomal subunit (sensu Eukarya), ISS | 1 genes |
| cytosolic large ribosomal subunit (sensu Eukarya), NAS | 1 genes |
| cytoskeleton, IDA | 1 genes |
| cytoplasmic microtubule, NAS | 1 genes |
| caveola, NR | 1 genes |
| caveola, TAS | 1 genes |
| coated pit, IDA | 1 genes |
| coated pit, NAS | 1 genes |
| coated pit, NR | 1 genes |
| coated pit, TAS | 1 genes |
| connexon complex, IDA | 1 genes |
| connexon complex, NR | 1 genes |
| cilium, NR | 1 genes |
| cilium, TAS | 1 genes |
| cell cortex, ISS | 1 genes |
| CAAX-protein geranylgeranyltransferase complex, TAS | 1 genes |
| calcineurin complex, IDA | 1 genes |
| calcineurin complex, NR | 1 genes |
| carbohydrate metabolism, NAS | 1 genes |
| chitin catabolism, IEA | 1 genes |
| chitin catabolism, NAS | 1 genes |
| cell wall chitin metabolism, TAS | 1 genes |
| cAMP biosynthesis, IEP | 1 genes |
| chromatin assembly/disassembly, IMP | 1 genes |
| chromatin remodeling, IEA | 1 genes |
| chromatin silencing, IEP | 1 genes |
| C-terminal protein amino acid methylation, TAS | 1 genes |
| cysteine biosynthesis from serine, IEA | 1 genes |
| CDP-choline pathway, ISS | 1 genes |
| ceramide metabolism, IDA | 1 genes |
| cholesterol biosynthesis, NAS | 1 genes |
| cholesterol biosynthesis, NR | 1 genes |
| cholesterol catabolism, IDA | 1 genes |
| cholesterol catabolism, NAS | 1 genes |
| cholesterol catabolism, TAS | 1 genes |
| cation transport, ISS | 1 genes |
| chloride transport, IDA | 1 genes |
| chloride transport, ISS | 1 genes |
| copper ion transport, IEA | 1 genes |
| cell ion homeostasis, IC | 1 genes |
| cell ion homeostasis, ISS | 1 genes |
| cell ion homeostasis, NAS | 1 genes |
| calcium ion homeostasis, NR | 1 genes |
| copper ion homeostasis, NR | 1 genes |
| caspase activation, IDA | 1 genes |
| caspase activation, ISS | 1 genes |
| cell motility, IDA | 1 genes |
| cell motility, IGI | 1 genes |
| cell motility, ISS | 1 genes |
| chemotaxis, NAS | 1 genes |
| complement activation, IEA | 1 genes |
| complement activation, TAS | 1 genes |
| complement activation, alternative pathway, NAS | 1 genes |
| complement activation, classical pathway, NAS | 1 genes |
| complement activation, classical pathway, TAS | 1 genes |
| cellular defense response, NAS | 1 genes |
| chromosome organization and biogenesis (sensu Eukarya), ISS | 1 genes |
| cytoskeletal anchoring, ISS | 1 genes |
| chaperonin-mediated tubulin folding, IEA | 1 genes |
| chaperonin-mediated tubulin folding, TAS | 1 genes |
| cell-substrate junction assembly, TAS | 1 genes |
| cell cycle, IDA | 1 genes |
| cell cycle, ISS | 1 genes |
| cell cycle, NR | 1 genes |
| cell cycle arrest, NAS | 1 genes |
| chromosome segregation, NAS | 1 genes |
| centrosome separation, TAS | 1 genes |
| cell communication, NR | 1 genes |
| cell-matrix adhesion, IDA | 1 genes |
| cell-matrix adhesion, IPI | 1 genes |
| cell-matrix adhesion, ISS | 1 genes |
| calcium-independent cell-matrix adhesion, TAS | 1 genes |
| cell surface receptor linked signal transduction, IC | 1 genes |
| cell surface receptor linked signal transduction, IMP | 1 genes |
| cytosolic calcium ion concentration elevation, NAS | 1 genes |
| cytoplasmic sequestering of NF-kappaB, TAS | 1 genes |
| cell-cell signaling, IDA | 1 genes |
| compartment specification, IDA | 1 genes |
| central nervous system development, IDA | 1 genes |
| central nervous system development, IEP | 1 genes |
| central nervous system development, NR | 1 genes |
| cell aging, IMP | 1 genes |
| cell aging, TAS | 1 genes |
| copulation, IEA | 1 genes |
| circadian rhythm, NAS | 1 genes |
| circadian rhythm, NR | 1 genes |
| chemokine activity, IDA | 1 genes |
| chemokine activity, NAS | 1 genes |
| circulation, NAS | 1 genes |
| cell recognition, IDA | 1 genes |
| cell recognition, ISS | 1 genes |
| chitin binding, TAS | 1 genes |
| cytoskeletal protein binding, ISS | 1 genes |
| cytoskeletal protein binding, NAS | 1 genes |
| cytoskeletal adaptor activity, ISS | 1 genes |
| ceramide glucosyltransferase activity, TAS | 1 genes |
| cholesterol 7-alpha-monooxygenase activity, IEA | 1 genes |
| cAMP response element binding protein binding, NAS | 1 genes |
| cell growth and/or maintenance, IDA | 1 genes |
| cell growth and/or maintenance, ISS | 1 genes |
| calcium, potassium:sodium antiporter activity, NAS | 1 genes |
| cohesin complex, NAS | 1 genes |
| cohesin core heterodimer, TAS | 1 genes |
| calcium- and calmodulin-responsive adenylate cyclase activity, NAS | 1 genes |
| calcium- and calmodulin-responsive adenylate cyclase activity, TAS | 1 genes |
| cation transporter activity, TAS | 1 genes |
| cholesterol monooxygenase (side-chain-cleaving) activity, IEA | 1 genes |
| coumarin 7-hydroxylase activity, TAS | 1 genes |
| CTD phosphatase activity, ISS | 1 genes |
| carnitine O-octanoyltransferase activity, TAS | 1 genes |
| chondroitin 6-sulfotransferase activity, IEA | 1 genes |
| chondroitin 6-sulfotransferase activity, TAS | 1 genes |
| cAMP-dependent protein kinase regulator activity, NAS | 1 genes |
| cAMP-dependent protein kinase regulator activity, NR | 1 genes |
| chromatin accessibility complex, NAS | 1 genes |
| caspase activation via cytochrome c, IDA | 1 genes |
| caspase activation via cytochrome c, NAS | 1 genes |
| choline dehydrogenase activity, IEA | 1 genes |
| citrate (pro-3S)-lyase activity, IEA | 1 genes |
| crossover junction endodeoxyribonuclease activity, IEA | 1 genes |
| catabolism, IEA | 1 genes |
| cyclic nucleotide metabolism, ISS | 1 genes |
| cyclic nucleotide metabolism, TAS | 1 genes |
| cyclic nucleotide catabolism, IEA | 1 genes |
| cellular response to starvation, ISS | 1 genes |
| citrate lyase complex, IEA | 1 genes |
| citrate lyase complex, TAS | 1 genes |
| cold acclimation, IEA | 1 genes |
| carbohydrate mediated signaling, TAS | 1 genes |
| cellular osmoregulation, ISS | 1 genes |
| coreceptor activity, NR | 1 genes |
| Cajal body, NAS | 1 genes |
| Cajal body, TAS | 1 genes |
| chloride transporter activity, NR | 1 genes |
| chloride transporter activity, TAS | 1 genes |
| citrate transporter activity, TAS | 1 genes |
| carnitine transporter activity, IDA | 1 genes |
| carnitine transporter activity, ISS | 1 genes |
| carnitine transporter activity, TAS | 1 genes |
| connexon channel activity, IDA | 1 genes |
| connexon channel activity, NR | 1 genes |
| cystine:glutamate antiporter activity, TAS | 1 genes |
| cation diffusion facilitator activity, TAS | 1 genes |
| cholesterol binding, IDA | 1 genes |
| cholesterol binding, NAS | 1 genes |
| cholesterol binding, TAS | 1 genes |
| canalicular bile acid transport, TAS | 1 genes |
| CMP-sialic acid transport, TAS | 1 genes |
| choline transport, TAS | 1 genes |
| carnitine transport, IDA | 1 genes |
| carnitine transport, ISS | 1 genes |
| carnitine transport, TAS | 1 genes |
| coenzyme A metabolism, TAS | 1 genes |
| cytoplasmic vesicle, IDA | 1 genes |
| cytoplasmic vesicle, ISS | 1 genes |
| cytoplasmic vesicle, NAS | 1 genes |
| cell growth, TAS | 1 genes |
| carbohydrate biosynthesis, ISS | 1 genes |
| changes in polarization state of photoreceptor cell membrane, TAS | 1 genes |
| cellular defense response (sensu Vertebrata), IMP | 1 genes |
| cellular defense response (sensu Vertebrata), ISS | 1 genes |
| cellular defense response (sensu Vertebrata), NAS | 1 genes |
| cellular defense response (sensu Vertebrata), TAS | 1 genes |
| carotene metabolism, IDA | 1 genes |
| catechol O-methyltransferase activity, IEA | 1 genes |
| calcium-independent cell-cell adhesion, IDA | 1 genes |
| calcium-dependent cell-cell adhesion, ISS | 1 genes |
| CoA-ligase activity, IEA | 1 genes |
| cell migration, ISS | 1 genes |
| cytoplasmic transport, IDA | 1 genes |
| C-C chemokine receptor activity, NAS | 1 genes |
| copper chaperone activity, IEA | 1 genes |
| chromatin modification, IDA | 1 genes |
| carboxylic ester hydrolase activity, IEA | 1 genes |
| carboxylic ester hydrolase activity, ISS | 1 genes |
| carbon-sulfur lyase activity, IEA | 1 genes |
| ceramidase activity, IEA | 1 genes |
| calcium ion-dependent exocytosis, TAS | 1 genes |
| cysteine dioxygenase activity, IEA | 1 genes |
| cytokine and chemokine mediated signaling pathway, ISS | 1 genes |
| cytokine and chemokine mediated signaling pathway, NAS | 1 genes |
| cysteine biosynthesis via cystathione, IEA | 1 genes |
| cysteine biosynthesis, IEA | 1 genes |
| cyclooxygenase pathway, NAS | 1 genes |
| calcium-mediated signaling, IDA | 1 genes |
| cell homeostasis, ISS | 1 genes |
| calcium channel inhibitor activity, NAS | 1 genes |
| cAMP-mediated signaling, NAS | 1 genes |
| cGMP-mediated signaling, NAS | 1 genes |
| cytokine binding, IEA | 1 genes |
| cytokine binding, NAS | 1 genes |
| CCR4-NOT complex, NAS | 1 genes |
| cell junction, NAS | 1 genes |
| COPI vesicle coat, NAS | 1 genes |
| clathrin coat of trans-Golgi network vesicle, NAS | 1 genes |
| coated vesicle, ISS | 1 genes |
| clathrin-coated vesicle, NAS | 1 genes |
| COPI-coated vesicle, TAS | 1 genes |
| calpain inhibitor activity, IEA | 1 genes |
| chondroitin sulfate biosynthesis, IDA | 1 genes |
| chondroitin sulfate biosynthesis, NAS | 1 genes |
| carbohydrate binding, IEA | 1 genes |
| carbohydrate binding, NAS | 1 genes |
| chromosome condensation, IDA | 1 genes |
| chymase activity, IEA | 1 genes |
| clathrin binding, IDA | 1 genes |
| cholesterol transport, NAS | 1 genes |
| chymotrypsin inhibitor activity, NAS | 1 genes |
| cytoplasmic vesicle membrane, IDA | 1 genes |
| cytoplasmic vesicle membrane, ISS | 1 genes |
| caspase activity, NR | 1 genes |
| cortical actin cytoskeleton, IDA | 1 genes |
| cortical actin cytoskeleton organization and biogenesis, IDA | 1 genes |
| chemokine biosynthesis, TAS | 1 genes |
| cell-mediated immune response, IDA | 1 genes |
| cytokine biosynthesis, TAS | 1 genes |
| chromaffin granule, NAS | 1 genes |
| chylomicron, IEA | 1 genes |
| cholesterol homeostasis, TAS | 1 genes |
| cystic fibrosis transmembrane conductance regulator binding, ISS | 1 genes |
| calcium-dependent phospholipase A2 activation, IDA | 1 genes |
| cell body, NAS | 1 genes |
| caspase inhibitor activity, IMP | 1 genes |
| cellular extravasation, NAS | 1 genes |
| clustering of voltage gated sodium channels, IDA | 1 genes |
| clustering of voltage gated potassium channels, IDA | 1 genes |
| connective tissue growth factor biosynthesis, TAS | 1 genes |
| cadherin binding, IDA | 1 genes |
| carnitine biosynthesis, IEA | 1 genes |
| cellular respiration, ISS | 1 genes |
| cellular respiration, NAS | 1 genes |
| cytidine metabolism, IEA | 1 genes |
| calcium oxalate binding, NAS | 1 genes |
| cytosol to ER transport, ISS | 1 genes |
| cytosol to ER transport, NAS | 1 genes |
| calcium-dependent phospholipase A2 activity, IDA | 1 genes |
| calcium-dependent phospholipase A2 activity, NAS | 1 genes |
| calcium-independent phospholipase A2 activity, IDA | 1 genes |
| calcium-independent phospholipase A2 activity, ISS | 1 genes |
| chlordecone reductase activity, IEA | 1 genes |
| chondroitin 4-sulfotransferase activity, IDA | 1 genes |
| chondroitin 4-sulfotransferase activity, ISS | 1 genes |
| corticosterone 18-monooxygenase activity, IEA | 1 genes |
| cysteine-S-conjugate beta-lyase activity, IEA | 1 genes |
| chromatin-mediated maintenance of transcription, ISS | 1 genes |
| clathrin cage assembly, TAS | 1 genes |
| calcium-dependent protein binding, ISS | 1 genes |
| calcium-dependent protein binding, TAS | 1 genes |
| carboxypeptidase B activity, IEA | 1 genes |
| chondroitin sulfate proteoglycan biosynthesis, polysaccharide chain biosynthesis, IDA | 1 genes |
| chondroitin sulfate proteoglycan biosynthesis, polysaccharide chain biosynthesis, TAS | 1 genes |
| cytokine secretion, NAS | 1 genes |
| cocaine metabolism, TAS | 1 genes |
AS3D Human
